Determine the necessary mass, volume, or concentration for preparing a solution.
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Moligand™, ≥98% Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Cited in 18 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Fluocinolone Acetonide is a corticosteroid that binds to the cytosolic glucocorticoid receptor.
A synthetic glucocorticoid VEGF inhibitor.
| ALogP | 2.5 |
|---|
| Pubchem Sid | 504751029 |
|---|---|
| Pubchem Sid Url | https://pubchem.ncbi.nlm.nih.gov/substance/504751029 |
| Sonrisas canónicas | CC1(OC2CC3C4CC(C5=CC(=O)C=CC5(C4(C(CC3(C2(O1)C(=O)CO)C)O)F)C)F)C |
| IUPAC Name | (1S,2S,4R,8S,9S,11S,12R,13S,19S)-12,19-difluoro-11-hydroxy-8-(2-hydroxyacetyl)-6,6,9,13-tetramethyl-5,7-dioxapentacyclo[10.8.0.02,9.04,8.013,18]icosa-14,17-dien-16-one |
| InChIKey | FEBLZLNTKCEFIT-VSXGLTOVSA-N |
| INCHI | 1S/C24H30F2O6/c1-20(2)31-19-9-13-14-8-16(25)15-7-12(28)5-6-21(15,3)23(14,26)17(29)10-22(13,4)24(19,32-20)18(30)11-27/h5-7,13-14,16-17,19,27,29H,8-11H2,1-4H3/t13-,14-,16-,17-,19+,21-,22-,23-,24+/m0/s1 |
| Isómeros SMILES | C[C@]12C[C@@H]([C@]3([C@H]([C@@H]1C[C@@H]4[C@]2(OC(O4)(C)C)C(=O)CO)C[C@@H](C5=CC(=O)C=C[C@@]53C)F)F)O |
| WGK Alemania | 3 |
| RTECS | TU3830000 |
| Peso molecular | 452.49 |
| Reaxy-Rn | 37811598 |
| Reaxys-RN_link_address | https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=37811598&ln= |
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →Full quality attributes and acceptance criteria for this grade.
View spec sheet →Taxonomy Tree
| Kingdom | Organic compounds |
|---|---|
| Superclass | Lipids and lipid-like molecules |
| Clase | Steroids and steroid derivatives |
| Subclass | Hydroxysteroids |
| Intermediate Tree Nodes | Not available |
| Direct Parent | 21-hydroxysteroids |
| Alternative Parents | Gluco/mineralocorticoids, progestogins and derivatives 20-oxosteroids 11-beta-hydroxysteroids 3-oxo delta-1,4-steroids Halogenated steroids Delta-1,4-steroids Ketals 1,3-dioxolanes Alpha-hydroxy ketones Secondary alcohols Cyclic alcohols and derivatives Cyclic ketones Fluorohydrins Oxacyclic compounds Organic oxides Alkyl fluorides Primary alcohols Hydrocarbon derivatives Organofluorides |
| Molecular Framework | Aliphatic heteropolycyclic compounds |
| Substituents | Progestogin-skeleton - 21-hydroxysteroid - 20-oxosteroid - Pregnane-skeleton - 3-oxo-delta-1,4-steroid - 3-oxosteroid - 9-halo-steroid - 6-halo-steroid - Halo-steroid - Oxosteroid - 11-beta-hydroxysteroid - 11-hydroxysteroid - Delta-1,4-steroid - Ketal - Alpha-hydroxy ketone - Cyclic alcohol - Meta-dioxolane - Cyclic ketone - Secondary alcohol - Fluorohydrin - Halohydrin - Ketone - Organoheterocyclic compound - Acetal - Oxacycle - Organofluoride - Organic oxygen compound - Hydrocarbon derivative - Organooxygen compound - Organic oxide - Carbonyl group - Primary alcohol - Alkyl fluoride - Alcohol - Organohalogen compound - Alkyl halide - Aliphatic heteropolycyclic compound |
| Descripción | This compound belongs to the class of organic compounds known as 21-hydroxysteroids. These are steroids carrying a hydroxyl group at the 21-position of the steroid backbone. |
| External Descriptors | organic heteropentacyclic compound - 11beta-hydroxy steroid - glucocorticoid - cyclic ketal - 20-oxo steroid - fluorinated steroid - 3-oxo-Delta(1),Delta(4)-steroid - 21-hydroxy steroid |
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Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Fecha | Articulo |
|---|---|---|---|
| Certificate of Analysis | Jun 09, 2026 | F129244 | |
| Certificate of Analysis | Jun 09, 2026 | F129244 | |
| Certificate of Analysis | Jun 09, 2026 | F129244 | |
| Certificate of Analysis | Jun 09, 2026 | F129244 | |
| Certificate of Analysis | May 28, 2026 | F129244 | |
| Certificate of Analysis | Apr 02, 2026 | F129244 | |
| Certificate of Analysis | Jun 09, 2025 | F129244 | |
| Certificate of Analysis | May 12, 2022 | F129244 |
| Solubilidad | DMSO 90 mg/mL Water Ethanol 12 mg/mL |
|---|---|
| Punto de fusión (°C) | 267-269°C |
| Peso molecular | 452.500 g/mol |
| XLogP3 | 2.500 |
| Hydrogen Bond Donor Count | 2 |
| Hydrogen Bond Acceptor Count | 8 |
| Rotatable Bond Count | 2 |
| Exact Mass | 452.201 Da |
| Monoisotopic Mass | 452.201 Da |
| Topological Polar Surface Area | 93.100 Ų |
| Heavy Atom Count | 32 |
| Formal Charge | 0 |
| Complexity | 960.000 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 9 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| The total count of all stereochemical bonds | 0 |
| Covalently-Bonded Unit Count | 1 |
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| 2. Xiaoxuan Zhou, Tao Liu, Shengyi Zhang, Bo Kang, Xu Duan, Yuanyuan Yan, Leiyu Feng, Yinguang Chen. (2022) Metagenomic insight of fluorene-boosted sludge acidogenic fermentation: Metabolic transformation of amino acids and monosaccharides. SCIENCE OF THE TOTAL ENVIRONMENT, [PMID:36587690] [10.1016/j.scitotenv.2022.161122] |
| 3. Yangjie LI, Jiaying HUANG, Jihui FANG, Zhiye HUANG. (2022) [Fast screening and confirmation of 73 common prohibited compounds in cosmetics by ultra performance liquid chromatography-quadrupole-time-of-flight high resolution mass spectrometry].. Chinese Journal of Chromatography, 40 (5): (433-442). [PMID:35478002] [10.3724/sp.j.1123.2021.09010] |
| 4. Yue Cai, Binbin Yuan, Xiaoyue Ma, Guodong Fang, Dongmei Zhou, Juan Gao. (2022) Foliar application of SiO2 and ZnO nanoparticles affected polycyclic aromatic hydrocarbons uptake of Amaranth (Amaranthus tricolor L.): A metabolomics and typical statistical analysis. SCIENCE OF THE TOTAL ENVIRONMENT, [PMID:35429559] [10.1016/j.scitotenv.2022.155258] |
| 5. Yingnan Liu, Wanqi Jiang, Zan Yang, Fei Tong, Lei Wang, Lu Zhu, Zhenyu Yu, Mingming Zheng, Yaqing Xiao, Yibin Zhou. (2022) Intelligent biogenic amine-responsive fluorescent label for visual and real-time monitoring of seafood freshness. FOOD CHEMISTRY, [PMID:35436636] [10.1016/j.foodchem.2022.132963] |
| 6. Jiayang Zhang, Xiwen Ma, Xueping Dang, Huaixia Chen, Yuling Hu. (2021) Adsorption mechanism of polycyclic aromatic hydrocarbons on polythiophene-graphene covalent complex and its analytical application in food contact materials. MICROCHEMICAL JOURNAL, [PMID:] [10.1016/j.microc.2021.106767] |
| 7. Xiao-Yong Liao, Xue-Gang Gong, Li-Li Zhang, Daniel P. Cassidy. (2021) Micro-distribution of arsenic and polycyclic aromatic hydrocarbons and their interaction in Pteris vittata L.. ENVIRONMENTAL POLLUTION, [PMID:33957513] [10.1016/j.envpol.2021.117250] |
| 8. He-Tao Bian, Gao-Hua Wang, Jun-Jie Huang, Liang Liang, Ling Xiao, Hui-Ling Wang. (2020) Scutellarin protects against lipopolysaccharide-induced behavioral deficits by inhibiting neuroinflammation and microglia activation in rats. INTERNATIONAL IMMUNOPHARMACOLOGY, [PMID:33182053] [10.1016/j.intimp.2020.106943] |
| 9. Youfang Huang, Yanyun Li, Qing Luo, Xiaojia Huang. (2020) One-step preparation of functional groups-rich graphene oxide and carbon nanotubes nanocomposite for efficient magnetic solid phase extraction of glucocorticoids in environmental waters. CHEMICAL ENGINEERING JOURNAL, [PMID:] [10.1016/j.cej.2020.126785] |
| 10. Yuan Hao, Yang Dezheng, Jia Zixian, Zhou Xiongfeng, Wang Hongli, Xu Qingnan, Wang Wenchun, Xu Yong. (2020) Activated Carbon Modified by Nanosecond Pulsed Discharge for Polycyclic Aromatic Hydrocarbons Detection. PLASMA CHEMISTRY AND PLASMA PROCESSING, 40 (6): (1539-1553). [PMID:] [10.1007/s11090-020-10114-x] |
| 11. Wei Zhang, Peipei Zhou, Wei Liu, Huili Wang, Xuedong Wang. (2020) Enhanced adsorption/extraction of five typical polycyclic aromatic hydrocarbons from meat samples using magnetic effervescent tablets composed of dicationic ionic liquids and NiFe2O4 nanoparticles. JOURNAL OF MOLECULAR LIQUIDS, [PMID:] [10.1016/j.molliq.2020.113682] |
| 12. Bian Hetao, Wang Gaohua, Huang Junjie, Liang Liang, Zheng Yage, Wei Yanyan, Wang Hui, Xiao Ling, Wang Huiling. (2020) Dihydrolipoic acid protects against lipopolysaccharide-induced behavioral deficits and neuroinflammation via regulation of Nrf2/HO-1/NLRP3 signaling in rat. Journal of Neuroinflammation, 17 (1): (1-13). [PMID:32450903] [10.1186/s12974-020-01836-y] |
| 13. Zuotian Wu, Gaohua Wang, Huiling Wang, Ling Xiao, Yanyan Wei, Can Yang. (2020) Fluoxetine exposure for more than 2 days decreases the neuronal plasticity mediated by CRMP2 in differentiated PC12 cells. BRAIN RESEARCH BULLETIN, [PMID:32070769] [10.1016/j.brainresbull.2020.02.007] |
| 14. Shutao Wang, Shiyu Liu, Xiange Che, Zhifang Wang, Jingkun Zhang, Deming Kong. (2019) Recognition of polycyclic aromatic hydrocarbons using fluorescence spectrometry combined with bird swarm algorithm optimization support vector machine. SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY, [PMID:31374351] [10.1016/j.saa.2019.117404] |
| 15. He Guo, Nan Jiang, Huijuan Wang, Kefeng Shang, Na Lu, Jie Li, Yan Wu. (2019) Enhanced catalytic performance of graphene-TiO2 nanocomposites for synergetic degradation of fluoroquinolone antibiotic in pulsed discharge plasma system. APPLIED CATALYSIS B-ENVIRONMENTAL, [PMID:] [10.1016/j.apcatb.2019.01.052] |
| 16. Yan Kang, Huijun Xie, Bo Li, Jian Zhang, Huu Hao Ngo, Wenshan Guo, Zizhang Guo, Qiang Kong, Shuang Liang, Jie Liu, Tingting Cheng, Liwei Zhang. (2018) Performance of constructed wetlands and associated mechanisms of PAHs removal with mussels. CHEMICAL ENGINEERING JOURNAL, [PMID:] [10.1016/j.cej.2018.09.152] |
| 17. Xiaofei Liu, Xin Lu, Yong Huang, Chengwei Liu, Shulin Zhao. (2013) Fe3O4@ionic liquid@methyl orange nanoparticles as a novel nano-adsorbent for magnetic solid-phase extraction of polycyclic aromatic hydrocarbons in environmental water samples. TALANTA, [PMID:24401423] [10.1016/j.talanta.2013.11.039] |
| 18. Hua Li, Likun Zhao, Chaoqi Chen, Hua Zhu, Xuhui Mao. (2025) Immobilizing polycyclic aromatic hydrocarbon degrading bacteria with gel microspheres for bioaugmentation remediation of soil in a surfactant-enhanced slurry bioreactor. Journal of Cleaner Production, [PMID:] [10.1016/j.jclepro.2025.146653] |
Our grade selection guide covers purity, stabilizer status, and application suitability for all variants in our catalog.
View Moligand™ grade guide →