Information
FDL169 FDL169 is a CFTR corrector that is designed to fix and restore the function of the defective CFTR protein.
Targets
CFTR
In vitro
FDL169 has been shown to increase Phe508del CFTR cell-surface abundance.
| ALogP | 3.87 |
|---|---|
| hba_count | 6 |
| Enlace rotable | 6 |
| Sonrisas canónicas | CCOC1=CC2=C(C=C1)C(=NN(C2=O)CC(=O)N(C)C3=CC4=C(C=C3)N=C(O4)C)C5=CC(=CC=C5)F |
|---|---|
| IUPAC Name | 2-[7-ethoxy-4-(3-fluorophenyl)-1-oxophthalazin-2-yl]-N-methyl-N-(2-methyl-1,3-benzoxazol-6-yl)acetamide |
| InChIKey | XRPSUWYWZUQALB-UHFFFAOYSA-N |
| INCHI | 1S/C27H23FN4O4/c1-4-35-20-9-10-21-22(14-20)27(34)32(30-26(21)17-6-5-7-18(28)12-17)15-25(33)31(3)19-8-11-23-24(13-19)36-16(2)29-23/h5-14H,4,15H2,1-3H3 |
| Isómeros SMILES | CCOC1=CC2=C(C=C1)C(=NN(C2=O)CC(=O)N(C)C3=CC4=C(C=C3)N=C(O4)C)C5=CC(=CC=C5)F |
| Peso molecular | 486.49 |
| Reaxy-Rn | 27186524 |
| Reaxys-RN_link_address | https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=27186524&ln= |
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →Full quality attributes and acceptance criteria for this grade.
View spec sheet →Taxonomy Tree
| Kingdom | Organic compounds |
|---|---|
| Superclass | Organoheterocyclic compounds |
| Clase | Diazines |
| Subclass | Pyridazines and derivatives |
| Intermediate Tree Nodes | Not available |
| Direct Parent | Phenylpyridazines |
| Alternative Parents | Phthalazinones Benzoxazoles Phenol ethers Pyridazinones Alkyl aryl ethers Fluorobenzenes Aryl fluorides Tertiary carboxylic acid amides Oxazoles Heteroaromatic compounds Lactams Oxacyclic compounds Azacyclic compounds Carbonyl compounds Hydrocarbon derivatives Organic oxides Organofluorides Organonitrogen compounds |
| Molecular Framework | Aromatic heteropolycyclic compounds |
| Substituents | Phenylpyridazine - Phthalazinone - Phthalazine - Benzoxazole - Phenol ether - Pyridazinone - Alkyl aryl ether - Halobenzene - Fluorobenzene - Aryl fluoride - Monocyclic benzene moiety - Benzenoid - Aryl halide - Azole - Heteroaromatic compound - Tertiary carboxylic acid amide - Oxazole - Carboxamide group - Lactam - Ether - Carboxylic acid derivative - Azacycle - Oxacycle - Organonitrogen compound - Organooxygen compound - Organic nitrogen compound - Carbonyl group - Hydrocarbon derivative - Organic oxide - Organic oxygen compound - Organohalogen compound - Organofluoride - Aromatic heteropolycyclic compound |
| Descripción | This compound belongs to the class of organic compounds known as phenylpyridazines. These are organic compounds containing a pyridazine ring substituted by a phenyl group. |
| External Descriptors | Not available |
Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Fecha | Articulo |
|---|---|---|---|
 E2423024 | Certificate of Analysis | Apr 02, 2026 | F421993 |
| DMSO (mg/ml) Solubilidad máxima | 33 |
|---|---|
| DMSO (mM) Solubilidad máxima | 67.8328434294641 |
| Agua (mg/ml) Solubilidad máxima | ＜1 |
| Peso molecular | 486.500 g/mol |
| XLogP3 | 4.600 |
| Hydrogen Bond Donor Count | 0 |
| Hydrogen Bond Acceptor Count | 7 |
| Rotatable Bond Count | 6 |
| Exact Mass | 486.17 Da |
| Monoisotopic Mass | 486.17 Da |
| Topological Polar Surface Area | 88.200 Ų |
| Heavy Atom Count | 36 |
| Formal Charge | 0 |
| Complexity | 856.000 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| The total count of all stereochemical bonds | 0 |
| Covalently-Bonded Unit Count | 1 |
