GLP-1 (7-37), Agonist of GLP-1 receptor, CAS No.106612-94-6, Agonist of GLP-1 receptor

CAS: 106612-94-6 Cat. No.: G287230 Peso molecular: 3355.71 PubChem CID: 16133830

GRADE & PURITY Moligand™, ≥95%

Descripción general

GLP-1(7-37) is an intestinal insulinotropic hormone that augments glucose induced insulin secretion.

Specifications

Product Name

GLP-1 (7-37), Agonist of GLP-1 receptor, CAS No.106612-94-6

Sinónimos

1450806-98-0 | AKOS025142102 | GLP-1 (7-37) | DTXSID50147676 | GLP-1(7-37) Acetate | GLP-1(7-37) acetate(106612-94-6 free base) | AC-8923 | F92802 | GLP-1 (7-37) peptide | CID 16133830

Grado

Moligand™

Especificaciones y pureza

Moligand™, ≥95%

Mecanismos bioquímicos y fisiológicos

Endogenous GLP-1 receptor ligand; bioactive and truncated form of GLP-1; insulinotropic hormone.

Secuencia

HAEGTFTSDVSSYLEGQAAKEFIAWLVKGRG

Tipo de acción

AGONIST

Mecanismo de acción

Agonist of GLP-1 receptor

CAS

106612-94-6

Tipo de molécula

Peptide

Almacenamiento y envío

Condiciones de almacenamiento de almacenamiento

Store at -20°C

Enviado en

Ice chest + Ice pads

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organic Polymers
    • Clase Polypeptides

• Kingdom: Organic compounds
• Superclass: Organic Polymers
• Clase: Polypeptides
• Subclass: Not available
• Intermediate Tree Nodes: Not available
• Direct Parent: Polypeptides
• Alternative Parents: Peptides Tyrosine and derivatives Phenylalanine and derivatives Arginine and derivatives Histidine and derivatives Pentacarboxylic acids and derivatives Glutamine and derivatives Glutamic acid and derivatives Aspartic acid and derivatives Isoleucine and derivatives Leucine and derivatives N-acyl-alpha amino acids Valine and derivatives Serine and derivatives Tryptamines and derivatives Alpha amino acid amides Alanine and derivatives 3-alkylindoles Amphetamines and derivatives Imidazolyl carboxylic acids and derivatives 1-hydroxy-2-unsubstituted benzenoids Aralkylamines Substituted pyrroles N-acyl amines Heteroaromatic compounds Secondary carboxylic acid amides Secondary alcohols Amino acids Primary carboxylic acid amides Guanidines Azacyclic compounds Carboximidamides Carboxylic acids Organic oxides Primary alcohols Hydrocarbon derivatives Imines Carbonyl compounds Monoalkylamines
• Molecular Framework: Aromatic heteropolycyclic compounds
• Substituents: Polypeptide - Alpha peptide - Tyrosine or derivatives - Arginine or derivatives - Phenylalanine or derivatives - Pentacarboxylic acid or derivatives - Histidine or derivatives - Glutamic acid or derivatives - Glutamine or derivatives - Isoleucine or derivatives - Aspartic acid or derivatives - Leucine or derivatives - Valine or derivatives - N-acyl-alpha amino acid or derivatives - N-acyl-alpha-amino acid - Alpha-amino acid amide - Triptan - Serine or derivatives - Alanine or derivatives - 3-alkylindole - Alpha-amino acid or derivatives - Amphetamine or derivatives - N-substituted-alpha-amino acid - Indole or derivatives - Indole - Imidazolyl carboxylic acid derivative - 1-hydroxy-2-unsubstituted benzenoid - Aralkylamine - Phenol - Fatty amide - Substituted pyrrole - Fatty acyl - N-acyl-amine - Monocyclic benzene moiety - Benzenoid - Imidazole - Pyrrole - Heteroaromatic compound - Azole - Amino acid or derivatives - Amino acid - Carboxamide group - Guanidine - Secondary carboxylic acid amide - Secondary alcohol - Primary carboxylic acid amide - Azacycle - Carboxylic acid derivative - Carboxylic acid - Organoheterocyclic compound - Carboximidamide - Primary alcohol - Organooxygen compound - Organic oxygen compound - Carbonyl group - Organonitrogen compound - Hydrocarbon derivative - Alcohol - Organic nitrogen compound - Primary amine - Organic oxide - Primary aliphatic amine - Amine - Imine - Aromatic heteropolycyclic compound
• Descripción: This compound belongs to the class of organic compounds known as polypeptides. These are peptides containing ten or more amino acid residues.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Objetivos asociados (humanos)

GLP1R Tclin Glucagon-like peptide 1 receptor (0 Activities)

Discover Target: GLP1R

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Información genética

• Alternate Names: 1450806-98-0 | AKOS025142102 | GLP-1 (7-37) | DTXSID50147676 | GLP-1(7-37) Acetate | GLP-1(7-37) acetate(106612-94-6 free base) | AC-8923 | F92802 | GLP-1 (7-37) peptide | CID 16133830
• Reference:
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Referencias

1. Ekaterina A. Litus, Marina P. Shevelyova, Alisa A. Vologzhannikova, Evgenia I. Deryusheva, Alina V. Chaplygina, Victoria A. Rastrygina, Andrey V. Machulin, Valeria D. Alikova, Aliya A. Nazipova, Maria E. Permyakova, Victor V. Dotsenko, Sergei E. Permyakov, Ekaterina L. Nemashkalova.  (2025)  Interaction Between Glucagon-like Peptide 1 and Its Analogs with Amyloid-β Peptide Affects Its Fibrillation and Cytotoxicity.  INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES,  26  (9): (4095).  [PMID:40362335] [10.3390/ijms26094095]