10mM in DMSO for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Store at -80°C Ships Dry ice packs + Cold packs Check lot-specific COA for exact specifications.
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Cited in 3 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Information
Gliquidone Gliquidone (Glurenorm) is an ATP-sensitive K + channel antagonist with IC50 of 27.2 nM.
In vitro
In vivo
Gliquidone (0.1–1.0 μg per mouse i.c.v.) prevents antinociception produced by amitriptyline and clomipramine in a dose-dependent manner in male swiss albino mice. Gliquidone (0.06–16 μg per mouse, i.c.v.) antagonizes the antinociception induced by buprenorphine, morphine and methadone. Gliquidone (6 μg per mouse, i.c.v.) prevents the antinociception induced by clonidine (0.125 mg/kg, s.c.) and guanabenz (0.30 mg/kg, s.c.), while a lower dose of gliquidone (3 μg per mouse, i.c.v.) is ineffective. Glurenorm (10 mg/kg) given to the diabetic rats produces significant reductions in blood glucose, nonenzymatic glycosylation, and total protein in the lenses, and significantly increases in glutathione levels in the lenses.
Cell Data
cell lines：HT-29, HeLa, and PC3
Concentrations：
Incubation Time：
Powder Purity:≥99%
| Isómeros SMILES | CC1(C2=C(C=C(C=C2)OC)C(=O)N(C1=O)CCC3=CC=C(C=C3)S(=O)(=O)NC(=O)NC4CCCCC4)C |
|---|---|
| RTECS | DB1584250 |
| Peso molecular | 527.63 |
| Reaxy-Rn | 1559726 |
| Reaxys-RN_link_address | https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=1559726&ln= |
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →Full quality attributes and acceptance criteria for this grade.
View spec sheet →| Punto de fusión (°C) | 179 °C |
|---|
| 1. Zixian He, Zhiwei Liu, Haihuan Xie, Pengjie Luo, Xiangmei Li. (2023) An Ultrasensitive Lateral Flow Immunoassay Based on Metal-Organic Framework-Decorated Polydopamine for Multiple Sulfonylureas Adulteration in Functional Foods. Foods, 12 (3): (539). [PMID:36766067] [10.3390/foods12030539] |
| 2. Haihuan Xie, Yingying Li, Jin Wang, Yi Lei, Anastasios Koidis, Xiangmei Li, Xing Shen, Zhenlin Xu, Hongtao Lei. (2021) Broad-specific immunochromatography for simultaneous detection of various sulfonylureas in adulterated multi-herbal tea. FOOD CHEMISTRY, [PMID:34536782] [10.1016/j.foodchem.2021.131055] |
| 3. Jiankun Cao, Qing Jiang, Ruixian Li, Qian Xu, Hongli Li. (2019) Nanofibers mat as sampling module of direct analysis in real time mass spectrometry for sensitive and high-throughput screening of illegally adulterated sulfonylureas in antidiabetic health-care teas. TALANTA, [PMID:31357362] [10.1016/j.talanta.2019.06.066] |
