Fluoromethyl 1,1,1,3,3,3-Hexafluoroisopropyl Ether - Moligand™, ≥98% , Potassium channel subfamily K member 2 opener, CAS No.28523-86-6, Potassium channel subfamily K member 2 opener

CAS: 28523-86-6 Cat. No.: F102164 Peso molecular: 200.05 Número EC: 643-089-7

GRADE & PURITY Moligand™, ≥98%

Synonyms

Petrem | SEVOFLURANE (USP IMPURITY) | Sevofluranum | CHEBI:9130 | N01AB08 | Sevocalm | SEVOFLURANE [USAN] | fluoromethyl hexafluoroisopropyl ether | NCGC00167421-01 | SEVOFLURANE [MART.] | DB01236 | F0691 | SEVOFLURANE (EP MONOGRAPH) | 38LVP0K73A | Bax 30

Storage

Store at 2-8°C

Shipped In

Wet ice

Specifications

Sinónimos

Petrem | SEVOFLURANE (USP IMPURITY) | Sevofluranum | CHEBI:9130 | N01AB08 | Sevocalm | SEVOFLURANE [USAN] | fluoromethyl hexafluoroisopropyl ether | NCGC00167421-01 | SEVOFLURANE [MART.] | DB01236 | F0691 | SEVOFLURANE (EP MONOGRAPH) | 38LVP0K73A | Bax 30

Especificaciones y pureza

Moligand™, ≥98%

Condiciones de almacenamiento de almacenamiento

Store at 2-8°C

Enviado en

Wet ice

Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.

Grado

Moligand™

Tipo de acción

POSITIVE MODULATOR

Mecanismo de acción

Potassium channel subfamily K member 2 opener

Pureza

≥98%

Propiedades del producto

• ALogP: 2.8

Nombres e identificadores

• Pubchem Sid: 504750854
• Pubchem Sid Url: https://pubchem.ncbi.nlm.nih.gov/substance/504750854
• Sonrisas canónicas: C(OC(C(F)(F)F)C(F)(F)F)F
• IUPAC Name: 1,1,1,3,3,3-hexafluoro-2-(fluoromethoxy)propane
• InChIKey: DFEYYRMXOJXZRJ-UHFFFAOYSA-N
• INCHI: 1S/C4H3F7O/c5-1-12-2(3(6,7)8)4(9,10)11/h2H,1H2
• Isómeros SMILES: C(OC(C(F)(F)F)C(F)(F)F)F
• WGK Alemania: 1
• RTECS: KO0737000
• Peso molecular: 200.05
• Reaxy-Rn: 2041023
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=2041023&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organic oxygen compounds
    • Clase Organooxygen compounds
      • Subclass Ethers

• Kingdom: Organic compounds
• Superclass: Organic oxygen compounds
• Clase: Organooxygen compounds
• Subclass: Ethers
• Intermediate Tree Nodes: Not available
• Direct Parent: Dialkyl ethers
• Alternative Parents: Organofluorides Hydrocarbon derivatives Alkyl fluorides
• Molecular Framework: Aliphatic acyclic compounds
• Substituents: Dialkyl ether - Hydrocarbon derivative - Organofluoride - Organohalogen compound - Alkyl halide - Alkyl fluoride - Aliphatic acyclic compound
• Descripción: This compound belongs to the class of organic compounds known as dialkyl ethers. These are organic compounds containing the dialkyl ether functional group, with the formula ROR', where R and R' are alkyl groups.
• External Descriptors: organofluorine compound - ether

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Objetivos asociados (no humanos)

Plasmodium falciparum (966862 Activities)

Explore this target

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mecanismos de acción

Propiedades químicas y físicas

• Sensibilidad: Heat sensitive
• Punto de ebullición (°C): 58°C
• Peso molecular: 200.050 g/mol
• XLogP3: 2.800
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 8
• Rotatable Bond Count: 2
• Exact Mass: 200.007 Da
• Monoisotopic Mass: 200.007 Da
• Topological Polar Surface Area: 9.200 Ų
• Heavy Atom Count: 12
• Formal Charge: 0
• Complexity: 121.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1

Referencias

1. Shan Jiang, Chonghe Wang, Jingyao Zhu, Xuezhu Huang.  (2021)  Regulation of glial cell-derived neurotrophic factor in sevoflurane-induced neuronal apoptosis by long non-coding RNA CDKN2B-AS1 as a ceRNA to adsorb miR-133.  American Journal of Translational Research,      [PMID:34150056] [PMID:34150056]