GRADE & PURITY 10mM in Water

Synonyms

Glycyl-L-leucine | EINECS 212-785-9 | 15-ketoeicosatetraenoic acid | AMY22216 | GLY-DL-LEU | (2S)-2-[(2-aminoacetyl)amino]-4-methylpentanoic acid | Gly-Leu | AF 2 | EN300-881493 | BDBM50188492 | L-Leucine, glycyl- | (S)-2-(2-Aminoacetamido)-4-methylpentan

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

Specifications

Sinónimos

Glycyl-L-leucine | EINECS 212-785-9 | 15-ketoeicosatetraenoic acid | AMY22216 | GLY-DL-LEU | (2S)-2-[(2-aminoacetyl)amino]-4-methylpentanoic acid | Gly-Leu | AF 2 | EN300-881493 | BDBM50188492 | L-Leucine, glycyl- | (S)-2-(2-Aminoacetamido)-4-methylpentan

Especificaciones y pureza

10mM in Water

Condiciones de almacenamiento de almacenamiento

Store at -80°C

Enviado en

Dry ice packs + Cold packs

Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.

Nombres e identificadores

• Sonrisas canónicas: CC(C)CC(C(=O)O)NC(=O)CN
• IUPAC Name: (2S)-2-[(2-aminoacetyl)amino]-4-methylpentanoic acid
• InChIKey: DKEXFJVMVGETOO-LURJTMIESA-N
• INCHI: 1S/C8H16N2O3/c1-5(2)3-6(8(12)13)10-7(11)4-9/h5-6H,3-4,9H2,1-2H3,(H,10,11)(H,12,13)/t6-/m0/s1
• Isómeros SMILES: CC(C)C[C@@H](C(=O)O)NC(=O)CN
• Peso molecular: 188.22
• Beilstein: 4453
• Reaxy-Rn: 1726293
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=1726293&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organic acids and derivatives
    • Clase Carboxylic acids and derivatives
      • Subclass Amino acids, peptides, and analogues

• Kingdom: Organic compounds
• Superclass: Organic acids and derivatives
• Clase: Carboxylic acids and derivatives
• Subclass: Amino acids, peptides, and analogues
• Intermediate Tree Nodes: Not available
• Direct Parent: Peptides
• Alternative Parents: Leucine and derivatives N-acyl-alpha amino acids Methyl-branched fatty acids Amino acids Propargyl-type 1,3-dipolar organic compounds Monocarboxylic acids and derivatives Carboxylic acids Carboximidic acids Organopnictogen compounds Organic oxides Monoalkylamines Hydrocarbon derivatives Carbonyl compounds
• Molecular Framework: Aliphatic acyclic compounds
• Substituents: Alpha peptide - Leucine or derivatives - N-acyl-alpha-amino acid - N-acyl-alpha amino acid or derivatives - Alpha-amino acid or derivatives - Branched fatty acid - Methyl-branched fatty acid - Fatty acyl - Fatty acid - Amino acid or derivatives - Amino acid - Carboximidic acid - Carboximidic acid derivative - Carboxylic acid - Monocarboxylic acid or derivatives - Organic 1,3-dipolar compound - Propargyl-type 1,3-dipolar organic compound - Organic oxide - Organic oxygen compound - Primary aliphatic amine - Amine - Organic nitrogen compound - Hydrocarbon derivative - Organonitrogen compound - Organooxygen compound - Organopnictogen compound - Primary amine - Carbonyl group - Aliphatic acyclic compound
• Descripción: This compound belongs to the class of organic compounds known as peptides. These are compounds containing an amide derived from two or more amino carboxylic acid molecules (the same or different) by formation of a covalent bond from the carbonyl carbon of one to the nitrogen atom of another.
• External Descriptors: dipeptide

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Objetivos asociados (humanos)

ACE Tclin Angiotensin-converting enzyme (1423 Activities)

Discover Target: ACE

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

SLC15A1 Tchem Oligopeptide transporter small intestine isoform (922 Activities)

Discover Target: SLC15A1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Objetivos asociados (no humanos)

Slc15a2 Oligopeptide transporter, kidney isoform (114 Activities)

Discover Target: Slc15a2

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Slc15a1 Solute carrier family 15 member 1 (124 Activities)

Discover Target: Slc15a1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mecanismos de acción

Propiedades químicas y físicas

• Rotación específica [α]: -35 ° (C=2, H2O)
• Punto de fusión (°C): 256°C
• Peso molecular: 188.220 g/mol
• XLogP3: -2.300
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 5
• Exact Mass: 188.116 Da
• Monoisotopic Mass: 188.116 Da
• Topological Polar Surface Area: 92.400 Ų
• Heavy Atom Count: 13
• Formal Charge: 0
• Complexity: 192.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 1
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1

Referencias

1. Yong-Yu Qi, Qian Gan, Ya-Xian Liu, Ya-Hong Xiong, Zong-Wan Mao, Xue-Yi Le.  (2018)  Two new Cu(II) dipeptide complexes based on 5-methyl-2-(2′-pyridyl)benzimidazole as potential antimicrobial and anticancer drugs: Special exploration of their possible anticancer mechanism.  EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY,      [PMID:29803995] [10.1016/j.ejmech.2018.05.023]

2. Guangxin Yuan, Yongbo Peng, Zhenghua Liu, Jieya Hong, Yao Xiao, Jialiang Guo, Norman W. Smith, Jacques Crommen, Zhengjin Jiang.  (2013)  A facile and efficient strategy to enhance hydrophilicity of zwitterionic sulfoalkylbetaine type monoliths.  JOURNAL OF CHROMATOGRAPHY A,      [PMID:23796416] [10.1016/j.chroma.2013.05.063]

3. Xueyan Zhu, Xianglong Zhao, Zhongkang Wang, Xiaoyuan Xie, Jincai Wang, Jianlong Liang, Zheng Liu, Tao Deng, Bin Yang, Jialiang Guo.  (2025)  Preparation of a Biomimetic Poly-Phosphatidylserine Monolithic Column for Immobilized Artificial Membrane Chromatography.  JOURNAL OF SEPARATION SCIENCE,  48  (3): (e70120).  [PMID:40114441] [10.1002/jssc.70120]