FR 900098 Sal monosódica - ≥95% , CAS No.73226-73-0

CAS: 73226-73-0 Cat. No.: F135679 Peso molecular: 219.11

GRADE & PURITY ≥95%

Synonyms

FR-900098 sal monosódica, >=97% (RMN) | SCHEMBL4433234 | Sal monosódica del ácido 3-(n-acetilhidroxiamino)-propilfosfónico | FR900098 | LCFXFDGYDKNWMD-UHFFFAOYSA-M | BDBM50459311 | FR 900098 sal monosódica | Hidrógeno sódico {3-[acetil(hidroxi)amino]propi

Storage

Almacenar a -20°C,cargado con argón

Shipped In

Hielera + almohadillas de hielo

Descripción general

El FR900098 sódico es un agente antipalúdico que inhibe la 1-deoxi-d-xilulosa-5-fosfato (DXP) reductoisomerasa. El FR900098 sódico no tiene toxicidad aguda significativa ni genotoxicidad, y no tiene la capacidad de causar rotura cromosómica o heterogeneidad. El FR900098 sódico no tiene efectos sobre los glóbulos rojos de la médula ósea en ratones NMRI

Specifications

Sinónimos

FR-900098 sal monosódica, >=97% (RMN) | SCHEMBL4433234 | Sal monosódica del ácido 3-(n-acetilhidroxiamino)-propilfosfónico | FR900098 | LCFXFDGYDKNWMD-UHFFFAOYSA-M | BDBM50459311 | FR 900098 sal monosódica | Hidrógeno sódico {3-[acetil(hidroxi)amino]propi

Especificaciones y pureza

≥95%

Mecanismos bioquímicos y fisiológicos

la 1-deoxi-D-xilulosa 5-fosfato reductoisomerasa (DXR) es una enzima que interviene en el primer paso de la vía del no mevalonato para la biosíntesis de isoprenoides en bacterias Gram negativas y Gram positivas, plantas y el parásito causante de la forma

Condiciones de almacenamiento de almacenamiento

Almacenar a -20°C, cargado con argón

Enviado en

Hielera + almohadillas de hielo

Tipo de acción

INHIBITOR

Pureza

≥95%

Nombres e identificadores

• Pubchem Sid: 504769511
• Pubchem Sid Url: https://pubchem.ncbi.nlm.nih.gov/substance/504769511
• Sonrisas canónicas: CC(=O)N(CCCP(=O)(O)[O-])O.[Na+]
• IUPAC Name: sodium;3-[acetyl(hydroxy)amino]propyl-hydroxyphosphinate
• InChIKey: LCFXFDGYDKNWMD-UHFFFAOYSA-M
• INCHI: 1S/C5H12NO5P.Na/c1-5(7)6(8)3-2-4-12(9,10)11;/h8H,2-4H2,1H3,(H2,9,10,11);/q;+1/p-1
• Isómeros SMILES: CC(=O)N(CCCP(=O)(O)[O-])O.[Na+]
• WGK Alemania: 3
• Peso molecular: 219.11
• Reaxy-Rn: 4614581
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=4614581&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organic acids and derivatives
    • Clase Organic phosphonic acids and derivatives
      • Subclass Organic phosphonic acids

• Kingdom: Organic compounds
• Superclass: Organic acids and derivatives
• Clase: Organic phosphonic acids and derivatives
• Subclass: Organic phosphonic acids
• Intermediate Tree Nodes: Not available
• Direct Parent: Organic phosphonic acids
• Alternative Parents: Acetohydroxamic acids Acetamides Organophosphorus compounds Organonitrogen compounds Organic sodium salts Organic oxides Hydrocarbon derivatives Carbonyl compounds Organic cations
• Molecular Framework: Aliphatic acyclic compounds
• Substituents: Organophosphonic acid - Acetamide - Acetohydroxamic acid - Hydroxamic acid - Carboxylic acid derivative - Organic alkali metal salt - Organic sodium salt - Organic oxide - Organic salt - Organophosphorus compound - Organooxygen compound - Organonitrogen compound - Organic oxygen compound - Organic nitrogen compound - Hydrocarbon derivative - Carbonyl group - Organic cation - Aliphatic acyclic compound
• Descripción: This compound belongs to the class of organic compounds known as organic phosphonic acids. These are organic compounds containing phosphonic acid.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Objetivos asociados (no humanos)

Staphylococcus aureus (210822 Activities)

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Acinetobacter (437 Activities)

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Escherichia coli (133304 Activities)

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Mycobacterium tuberculosis (203094 Activities)

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Enterococcus faecalis (29875 Activities)

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Plasmodium falciparum (966862 Activities)

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Bacillus anthracis (2936 Activities)

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Mecanismos de acción

Propiedades químicas y físicas

• Solubilidad: H2O: ≥20 mg/mL
• Sensibilidad: light sensitive
• Peso molecular: 219.110 g/mol
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 4
• Exact Mass: 219.027 Da
• Monoisotopic Mass: 219.027 Da
• Topological Polar Surface Area: 101.000 Ų
• Heavy Atom Count: 13
• Formal Charge: 0
• Complexity: 211.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 2

XLogP3