GRADE & PURITYAnimal Free?Animal-free — produced without animal-derived components to reduce contamination risk. Use in biomanufacturing and culture avoiding animal-origin material.Carrier Free?Carrier-free — supplied without added carrier protein/stabilizer. Use when carriers (e.g. BSA) would interfere with conjugation or sensitive assays.Recombinant?Recombinant — produced via recombinant expression for defined sequence and consistency. Use for reproducible, animal-free proteins of known origin.Validated?Validated grade — performance confirmed in defined applications before release. Use when you want documented assurance the reagent works as stated.ExactAb™?ExactAb™ — Aladdin's antibody line emphasizing precision and validated quality. Use for reliable, specificity-validated antibody applications.Low Endotoxin?Low-endotoxin grade — endotoxin reduced to low controlled levels. Use in sensitive biological work where high endotoxin would interfere.Azide Free?Azide-free — without sodium azide preservative. Use in conjugations, cell work, or assays where azide is toxic or inhibitory.≥90%(SDS-PAGE&SEC-HPLC)See COA
Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥90%(SDS-PAGE&SEC-HPLC), See COA Animal Free,Azide Free,Carrier Free,ExactAb™,Low Endotoxin,Recombinant,Validated for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
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Storage & shipping
Store at -80°C,Avoid repeated freezing and thawing Ships Dry ice packs + Cold packs Check lot-specific COA for exact specifications.
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Quality documents
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
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Literature proof
Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Descripción general
Glembatumumab vedotin (anti-GPNMB) is an ADC (antibody-drug conjugates (ADCs)) comprising a fully human IgG2 monoclonal antibody (CR011) directed against glycoprotein NMB (GPNMB) and conjugated to the potent tubulinbinding cytotoxic agent MMAE via a protease-sensitive vc linker. Glembatumumab vedotin (anti-GPNMB) has potent anticancer effects.
Specifications
Product Name
Glembatumumab vedotin (anti-GPNMB) - Primary antibody, specific to GPNMB, >90% (SDS-PAGE&SEC), Human IgG2SA, BINDING AGENT of Transmembrane glycoprotein NMB binding agent
BINDING AGENT of Transmembrane glycoprotein NMB binding agent
Isotipo
Human IgG2SA
Tipo de cadena ligera
kappa
SDS-PAGE
145.56 kDa
Método de purificación
Protein A purified
Pureza
>90% (SDS-PAGE&SEC)
Concentración
See COA
CAS
1182215-65-1
Almacenamiento y envío
Forma
Liquid
Condiciones de almacenamiento de almacenamiento
Store at -80°C,Avoid repeated freezing and thawing
Enviado en
Dry ice packs + Cold packs
Estabilidad y almacenamiento
Store at -80℃ for 24 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.
Imágenes
Glembatumumab vedotin (anti-GPNMB) (Ab175551) - ELISA Immobilized Recombinant SYDX-C076-huGPNMB-his protein at 2.0 μg/mL can bind Glembatumumab vedotin (anti-GPNMB) (Ab175551) with the EC50 of 13.88 ng/mL.
Glembatumumab vedotin (anti-GPNMB) (Ab175551) - SEC The purity of Glembatumumab vedotin (anti-GPNMB) (Ab175551) is more than 95% verified by HPLC.
Documentation
📋 Safety Data Sheet (SDS)
Comprehensive hazard, handling, storage, and regulatory compliance document.
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