Artículos por tema "Solid-Phase Peptide Synthesis"

1. New Progress in the Solid-Phase Synthesis of Sterically Hindered Peptides: Background, Core Breakthroughs, and Implications for Automation Compatibility of the RMMR Strategy
   posted this at 22 mar 2026

   0
   Peptides have become an important class of molecules in modern medicinal chemistry and chemical biology. Compared with traditional small molecules, peptides often offer higher target selectivity and stronger molecular recognition capability, while still retaining good structural tunability. As a ...
2. A Complete Guide to Choosing Resins for SPPS (Solid-Phase Peptide Synthesis): Fmoc/Boc Routes, C-Terminal Acid/Amide, and a Key-Parameter Navigator
   posted this at 11 ene 2026

   1
   Solid-Phase Peptide Synthesis (SPPS) is a method in which a growing peptide chain is covalently “tethered” to insoluble resin beads, and the synthesis proceeds through repeated cycles of “deprotection → coupling one amino acid → washing.” Because the peptide remains attached to the ...