Molecular Basis of Ferroptosis-Immune Metabolism Crosstalk
Ferroptosis is a form of metabolic cell death jointly driven by disruption of iron homeostasis, accumulation of membrane lipid peroxidation, and failure of lipid antioxidant defense systems.
Topic
GPX4
Techniques for detecting, quantifying and localizing antigens and antibodies — ELISA, Western blotting, immunohistochemistry and flow cytometry. Below are the protocols, FAQs and technical articles in our knowledge base tagged with this topic.
2 resources · protocols, FAQs & articles
The Drug Target Potential of the GPX Family in Lipid Peroxidation Defense, Ferroptosis Regulation, and Organ Injury Protection
The GPX family constitutes an important enzymatic system in the regulation of cellular redox homeostasis and participates in peroxide clearance, termination of lipid peroxidation, maintenance of membrane homeostasis, and control of stress-induced injury. Different members exhibit clear ...
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Techniques often explored alongside immunological experiments.