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· · COA & SDS Disponible para cada producto · Same-day shipping on in-stock items GNE-617 - 10mM in DMSO , CAS No.1362154-70-8
GRADE & PURITY 10mM in DMSO
Synonyms
Imidazo[1,2-a]pyridine-6-carboxamide,N-[[4-[(3,5-difluorophenyl)sulfonyl]phenyl]methyl]-
Shipped In
Dry ice packs + Cold packs
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Why this grade 10mM in DMSO for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
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Storage & shipping Store at -80°C Ships Dry ice packs + Cold packs Check lot-specific COA for exact specifications.
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Quality documents SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
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Literature proof Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Descripción general Information
GNE-617 GNE-617 is a highly potent inhibitor of NAMPT activity with an IC50 of 5 nM.
Targets
NAMPT (Cell-free assay) 5 nM
Specifications Sinónimos
Imidazo[1, 2-a]pyridine-6-carboxamide, N-[[4-[(3, 5-difluorophenyl)sulfonyl]phenyl]methyl]-
Especificaciones y pureza
10mM in DMSO
Mecanismos bioquímicos y fisiológicos
GNE-617 is a highly potent inhibitor of NAMPT activity with an IC50 of 5 nM.
Condiciones de almacenamiento de almacenamiento
Store at -80°C
Enviado en
Dry ice packs + Cold packs
Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.
Propiedades del producto ALogP 2.875 hba_count 4 Recuento HBD 1 Enlace rotable 5
Nombres e identificadores Sonrisas canónicas C1=CC(=CC=C1CNC(=O)C2=CN3C=CN=C3C=C2)S(=O)(=O)C4=CC(=CC(=C4)F)F IUPAC Name N-[[4-(3,5-difluorophenyl)sulfonylphenyl]methyl]imidazo[1,2-a]pyridine-6-carboxamide InChIKey XRDVXQQZLHVEQZ-UHFFFAOYSA-N INCHI 1S/C21H15F2N3O3S/c22-16-9-17(23)11-19(10-16)30(28,29)18-4-1-14(2-5-18)12-25-21(27)15-3-6-20-24-7-8-26(20)13-15/h1-11,13H,12H2,(H,25,27) Isómeros SMILES C1=CC(=CC=C1CNC(=O)C2=CN3C=CN=C3C=C2)S(=O)(=O)C4=CC(=CC(=C4)F)F Peso molecular 427.42 Reaxy-Rn 22322434 Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=22322434&ln=
Documentation 📋 Safety Data Sheet (SDS) Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS → ✅ Certificate of Analysis (COA) Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA → 📊 Datasheet Quick-reference summary of product specifications and applications.
View datasheet → 🔬 Specification Sheet Full quality attributes and acceptance criteria for this grade.
View spec sheet →
Advanced Data Taxonomic Classification Kingdom Organic compounds Superclass Organoheterocyclic compounds Clase Imidazopyridines Subclass Not available Intermediate Tree Nodes Not available Direct Parent Imidazopyridines Alternative Parents Benzenesulfonyl compounds Pyridinecarboxamides Imidazo[1,2-a]pyridines Fluorobenzenes Aryl fluorides N-substituted imidazoles Vinylogous amides Sulfones Heteroaromatic compounds Secondary carboxylic acid amides Azacyclic compounds Organooxygen compounds Hydrocarbon derivatives Organonitrogen compounds Organic oxides Organofluorides Molecular Framework Aromatic heteropolycyclic compounds Substituents Imidazo[1,2-a]pyridine - Benzenesulfonyl group - Imidazopyridine - Pyridinecarboxamide - Pyridine carboxylic acid or derivatives - Fluorobenzene - Halobenzene - Aryl fluoride - Aryl halide - Monocyclic benzene moiety - N-substituted imidazole - Benzenoid - Pyridine - Azole - Heteroaromatic compound - Imidazole - Vinylogous amide - Sulfonyl - Sulfone - Carboxamide group - Secondary carboxylic acid amide - Azacycle - Carboxylic acid derivative - Organofluoride - Organohalogen compound - Organic oxygen compound - Organic nitrogen compound - Hydrocarbon derivative - Organonitrogen compound - Organooxygen compound - Organosulfur compound - Organic oxide - Aromatic heteropolycyclic compound Descripción This compound belongs to the class of organic compounds known as imidazopyridines. These are organic polycyclic compounds containing an imidazole ring fused to a pyridine ring. Imidazole is 5-membered ring consisting of three carbon atoms, and two nitrogen centers at the 1- and 3-positions. Pyridine is a 6-membered ring consisting of five carbon atoms and one nitrogen center. External Descriptors Not available Data sources 1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.
Estructura 3D Objetivos asociados (humanos) Objetivos asociados (no humanos) Mecanismos de acción Certificados (CoA, COO, BSE/TSE y tabla de análisis) Propiedades químicas y físicas DMSO (mg/ml) Solubilidad máxima 42 DMSO (mM) Solubilidad máxima 98.2640026203734 Agua (mg/ml) Solubilidad máxima ＜1 Peso molecular 427.400 g/mol XLogP3 3.500 Hydrogen Bond Donor Count 1 Hydrogen Bond Acceptor Count 6 Rotatable Bond Count 5 Exact Mass 427.08 Da Monoisotopic Mass 427.08 Da Topological Polar Surface Area 88.900 Ų Heavy Atom Count 30 Formal Charge 0 Complexity 699.000 Isotope Atom Count 0 Defined Atom Stereocenter Count 0 Undefined Atom Stereocenter Count 0 Defined Bond Stereocenter Count 0 Undefined Bond Stereocenter Count 0 The total count of all stereochemical bonds 0 Covalently-Bonded Unit Count 1
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