Galloflavin - Moligand™, ≥95%(HPLC) , CAS No.568-80-9

CAS: 568-80-9 Cat. No.: G133921 Peso molecular: 278.17 Número EC: 806-015-6

GRADE & PURITY Moligand™, ≥95%(HPLC)

Synonyms

MLS000737267 | 6,8,9,10-tetrahydroxypyrano[3,2-c]isochromene-2,3-dione | FD10492 | DTXSID80205354 | 3,8,9,10-tetrahydroxypyrano[3,2-c][2]benzopyran-2,6-dione | Pyrano[3,2-c][2]benzopyran-2,6-dione, 3,8,9,10-tetrahydroxy- | Z104473380 | AKOS027326692 | Gal

Storage

Protected from light,Store at -20°C,Argon charged

Shipped In

Ice chest + Ice pads

Descripción general

Galloflavin inhibits both the A and B isoforms of lactate dehydrogenase with Ki of 5.46 μM and 15.06 μM, respectively. Galloflavin is also a potential anticancer agent.

Specifications

Sinónimos

MLS000737267 | 6, 8, 9, 10-tetrahydroxypyrano[3, 2-c]isochromene-2, 3-dione | FD10492 | DTXSID80205354 | 3, 8, 9, 10-tetrahydroxypyrano[3, 2-c][2]benzopyran-2, 6-dione | Pyrano[3, 2-c][2]benzopyran-2, 6-dione, 3, 8, 9, 10-tetrahydroxy- | Z104473380 | AKOS027326692 | Gal

Especificaciones y pureza

Moligand™, ≥95%(HPLC)

Mecanismos bioquímicos y fisiológicos

Galloflavin is an inhibitor of lactate dehydrogenase (LDH). The compound blocks both isoforms of (LDH-A and -B) with Ki values of 5.5 and 15 mM, respectively. Inhibition of the glycolytic pathway by galloflavin induces oxidative stress and apoptosis in br

Condiciones de almacenamiento de almacenamiento

Protected from light, Store at -20°C, Argon charged

Enviado en

Ice chest + Ice pads

Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.

Grado

Moligand™

Nota

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

Pureza

≥95%(HPLC)

Nombres e identificadores

• Pubchem Sid: 504773355
• Pubchem Sid Url: https://pubchem.ncbi.nlm.nih.gov/substance/504773355
• Sonrisas canónicas: C1=C2C(=C3C(=CC(=C(O3)O)O)OC2=O)C(=C(C1=O)O)O
• IUPAC Name: 2,3,9,10-tetrahydroxypyrano[3,2-c]isochromene-6,8-dione
• InChIKey: UXHISTVMLJLECY-UHFFFAOYSA-N
• INCHI: 1S/C12H6O8/c13-4-1-3-7(9(16)8(4)15)10-6(19-11(3)17)2-5(14)12(18)20-10/h1-2,14-16,18H
• Isómeros SMILES: C1=C2C(=C3C(=CC(=C(O3)O)O)OC2=O)C(=C(C1=O)O)O
• WGK Alemania: 3
• Peso molecular: 278.17
• Reaxy-Rn: 36462593
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=36462593&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Phenylpropanoids and polyketides
    • Clase Isocoumarins and derivatives

• Kingdom: Organic compounds
• Superclass: Phenylpropanoids and polyketides
• Clase: Isocoumarins and derivatives
• Subclass: Not available
• Intermediate Tree Nodes: Not available
• Direct Parent: Isocoumarins and derivatives
• Alternative Parents: 2-benzopyrans Pyranones and derivatives 1-hydroxy-4-unsubstituted benzenoids Vinylogous acids Heteroaromatic compounds Lactones Cyclic ketones Polyols Oxacyclic compounds Organic oxides Hydrocarbon derivatives
• Molecular Framework: Aromatic heteropolycyclic compounds
• Substituents: Isocoumarin - 2-benzopyran - Benzopyran - 1-hydroxy-4-unsubstituted benzenoid - Pyranone - Benzenoid - Pyran - Heteroaromatic compound - Vinylogous acid - Cyclic ketone - Lactone - Oxacycle - Organoheterocyclic compound - Polyol - Organic oxygen compound - Organic oxide - Hydrocarbon derivative - Organooxygen compound - Aromatic heteropolycyclic compound
• Descripción: This compound belongs to the class of organic compounds known as isocoumarins and derivatives. These are polycyclic compounds containing an isochromane which bears a ketone at the carbon C1.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Propiedades químicas y físicas

• Sensibilidad: light sensitive
• Peso molecular: 278.170 g/mol
• XLogP3: -0.900
• Hydrogen Bond Donor Count: 4
• Hydrogen Bond Acceptor Count: 8
• Rotatable Bond Count: 0
• Exact Mass: 278.006 Da
• Monoisotopic Mass: 278.006 Da
• Topological Polar Surface Area: 134.000 Ų
• Heavy Atom Count: 20
• Formal Charge: 0
• Complexity: 729.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1