When apoptosis occurs, chromosomal DNA double-strand breaks produce a large number of sticky 3'-OH ends, which can be labeled to the 3'-end of DNA by deoxyribonucleotide terminal transferase (TdT) and derivatives formed by fluorescein, peroxidase, alkaline phosphatase, or biotin to enable detection of apoptotic cells.
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Detection of apoptotic cells
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Da — when not otherwise indicated, molecular weight units are daltons. Mw — weight-average molecular weight. Mn — number-average molecular weight.
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Cite this article
Aladdin Scientific. "TUNEL staining of tissue sections" Aladdin Knowledge Base, updated 9 jun 2025. https://www.aladdinsci.com/us_es/faqs/tunel-staining-of-tissue-sections-en.html
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