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Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Flupirtine hydrochloride (D 9998 hydrochloride) is a selective neuropotassium channel opener with analgesic activity. Flupirtine hydrochloride is used to inhibit a variety of pain conditions, including chronic musculoskeletal pain, migraines, and neuralgia. Flupirtine hydrochloride has antidepressant and antioxidant properties and may increase the analgesic effect in combination therapy with morphine. Flupirtine hydrochloride relieves abnormally increased muscle tension and has a muscle relaxant effect. Flupirtine hydrochloride is clinically superior to other drugs, such as tramadol and pantoxan, plus its side effects are better tolerated. Flupirtine hydrochloride has a significant effect on inhibiting neural hyperexcitability and therefore exhibits inhibitory potential in various pain states.
| Sonrisas canónicas | CCOC(=O)NC1=C(N=C(C=C1)NCC2=CC=C(C=C2)F)N.Cl |
|---|---|
| IUPAC Name | ethyl N-[2-amino-6-[(4-fluorophenyl)methylamino]pyridin-3-yl]carbamate;hydrochloride |
| InChIKey | WBAZQELGBFQHPE-UHFFFAOYSA-N |
| INCHI | 1S/C15H17FN4O2.ClH/c1-2-22-15(21)19-12-7-8-13(20-14(12)17)18-9-10-3-5-11(16)6-4-10;/h3-8H,2,9H2,1H3,(H,19,21)(H3,17,18,20);1H |
| Isómeros SMILES | CCOC(=O)NC1=C(N=C(C=C1)NCC2=CC=C(C=C2)F)N.Cl |
| CAS alternativo | 33400-45-2 |
| PubChem CID | 198127 |
| Términos de entrada MeSH | D 9998;D-9998;ethyl 2-amino-6-((p-fluorobenzyl)amino)-3-pyridinecarbamate;flupirtin maleate;flupirtine;flupirtine maleate (1:1);Katadolon |
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