10 kDa for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Store at 2-8°C,Argon charged,Desiccated Ships Wet ice Check lot-specific COA for exact specifications.
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
FITC-DEAE-dextran is designed for special studies on membrane and transport properties in cells and tissues. Cationic (positively charged) diethylaminoethyl groups have been introduced into standard FITC-dextran. All batches are checked for molecular weight, degree of substitution, loss on drying and free FITC. Aladdin produce FITC-DEAE-dextrans from 4 kDa to 150 kDa. FITC-DEAE-dextrans are supplied as a yellow powder.Polysucrose are renamed from Ficoll™.
Structure
FITC-DEAE-dextrans are synthesized from well-characterised dextran fractions derived from Leuconostoc mesenteroides B512F. The degree of substitution for FITC lies between 0.001 – 0.008 and the limits for nitrogen content are 3-5% – corresponding to about one DEAE-substituent per three glucose units. The synthesis of DEAE-dextran introduces two types of DEAE-substituents into the dextran chain (see structure in datafile). The predominant substituent is the single tertiary group, but this reacts further particularly at higher degree of substitution to yield a “tandem” group containing a quaternary amine as well as the tertiary amine.
Spectral data
The excitation maximum for FITC-DEAE-dextran is 495 nm and the emission maximum is 520 nm. Maximum intensity is observed at pH 9.
Application
FITC-CM-dextran is mainly used for studying permeability and microcirculation. The diethylaminoethyl groups will impart an overall positive charge to the molecule, which may be valuable in gaining information on the permeability characteristics of cell membranes and tissues.
| Rangos de excitación y emisión | 495 nm and 520 nm |
|---|
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →Full quality attributes and acceptance criteria for this grade.
View spec sheet →Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Fecha | Articulo |
|---|---|---|---|
 B2313257 | Certificate of Analysis | Nov 11, 2022 | F292058 |
| B2313258 | Certificate of Analysis | Nov 11, 2022 | F292058 |
| B2313309 | Certificate of Analysis | Nov 11, 2022 | F292058 |
| B2313345 | Certificate of Analysis | Nov 11, 2022 | F292058 |
| B2521059 | Certificate of Analysis | Nov 11, 2022 | F292058 |
| I2509076 | Certificate of Analysis | Nov 11, 2022 | F292058 |
| Solubilidad | dissolves readily in water. |
|---|---|
| Sensibilidad | Moisture sensitive；light sensitive |
