Fluconazole mesylate , CAS No.159532-41-9

CAS: 159532-41-9 Cat. No.: F1419212 PubChem CID: 17785855

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

Descripción general

Fluconazole (mesylate) is a triazole antifungal drug used in the treatment and prevention of superficial and systemic fungal infections.Target: Antifungal Fluconazole (mesylate) is the mesylate salt form of fluconazole, which is a triazole antifungal intended for oral treatment of superficial and systemic mycoses. In tests done in standard mycological media, the compound had minimal inhibitory concentrations against pathogenic Candida species that were usually in excess of 100 mg/l. Fluconazole inhibited branching and hyphal development in C. albicans at concentrations as low as 10(-6) M (0.3 mg/l), but miconazole and ketoconazole were still active in these tests at concentrations 100 times lower than this. Oral fluconazole was not associated with a significantly increased risk of birth defects overall or of 14 of the 15 specific birth defects of previous concern. Fluconazole exposure may confer an increased risk of tetralogy of Fallot. Fluconazole is predicted to be ineffective against Cryptococcus gattii in the koala as a sole therapeutic agent administered at 10 mg/kg p.o. every 12 h.Clinical indications: Balanitis; Candida infection ; Cryptococcus infection ; Cryptococcus neoformans meningitis; Dermatomycosis; Female genital tract infection ; Fungal infection; Fungal respiratory tract infection ; Fungal urinary tract infection ; Prophylaxis; Tinea capitis; Tinea corporis; Tinea cruris; Tinea pedis.Toxicity: Symptoms of overdose include hallucinations and paranoid behavior.

Specifications

Condiciones de almacenamiento de almacenamiento

Store at -20°C

Enviado en

Ice chest + Ice pads

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Nombres e identificadores

• Sonrisas canónicas: CS(=O)(=O)O.C1=CC(=C(C=C1F)F)C(CN2C=NC=N2)(CN3C=NC=N3)O
• IUPAC Name: 2-(2,4-difluorophenyl)-1,3-bis(1,2,4-triazol-1-yl)propan-2-ol;methanesulfonic acid
• InChIKey: DWJUZHMCPBPNFH-UHFFFAOYSA-N
• INCHI: 1S/C13H12F2N6O.CH4O3S/c14-10-1-2-11(12(15)3-10)13(22,4-20-8-16-6-18-20)5-21-9-17-7-19-21;1-5(2,3)4/h1-3,6-9,22H,4-5H2;1H3,(H,2,3,4)
• Isómeros SMILES: CS(=O)(=O)O.C1=CC(=C(C=C1F)F)C(CN2C=NC=N2)(CN3C=NC=N3)O
• CAS alternativo: 159532-41-9
• PubChem CID: 17785855