Fmoc-Trp(Boc)-OH - ≥97% , CAS No.143824-78-6

CAS: 143824-78-6 Cat. No.: F116800 Peso molecular: 526.58 Beilstein Registry Number: 7698009 Número EC: 604-383-0

GRADE & PURITY ≥97%

Synonyms

MFCD00038176 | EN300-249916 | N- | Na-(((9H-fluoren-9-yl)methoxy)carbonyl)-1-(tert-butoxycarbonyl)-L-tryptophan | F0507 | N1-Boc-Nalpha-Fmoc-L-tryptophan | N-tert-Butoxycarbonyl-N-9-fluorenylmethoxycarbonyl-L-tryptophan | (2S)-3-{1-[(tert-butoxy)carbonyl]

Storage

Store at -20°C,Argon charged

Shipped In

Ice chest + Ice pads

Descripción general

Fmoc-Trp(Boc)-OH can be used for the synthesis of analogs of Glukagon-like peptide-1 (GLP-1) for the treatment of type 2 diabetes[1] and various peptides by Fmoc solid phase peptide synthesis (SPPS).

Specifications

Sinónimos

MFCD00038176 | EN300-249916 | N- | Na-(((9H-fluoren-9-yl)methoxy)carbonyl)-1-(tert-butoxycarbonyl)-L-tryptophan | F0507 | N1-Boc-Nalpha-Fmoc-L-tryptophan | N-tert-Butoxycarbonyl-N-9-fluorenylmethoxycarbonyl-L-tryptophan | (2S)-3-{1-[(tert-butoxy)carbonyl]

Especificaciones y pureza

≥97%

Condiciones de almacenamiento de almacenamiento

Store at -20°C, Argon charged

Enviado en

Ice chest + Ice pads

Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.

Pureza

≥97%

Nombres e identificadores

• Pubchem Sid: 504764970
• Pubchem Sid Url: https://pubchem.ncbi.nlm.nih.gov/substance/504764970
• Sonrisas canónicas: CC(C)(C)OC(=O)N1C=C(C2=CC=CC=C21)CC(C(=O)O)NC(=O)OCC3C4=CC=CC=C4C5=CC=CC=C35
• IUPAC Name: (2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-[1-[(2-methylpropan-2-yl)oxycarbonyl]indol-3-yl]propanoic acid
• InChIKey: ADOHASQZJSJZBT-SANMLTNESA-N
• INCHI: 1S/C31H30N2O6/c1-31(2,3)39-30(37)33-17-19(20-10-8-9-15-27(20)33)16-26(28(34)35)32-29(36)38-18-25-23-13-6-4-11-21(23)22-12-5-7-14-24(22)25/h4-15,17,25-26H,16,18H2,1-3H3,(H,32,36)(H,34,35)/t26-/m0/s1
• Isómeros SMILES: CC(C)(C)OC(=O)N1C=C(C2=CC=CC=C21)C[C@@H](C(=O)O)NC(=O)OCC3C4=CC=CC=C4C5=CC=CC=C35
• WGK Alemania: 3
• Peso molecular: 526.58
• Beilstein: 7698009
• Reaxy-Rn: 13169226
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=13169226&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Benzenoids
    • Clase Fluorenes

• Kingdom: Organic compounds
• Superclass: Benzenoids
• Clase: Fluorenes
• Subclass: Not available
• Intermediate Tree Nodes: Not available
• Direct Parent: Fluorenes
• Alternative Parents: Indolecarboxylic acids 3-alkylindoles Alpha amino acids and derivatives Pyrrole carboxylic acids and derivatives Substituted pyrroles Carbamate esters Heteroaromatic compounds Organic carbonic acids and derivatives Azacyclic compounds Monocarboxylic acids and derivatives Carboxylic acids Carbonyl compounds Hydrocarbon derivatives Organic oxides Organonitrogen compounds Organopnictogen compounds
• Molecular Framework: Aromatic heteropolycyclic compounds
• Substituents: Fluorene - Indolecarboxylic acid - Indolecarboxylic acid derivative - Alpha-amino acid or derivatives - 3-alkylindole - Indole - Indole or derivatives - Pyrrole-1-carboxylic acid or derivatives - Substituted pyrrole - Heteroaromatic compound - Carbamic acid ester - Pyrrole - Carbonic acid derivative - Carboxylic acid derivative - Carboxylic acid - Azacycle - Monocarboxylic acid or derivatives - Organoheterocyclic compound - Hydrocarbon derivative - Organic oxide - Organopnictogen compound - Organic oxygen compound - Carbonyl group - Organic nitrogen compound - Organonitrogen compound - Organooxygen compound - Aromatic heteropolycyclic compound
• Descripción: This compound belongs to the class of organic compounds known as fluorenes. These are compounds containing a fluorene moiety, which consists of two benzene rings connected through either a cyclopentane, cyclopentene, or cyclopenta-1,3-diene.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Propiedades químicas y físicas

• Sensibilidad: Moisture sensitive
• Rotación específica [α]: -20 ° (C=1, DMF)
• Punto de fusión (°C): 99 °C
• Peso molecular: 526.600 g/mol
• XLogP3: 6.000
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 6
• Rotatable Bond Count: 9
• Exact Mass: 526.21 Da
• Monoisotopic Mass: 526.21 Da
• Topological Polar Surface Area: 107.000 Ų
• Heavy Atom Count: 39
• Formal Charge: 0
• Complexity: 880.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 1
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1