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Folic acid , CAS No.F413155
Disponible para pedir
Synonyms
Folacin | Vitamin B9 | Vitamin M | Pteroylglutamic acid | Folate
Storage
Room temperature
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Why this grade
for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Storage & shipping
Room temperature Ships Check lot-specific COA for exact specifications.
Quality documents
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Literature proof
Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Descripción general
Information
Folic acid (Folacin, Vitamin B9, Vitamin M, Pteroylglutamic acid, Folate), a B vitamin, plays an important role in cell division and in the synthesis of amino acids and nucleic acids like DNA.
In vitro
Folic acid treatment induces dose-related increases in BRCA1 mRNA expression in HepG2, Huh-7D12, Hs578T, and JURKAT and in BRCA2 in HepG2, Hs578T, MCF7, and MDA-MB-157 cells. FA does not affect the corresponding normal cells or on any of the ovarian cell lines. Folic acid induces increased BRCA1 protein expression in Hs578T, but not HepG2 cells, whereas BRCA2 protein levels are undetectable. FA treatment does not alter DNA repair in liver-derived cells, whereas there are transient effects on breast-derived cells. There is no effect of FA treatment on BRCA1 or BRCA2 DNA methylation, although there is some variation in the methylation of specific CpG loci between some cell lines
Cell Research(from reference)
Concentrations：0, 25, 50, 75, or 100 nmol/L
Specifications
Sinónimos
Folacin | Vitamin B9 | Vitamin M | Pteroylglutamic acid | Folate
Condiciones de almacenamiento de almacenamiento
Room temperature
Propiedades del producto
| ALogP | -0.232 |
|---|---|
| hba_count | 7 |
| Recuento HBD | 4 |
| Enlace rotable | 9 |
Nombres e identificadores
| Sonrisas canónicas | NC1=NC(=O)C2=C(N1)N=CC(=N2)CNC3=CC=C(C=C3)C(=O)NC(CCC(O)=O)C(O)=O |
|---|---|
| Reaxy-Rn | 11328266 |
| Reaxys-RN_link_address | https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=11328266&ln= |
Documentation
📋 Safety Data Sheet (SDS)
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →✅ Certificate of Analysis (COA)
Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →🔬 Specification Sheet
Full quality attributes and acceptance criteria for this grade.
View spec sheet →Advanced Data
Certificados (CoA, COO, BSE/TSE y tabla de análisis)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:
Propiedades químicas y físicas
| DMSO (mg/ml) Solubilidad máxima | 2 |
|---|---|
| DMSO (mM) Solubilidad máxima | 4.531037608 |
| Agua (mg/ml) Solubilidad máxima | ＜1 |
Preguntas frecuentes y artículos
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