Techniques for detecting, quantifying and localizing antigens and antibodies — ELISA, Western blotting, immunohistochemistry and flow cytometry. Below are the protocols, FAQs and technical articles in our knowledge base tagged with this topic.
The extracellular matrix (ECM) in the tumor microenvironment not only supports tissue structure, but also continuously regulates immune cell infiltration, migration, activation, and effector functions through matrix deposition, crosslinking, degradation, and spatial reorganization. ECM ...
The TGF-β signaling pathway is an important molecular network that regulates cell fate, tissue homeostasis, and pathological remodeling. This pathway is centered on ligand activation, receptor complex assembly, and Smad-dependent transcriptional regulation, while also intersecting with non-Smad ...
Transforming growth factor-β (TGF-β) is a core member of a multifunctional cytokine family and exerts systemic influence in embryonic development, immune homeostasis, tissue repair, extracellular matrix (ECM) remodeling, and regulation of the tumor microenvironment. TGF-β initiates signaling ...
The TGF-β family (Transforming growth factor-beta family) includes members of TGF-β1, TGF-β2, TGF-β3, BMP (Bone morphogenetic protein), Activin, and Nodal, which play important roles in a variety of biological processes including cell proliferation, differentiation, apoptosis, extracellular ...
Techniques often explored alongside immunological experiments.
