🌎 Ship to: United States
Toggle Nav
Cart
Buscar
Envío en el mismo día para todos los artículos en stock.
Búsqueda avanzada
Pedido rápido SDS CoA
Menú
Cuenta
Configuración
྾
224,000+ productos de investigación · Triple ISO certified · COA & SDS Disponible para cada producto · Same-day shipping on in-stock items

GN 44028 - ≥98%(HPLC) , CAS No.1421448-26-1

CAS: 1421448-26-1 Cat. No.: G288045 Peso molecular: 305.33
COA
GN 44028 - ≥98%(HPLC) CAS No(1421448-26-1) by Aladdin Scientific
Disponible para pedir
GRADE & PURITY ≥98%(HPLC)
Synonyms
N-(2,3-Dihydro-1,4-benzodioxin-6-yl)-1,4-dihydroindeno[1,2-c]pyrazol-3-amine | GN44028
Storage
Store at -20°C,Argon charged
Shipped In
Ice chest + Ice pads
★
 ·  off list, applied to all prices below.
Size
Estado
Price
Qty
1mg
G288045-1mg
8-12 wks(?) Production requires sourcing of materials. We appreciate your patience and understanding.
58,90US$
5mg
G288045-5mg
3

209,90US$

314,90US$
Guardar 105,00 US$ (33.34%)
10mg
G288045-10mg
2

254,90US$

382,90US$
Guardar 128,00 US$ (33.43%)
25mg
G288045-25mg
2

358,90US$

538,90US$
Guardar 180,00 US$ (33.40%)
50mg
G288045-50mg
2

538,90US$

808,90US$
Guardar 270,00 US$ (33.38%)
100mg
G288045-100mg
2

808,90US$

1.213,90US$
Guardar 405,00 US$ (33.36%)
Enter a quantity for the sizes you want to add.
Bulk / Custom
♡ Lista de deseos ⇅ Añadir para comparar ⎙ Print page
SDS
Safety data
COA
Certificate
DS
Datasheet
SP
Spec sheet
Specifications Nombres e identificadores Documentation Advanced Data Taxonomic Classification Estructura 3D Objetivos asociados (humanos) Mecanismos de acción Certificados (CoA, COO, BSE/TSE y tabla de análisis) Propiedades químicas y físicas Calculadoras de soluciones Reseñas
🧪

Why this grade

≥98%(HPLC) for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Store at -20°C,Argon charged Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Specifications

Sinónimos
N-(2, 3-Dihydro-1, 4-benzodioxin-6-yl)-1, 4-dihydroindeno[1, 2-c]pyrazol-3-amine | GN44028
Especificaciones y pureza
≥98%(HPLC)
Mecanismos bioquímicos y fisiológicos
Potent HIF-1αinhibitor (IC50= 14 nM). Inhibits hypoxia-induced HIF-1αtranscriptional activity without suppressing HIF-1αmRNA expression, HIF-1αprotein accumulation, or HIF-1α/HIF-1βheterodimerization. Cytotoxic to a range of cancer cell typesin vitro.
Condiciones de almacenamiento de almacenamiento
Store at -20°C, Argon charged
Enviado en
Ice chest + Ice pads
Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.
Tipo de acción
INHIBITOR
Pureza
≥98%(HPLC)
Nombres e identificadores
Pubchem Sid504772186
Pubchem Sid Urlhttps://pubchem.ncbi.nlm.nih.gov/substance/504772186
Sonrisas canónicasC1COC2=C(O1)C=CC(=C2)NC3=NNC4=C3CC5=CC=CC=C54
IUPAC NameN-(2,3-dihydro-1,4-benzodioxin-6-yl)-1,4-dihydroindeno[1,2-c]pyrazol-3-amine
InChIKeyCGZKSZVSWAAUHE-UHFFFAOYSA-N
INCHI1S/C18H15N3O2/c1-2-4-13-11(3-1)9-14-17(13)20-21-18(14)19-12-5-6-15-16(10-12)23-8-7-22-15/h1-6,10H,7-9H2,(H2,19,20,21)
Isómeros SMILES C1COC2=C(O1)C=CC(=C2)NC3=NNC4=C3CC5=CC=CC=C54
Peso molecular 305.33
Reaxy-Rn 23401922
Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=23401922&ln=

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Taxonomic Classification

Taxonomy Tree

KingdomOrganic compounds
SuperclassOrganoheterocyclic compounds
ClaseBenzodioxanes
SubclassBenzo-1,4-dioxanes
Intermediate Tree Nodes Not available
Direct ParentBenzo-1,4-dioxanes
Alternative Parents Alkyl aryl ethers  Para dioxins  Imidolactams  Benzenoids  Pyrazoles  Heteroaromatic compounds  Oxacyclic compounds  Azacyclic compounds  Hydrocarbon derivatives  Amines  
Molecular FrameworkAromatic heteropolycyclic compounds
Substituents Benzo-1,4-dioxane - Alkyl aryl ether - Para-dioxin - Benzenoid - Imidolactam - Azole - Pyrazole - Heteroaromatic compound - Ether - Oxacycle - Azacycle - Amine - Hydrocarbon derivative - Organooxygen compound - Organonitrogen compound - Organic oxygen compound - Organic nitrogen compound - Aromatic heteropolycyclic compound
DescripciónThis compound belongs to the class of organic compounds known as benzo-1,4-dioxanes. These are heterocyclic compounds containing a benzene ring fused to a 1,4-dioxane ring.
External Descriptors Not available
Estructura 3D
Modelo de Estructura Química Interactiva





Objetivos asociados (humanos)
HIF1A Tchem Hypoxia-inducible factor 1-alpha (1 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
PC-3 (62116 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HCT-116 (91556 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HepG2 (196354 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HeLa (62764 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HIF1A Tchem Hypoxia-inducible factor 1 alpha (6027 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mecanismos de acción
Certificados (CoA, COO, BSE/TSE y tabla de análisis)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

6 results found

Lot NumberCertificate TypeFechaArticulo
B2602068Certificate of AnalysisFeb 25, 2026 G288045
K2218453Certificate of AnalysisSep 04, 2025 G288045
K2218454Certificate of AnalysisSep 04, 2025 G288045
K2218455Certificate of AnalysisSep 04, 2025 G288045
K2218456Certificate of AnalysisSep 04, 2025 G288045
K2218469Certificate of AnalysisSep 04, 2025 G288045
Propiedades químicas y físicas
SolubilidadSolvent:DMSO, Max Conc. mg/mL: 30.53, Max Conc. mM: 100; Solvent:ethanol, Max Conc. mg/mL: 30.53, Max Conc. mM: 100
Peso molecular305.300 g/mol
XLogP33.500
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count4
Rotatable Bond Count2
Exact Mass305.116 Da
Monoisotopic Mass305.116 Da
Topological Polar Surface Area59.200 Ų
Heavy Atom Count23
Formal Charge0
Complexity434.000
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
The total count of all stereochemical bonds0
Covalently-Bonded Unit Count1
Calculadoras de soluciones
Reseñas

Reseñas de cliente

We use cookies to ensure the website functions properly and, where permitted, to improve your experience. You can manage your preferences at any time in Settings. Learn more in our Cookie Policy.

Shall we send you a message when we have discounts available?

Remind me later

Thank you! Please check your email inbox to confirm.

Oops! Notifications are disabled.

Privacy Policy Terms of Use Cookie Policy Terms and Conditions of Sale Sales Policy
Products are supplied to verified businesses, institutions, and qualified professionals for research and development use only. Not for use in humans, animals, diagnosis, or therapy.
Copyright © 2023–present Aladdin Scientific Corp. All rights reserved.