GMQ hydrochloride - ≥98% , CAS No.5361-15-9

CAS: 5361-15-9 Cat. No.: G274891 Peso molecular: 237.69 Número EC: 654-799-1 PubChem CID: 12253739

GRADE & PURITY ≥98%

Synonyms

SCHEMBL16908919 | 2-(4-methylquinazolin-2-yl)guanidine;hydrochloride | GMQ (hydrochloride) | 1-(4-methylquinazolin-2-yl)guanidine hydrochloride | AKOS024332817 | HY-107757 | NSC 403387 hydrochloride | 1-(4-methylquinazolin-2-yl)guanidinehydrochloride | N-

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

Descripción general

Store at +4°C. The product can be stored for up to 12 months.

Specifications

Sinónimos

SCHEMBL16908919 | 2-(4-methylquinazolin-2-yl)guanidine;hydrochloride | GMQ (hydrochloride) | 1-(4-methylquinazolin-2-yl)guanidine hydrochloride | AKOS024332817 | HY-107757 | NSC 403387 hydrochloride | 1-(4-methylquinazolin-2-yl)guanidinehydrochloride | N-

Especificaciones y pureza

≥98%

Mecanismos bioquímicos y fisiológicos

Selective ASIC3 channel activator at pH 7.4. Alters the pH dependence of ASIC1a and ASIC1b; does not affect the activation curve of ASIC2a. Competitive GABA A receptor antagonist (IC 50 = 390 nM). Shows nociceptive effects in vivo.

Condiciones de almacenamiento de almacenamiento

Store at -20°C

Enviado en

Ice chest + Ice pads

Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.

Tipo de acción

ACTIVATOR

Nota

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

Pureza

≥98%

Nombres e identificadores

• Pubchem Sid: 504767016
• Pubchem Sid Url: https://pubchem.ncbi.nlm.nih.gov/substance/504767016
• Sonrisas canónicas: CC1=NC(=NC2=CC=CC=C12)N=C(N)N.Cl
• IUPAC Name: 2-(4-methylquinazolin-2-yl)guanidine;hydrochloride
• InChIKey: VNPZWQRWOHFAPD-UHFFFAOYSA-N
• INCHI: 1S/C10H11N5.ClH/c1-6-7-4-2-3-5-8(7)14-10(13-6)15-9(11)12;/h2-5H,1H3,(H4,11,12,13,14,15);1H
• Isómeros SMILES: CC1=NC(=NC2=CC=CC=C12)N=C(N)N.Cl
• WGK Alemania: 3
• PubChem CID: 12253739
• Peso molecular: 237.69

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organoheterocyclic compounds
    • Clase Diazanaphthalenes
      • Subclass Benzodiazines
        • Level5 Quinazolines
          • Level6 Quinazolinamines

• Kingdom: Organic compounds
• Superclass: Organoheterocyclic compounds
• Clase: Diazanaphthalenes
• Subclass: Benzodiazines
• Intermediate Tree Nodes: Quinazolines
• Direct Parent: Quinazolinamines
• Alternative Parents: Pyrimidines and pyrimidine derivatives Benzenoids Heteroaromatic compounds Guanidines Propargyl-type 1,3-dipolar organic compounds Azacyclic compounds Hydrochlorides Hydrocarbon derivatives
• Molecular Framework: Aromatic heteropolycyclic compounds
• Substituents: Quinazolinamine - Benzenoid - Pyrimidine - Heteroaromatic compound - Guanidine - Azacycle - Organic 1,3-dipolar compound - Propargyl-type 1,3-dipolar organic compound - Organic nitrogen compound - Hydrocarbon derivative - Hydrochloride - Organonitrogen compound - Aromatic heteropolycyclic compound
• Descripción: This compound belongs to the class of organic compounds known as quinazolinamines. These are heterocyclic aromatic compounds containing a quianazoline moiety substituted by one or more amine groups.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Propiedades químicas y físicas

• Solubilidad: Soluble in DMSO to 50 mM and in water to 5 mM (with warming)
• Peso molecular: 237.690 g/mol
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 1
• Exact Mass: 237.078 Da
• Monoisotopic Mass: 237.078 Da
• Topological Polar Surface Area: 90.200 Ų
• Heavy Atom Count: 16
• Formal Charge: 0
• Complexity: 248.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 2

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