Determine the necessary mass, volume, or concentration for preparing a solution.
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| Sonrisas canónicas | CN1CCN(CC1)C2=C(C=C3C(=C2F)N(C=C(C3=O)C(=O)O)CCF)F |
|---|---|
| IUPAC Name | 6,8-difluoro-1-(2-fluoroethyl)-7-(4-methylpiperazin-1-yl)-4-oxoquinoline-3-carboxylic acid |
| InChIKey | XBJBPGROQZJDOJ-UHFFFAOYSA-N |
| INCHI | 1S/C17H18F3N3O3/c1-21-4-6-22(7-5-21)15-12(19)8-10-14(13(15)20)23(3-2-18)9-11(16(10)24)17(25)26/h8-9H,2-7H2,1H3,(H,25,26) |
| Isómeros SMILES | CN1CCN(CC1)C2=C(C=C3C(=C2F)N(C=C(C3=O)C(=O)O)CCF)F |
| RTECS | VB1999050 |
| Peso molecular | 369.34 |
| Reaxy-Rn | 4300996 |
| Reaxys-RN_link_address | https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=4300996&ln= |
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →Full quality attributes and acceptance criteria for this grade.
View spec sheet →Taxonomy Tree
| Kingdom | Organic compounds |
|---|---|
| Superclass | Organoheterocyclic compounds |
| Clase | Quinolines and derivatives |
| Subclass | Quinoline carboxylic acids |
| Intermediate Tree Nodes | Not available |
| Direct Parent | Quinoline carboxylic acids |
| Alternative Parents | N-arylpiperazines Fluoroquinolones Aminoquinolines and derivatives Hydroquinolones Haloquinolines Hydroquinolines Pyridinecarboxylic acids Dialkylarylamines N-methylpiperazines Aryl fluorides Benzenoids Vinylogous amides Heteroaromatic compounds Trialkylamines Amino acids Azacyclic compounds Carboxylic acids Monocarboxylic acids and derivatives Organic oxides Alkyl fluorides Organofluorides Organopnictogen compounds Organooxygen compounds Hydrocarbon derivatives |
| Molecular Framework | Aromatic heteropolycyclic compounds |
| Substituents | Quinoline-3-carboxylic acid - Fluoroquinolone - N-arylpiperazine - Aminoquinoline - Haloquinoline - Dihydroquinolone - Dihydroquinoline - Pyridine carboxylic acid - Pyridine carboxylic acid or derivatives - Tertiary aliphatic/aromatic amine - Dialkylarylamine - N-methylpiperazine - N-alkylpiperazine - Aryl fluoride - Aryl halide - 1,4-diazinane - Piperazine - Pyridine - Benzenoid - Vinylogous amide - Heteroaromatic compound - Tertiary aliphatic amine - Amino acid - Amino acid or derivatives - Tertiary amine - Azacycle - Carboxylic acid derivative - Monocarboxylic acid or derivatives - Carboxylic acid - Organic nitrogen compound - Organopnictogen compound - Organic oxygen compound - Amine - Organic oxide - Organohalogen compound - Alkyl halide - Alkyl fluoride - Organofluoride - Organonitrogen compound - Organooxygen compound - Hydrocarbon derivative - Aromatic heteropolycyclic compound |
| Descripción | This compound belongs to the class of organic compounds known as quinoline carboxylic acids. These are quinolines in which the quinoline ring system is substituted by a carboxyl group at one or more positions. |
| External Descriptors | quinolines - fluoroquinolone antibiotic |
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Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Fecha | Articulo |
|---|---|---|---|
| Certificate of Analysis | Nov 10, 2022 | F114259 |
| Peso molecular | 369.340 g/mol |
|---|---|
| XLogP3 | -0.100 |
| Hydrogen Bond Donor Count | 1 |
| Hydrogen Bond Acceptor Count | 9 |
| Rotatable Bond Count | 4 |
| Exact Mass | 369.13 Da |
| Monoisotopic Mass | 369.13 Da |
| Topological Polar Surface Area | 64.099 Ų |
| Heavy Atom Count | 26 |
| Formal Charge | 0 |
| Complexity | 595.000 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| The total count of all stereochemical bonds | 0 |
| Covalently-Bonded Unit Count | 1 |
| 1. Qi Pu, Lu Zhang, Nengsheng Ye, Yuhong Xiang. (2023) Lanthanide coordination carbon quantum dots construct a ratiometric fluorescent sensor for the detection of norfloxacin in milk. DYES AND PIGMENTS, [PMID:] [10.1016/j.dyepig.2023.111815] |
| 2. Guangli Li, Xuan Wan, Yonghui Xia, Du Tuo, Xiaoman Qi, Tianyu Wang, Mohammad Mehmandoust, Nevin Erk, Quanguo He, Qing Li. (2023) Lamellar α-Zirconium Phosphate Nanoparticles Supported on N-Doped Graphene Nanosheets as Electrocatalysts for the Detection of Levofloxacin. ACS Applied Nano Materials, [PMID:] [10.1021/acsanm.3c03162] |
| 3. Changxing Wang, Feifei Qin, Siyuan Tang, Xiameng Li, Tingting Li, Guoqiang Guo, Chenjie Gu, Xu Wang, Da Chen. (2023) Construction of graphene quantum dots ratiometric fluorescent probe by intermolecular electron transfer effect for intelligent and real-time visual detection of ofloxacin and its L-isomer in daily drink. FOOD CHEMISTRY, [PMID:36724609] [10.1016/j.foodchem.2023.135514] |
| 4. Zhenyu Lu, Gongke Li, Yufei Hu. (2022) A Tb3+ functionalized triazine-porous organic framework as a ratiometric fluorescent sensor for determination of ciprofloxacin in aquatic products. NEW JOURNAL OF CHEMISTRY, 46 (40): (19153-19160). [PMID:] [10.1039/D2NJ03657F] |
| 5. Boqiang Gao, Yu Pan, Hu Yang. (2022) Enhanced photo-Fenton degradation of fluoroquinolones in water assisted by a 3D composite sponge complexed with a S-scheme MoS2/Bi2S3/BiVO4 ternary photocatalyst. APPLIED CATALYSIS B-ENVIRONMENTAL, [PMID:] [10.1016/j.apcatb.2022.121580] |
| 6. Boqiang Gao, Koukou Tao, Zhonghua Xi, Mayyada M.H. El-Sayed, Tamer Shoeib, Hu Yang. (2022) Fabrication of 3D lignosulfonate composited sponges impregnated by BiVO4/polyaniline/Ag ternary photocatalyst for synergistic adsorption-photodegradation of fluoroquinolones in water. CHEMICAL ENGINEERING JOURNAL, [PMID:] [10.1016/j.cej.2022.137282] |
| 7. Jin'ai Chen, Yuting Jin, Taotao Ren, Shuo Wang, Xianghong Wang, Fuyuan Zhang, Yiwei Tang. (2022) A novel terbium (III) and aptamer-based probe for label-free detection of three fluoroquinolones in honey and water samples. FOOD CHEMISTRY, [PMID:35334319] [10.1016/j.foodchem.2022.132751] |
| 8. Huikai Shao, Haibo Zhou, Tingting Zhang, Xianglong Zhao, Zhengjin Jiang, Qiqin Wang. (2018) Preparation of molecularly imprinted hybrid monoliths for the selective detection of fluoroquinolones in infant formula powders. JOURNAL OF CHROMATOGRAPHY A, [PMID:30587346] [10.1016/j.chroma.2018.12.038] |
| 9. Suyu Ren, Jing Tao, Feng Tan, Ying Cui, Xiaona Li, Jingwen Chen, Xin He, Yi Wang. (2018) Diffusive gradients in thin films based on MOF-derived porous carbon binding gel for in-situ measurement of antibiotics in waters. SCIENCE OF THE TOTAL ENVIRONMENT, [PMID:30029123] [10.1016/j.scitotenv.2018.07.013] |
| 10. Hua Jianhao, Jiao Yang, Wang Meng, Yang Yaling. (2018) Determination of norfloxacin or ciprofloxacin by carbon dots fluorescence enhancement using magnetic nanoparticles as adsorbent. MICROCHIMICA ACTA, 185 (2): (1-9). [PMID:29594473] [10.1007/s00604-018-2685-x] |
| 11. Fengliang Wang, Yiping Feng, Ping Chen, Yingfei Wang, Yuehan Su, Qianxin Zhang, Yongqin Zeng, Zhijie Xie, Haijin Liu, Yang Liu, Wenying Lv, Guoguang Liu. (2018) Photocatalytic degradation of fluoroquinolone antibiotics using ordered mesoporous g-C3N4 under simulated sunlight irradiation: Kinetics, mechanism, and antibacterial activity elimination. APPLIED CATALYSIS B-ENVIRONMENTAL, [PMID:] [10.1016/j.apcatb.2018.01.024] |
| 12. Yingfei Wang, Fengliang Wang, Yiping Feng, Zhijie Xie, Qianxin Zhang, Xiaoyu Jin, Haijin Liu, Yang Liu, Wenying Lv, Guoguang Liu. (2017) Facile synthesis of carbon quantum dots loaded with mesoporous g-C3N4 for synergistic absorption and visible light photodegradation of fluoroquinolone antibiotics. DALTON TRANSACTIONS, 47 (4): (1284-1293). [PMID:29299582] [10.1039/C7DT04360K] |
| 13. Xuanping Tan, Shaopu Liu, Yizhong Shen, Youqiu He, Yusha Liu, Jidong Yang. (2014) Glutathione-capped CdTe quantum dots for the determination of fleroxacin with dual-wavelength fluorescence signals. Analytical Methods, 6 (13): (4860-4866). [PMID:] [10.1039/C4AY00860J] |
| 14. Tianyu Wang, Yonghui Xia, Xuan Wan, Yafeng Zhang, Nayu Chen, Yuan Jin, Guangli Li. (2024) A facile and efficient voltammetric sensor for marbofloxacin detection based on zirconium-based metal-organic framework UiO-66/nitrogen-doped graphene nanocomposite. MICROCHEMICAL JOURNAL, [PMID:] [10.1016/j.microc.2024.110673] |
| 15. Qi Pu, Chumeng Wang, Xinyue Yin, Nengsheng Ye, Lu Zhang, Yuhong Xiang. (2024) A ratiometric fluorescent dark box and smartphone integrated portable sensing platform based on hydrogen bonding induction for on-site determination of enrofloxacin. FOOD CHEMISTRY, [PMID:38823143] [10.1016/j.foodchem.2024.139876] |
| 16. Shuting Shi, Chuanqin Zhou, Aiting Chen, Nana Tang, Kun Wan, Youwei Jiang, Jun Liu, Quanguo He, Li Cao. (2024) Bi2MoO6/MWCNTs-COOH/GCE electrochemical probe for ultrasensitively and selectively detecting antibiotic norfloxacin. CHEMOSPHERE, [PMID:39168389] [10.1016/j.chemosphere.2024.143139] |
| 17. Tianyu Wang, Wenyan Guo, Yonghui Xia, Yuefang Zhu, Li Chen, Yafeng Zhang, Guangli Li. (2024) Bimetallic UiO-66(Zr/Ce) MOF encapsulated reduced graphene oxide nanocomposite for voltametric detection of trace Lomefloxacin residues in milk. JOURNAL OF FOOD COMPOSITION AND ANALYSIS, [PMID:] [10.1016/j.jfca.2024.107086] |
| 18. Xiuzhen Wei, Zelong Chen, Liangliang Xu, Yue Li, Xuekang Zhang, Xianghao Zhang, Qinghua Zhou, Meilan Pan. (2024) Engineering Brønsted acid sites for enhanced nonradical pathways in antibiotic contaminant degradation. CHEMICAL ENGINEERING JOURNAL, [PMID:] [10.1016/j.cej.2024.157225] |
| 19. Wenrui Li, Yike Dang, Ruihong Wang, Weizhong Jin, Xiangli Chen, Yafei Zhai, Zhuoqun Su, Guoliang Li. (2024) Fabrication of magnetic functionalized layered double hydroxide nanomaterials for detecting trace fluoroquinolones residues in meat integrated with HPLC-MS/MS. JOURNAL OF FOOD COMPOSITION AND ANALYSIS, [PMID:] [10.1016/j.jfca.2024.106672] |
| 20. Fuhua Wei, Yan Wang, Qinhui Ren, Qin Zhang, Hongliang Chen, Zhao Liang. (2025) Preparation of Co/Cr-MOFs for efficient removal of fleroxacin and Rhodamine B. Green Processing and Synthesis, 14 (1): [PMID:] [10.1515/gps-2024-0195] |
| 21. Ruijie Tang, Lingfei Li, Yaowei Zhu, Minghui Zhan, Jun Zhao, Changlong Jiang, Bianhua Liu. (2025) Ratiometric fluorescent sensor for sensitive visualization of full-spectrum fluoroquinolone antibiotic residues in the environment. MICROCHEMICAL JOURNAL, [PMID:] [10.1016/j.microc.2025.113260] |
| 22. Yanping He, Peixuan Li, Xin Zhao, Dongmei Wang, Fuqiang Zhang. (2025) CoOOH-based colorimetric aptasensor with dual cascade amplification for ultrasensitive monitoring of fleroxacin in honey. FOOD CONTROL, [PMID:] [10.1016/j.foodcont.2025.111538] |
| 23. Shuyuan Guo, Miao Liu, Hanlin Liu, Jingru Mao, Yongfeng Zou, Li-Peng Sun, Yan Huang, Dandan Sun, Jie Ma. (2025) A reflective microfiber biosensor for monitoring of trace flumequine residues enhanced by europium-incorporated covalent organic framework. MICROCHEMICAL JOURNAL, [PMID:] [10.1016/j.microc.2025.114929] |
| 24. Fenglan Li, Qingyun Lai, Luying Chen, Junyang Zhuang. (2025) Ratiometric fluorescent sensor based on MOF for the detection of levofloxacin. MICROCHEMICAL JOURNAL, [PMID:] [10.1016/j.microc.2025.115179] |
| 25. Guangli Li, Yafeng Zhang, Rui Zhu, Zian Liu, Yuan Jin, Nanke Ma, Xuliang He. (2025) An efficient electrochemical sensor based on ZIF-8 MOF-derived N-containing porous carbon supported Fe3O4 nanoparticles for sensitive detection of ciprofloxacin residues in foods. MICROCHEMICAL JOURNAL, [PMID:] [10.1016/j.microc.2025.115415] |
| 26. Lili Lian, Xinyang Zhang, Jie Hao, Jinyi Lv, Xiyue Wang, Bo Zhu, Dawei Lou. (2018) Magnetic solid-phase extraction of fluoroquinolones from water samples using titanium-based metal-organic framework functionalized magnetic microspheres. JOURNAL OF CHROMATOGRAPHY A, [PMID:30352707] [10.1016/j.chroma.2018.10.019] |
| 27. Xiaoman Qi, Yonghui Xia, Jingtao Wu, Xuan Wan, Tianyu Wang, Qing Li, Guangli Li. (2025) Robust determination of marbofloxacin based on bimetallic Au@Ag nanoparticle-decorated black phosphorus nanosheets supported molecularly imprinted polymer film. Materials Today Chemistry, [PMID:] [10.1016/j.mtchem.2025.102687] |
| 28. Guangxin Yang, Jingru Zhang, Junyu Zhang, Peng Wang, Wei Xia, Jun Wang, Xiaosheng Shen, Cong Kong. (2025) Utilization of wolfberry biomass waste-derived biochar as an efficient solid-phase extraction material for antibiotic detection in aquatic products. FOOD CHEMISTRY, [PMID:40617214] [10.1016/j.foodchem.2025.145390] |
| 29. Jiaxuan Liu, Wensi Ma, Xinyue Huang, Lei Jiang, Lin Yuan, Xiuling Ji, Yujiao Tu. (2025) Rapeseed oil residue-based fluorescent probes for bifunctional detection of Hg2+ and aureomycin hydrochloride. MICROCHEMICAL JOURNAL, [PMID:] [10.1016/j.microc.2025.114165] |
| 30. Nanke Ma, Anqi Wei, Yajie Wang, Yafeng Zhang, Yuan Jin, Guangli Li, Xuliang He. (2025) Hierarchical α-zirconium phosphate/reduced graphene oxide nanocomposite for sensitive determination of fleroxacin. JOURNAL OF FOOD COMPOSITION AND ANALYSIS, [PMID:] [10.1016/j.jfca.2025.108413] |
| 31. Shuanghuan Gu, Sen Wang, Yongju Zhang, Zhixiang Xu, Longhua Xu. (2025) A ternary AuNP/NiFe-LDH/MWCNT heterostructure enhanced electrochemical biomimetic sensor for sensitive detection of enrofloxacin in aquatic foods. FOOD CHEMISTRY, [PMID:41205465] [10.1016/j.foodchem.2025.146940] |
| 32. Fuhua Wei, Anhui Huang, Qinhui Ren, Min Li, Wei Shang, Diaodiao Zhang, Zhao Liang. (2025) Preparation of GO/Cu/Cr-MOF Composite and Efficient Removal of Fleroxacin and Levofloxacin. APPLIED ORGANOMETALLIC CHEMISTRY, 40 (1): (e70473). [PMID:] [10.1002/aoc.70473] |