In drug molecules, catalytic systems, separation/purification, and materials media, R&D often encounters a recurring challenge: the same molecule shows dramatically different behavior under different conditions, making results difficult to reproduce. Typical triggers fall into three main categories.
Imidazole is a five-membered aromatic heterocyclic compound with two nitrogen atoms. The hydrogen atom moves between the two nitrogen atoms, so there are two reciprocal isomers. Imidazole is not only present as histidine in living organisms, but is also a constituent of ribonucleic acid (RNA) ...
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