Goralatide - Moligand™, ≥90% , CAS No.120081-14-3

CAS: 120081-14-3 Cat. No.: G276013 Peso molecular: 487.51

GRADE & PURITY Moligand™, ≥90%

Synonyms

acetyl-N-Ser-Asp-Lys-Pro | acetyl-seryl-aspartyl-lysyl-prolinamide | CAS-120081-14-3 | GTPL10060 | acetyl-SDKP | AcSDKP | Ac-SDKP | DTXSID0057629 | L-PROLINE, N-ACETYL-L-SERYL-L-.ALPHA.-ASPARTYL-L-LYSYL- | Acetyl-serinyl-aspartyl-lysinyl-proline | H041538

Storage

Store at -20°C,Desiccated

Shipped In

Ice chest + Ice pads

Descripción general

Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.

Specifications

Sinónimos

acetyl-N-Ser-Asp-Lys-Pro | acetyl-seryl-aspartyl-lysyl-prolinamide | CAS-120081-14-3 | GTPL10060 | acetyl-SDKP | AcSDKP | Ac-SDKP | DTXSID0057629 | L-PROLINE, N-ACETYL-L-SERYL-L-.ALPHA.-ASPARTYL-L-LYSYL- | Acetyl-serinyl-aspartyl-lysinyl-proline | H041538

Especificaciones y pureza

Moligand™, ≥90%

Mecanismos bioquímicos y fisiológicos

Hematopoietic progenitor cell cycle inhibitor. Protects against chemotherapy in normal hematopoietic cells. In vivo .

Condiciones de almacenamiento de almacenamiento

Store at -20°C, Desiccated

Enviado en

Ice chest + Ice pads

Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.

Grado

Moligand™

Tipo de acción

ACTIVATOR

Nota

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one week. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

Pureza

≥90%

Nombres e identificadores

• Sonrisas canónicas: CC(=O)NC(CO)C(=O)NC(CC(=O)O)C(=O)NC(CCCCN)C(=O)N1CCCC1C(=O)O
• IUPAC Name: (2S)-1-[(2S)-2-[[(2S)-2-[[(2S)-2-acetamido-3-hydroxypropanoyl]amino]-3-carboxypropanoyl]amino]-6-aminohexanoyl]pyrrolidine-2-carboxylic acid
• InChIKey: HJDRXEQUFWLOGJ-AJNGGQMLSA-N
• INCHI: 1S/C20H33N5O9/c1-11(27)22-14(10-26)18(31)24-13(9-16(28)29)17(30)23-12(5-2-3-7-21)19(32)25-8-4-6-15(25)20(33)34/h12-15,26H,2-10,21H2,1H3,(H,22,27)(H,23,30)(H,24,31)(H,28,29)(H,33,34)/t12-,13-,14-,15-/m0/s1
• Isómeros SMILES: CC(=O)N[C@@H](CO)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)O
• Peso molecular: 487.51
• Reaxy-Rn: 43404560
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=43404560&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organic acids and derivatives
    • Clase Carboxylic acids and derivatives
      • Subclass Amino acids, peptides, and analogues
        • Level5 Peptides
          • Level6 Oligopeptides

• Kingdom: Organic compounds
• Superclass: Organic acids and derivatives
• Clase: Carboxylic acids and derivatives
• Subclass: Amino acids, peptides, and analogues
• Intermediate Tree Nodes: Peptides
• Direct Parent: Oligopeptides
• Alternative Parents: Aspartic acid and derivatives N-acyl-L-alpha-amino acids Proline and derivatives Serine and derivatives Alpha amino acid amides N-acylpyrrolidines Pyrrolidine carboxylic acids Hydroxy fatty acids Heterocyclic fatty acids N-acyl amines Dicarboxylic acids and derivatives Tertiary carboxylic acid amides Acetamides Amino acids Secondary carboxylic acid amides Carboxylic acids Azacyclic compounds Carbonyl compounds Hydrocarbon derivatives Monoalkylamines Organic oxides Organopnictogen compounds Primary alcohols
• Molecular Framework: Aliphatic heteromonocyclic compounds
• Substituents: Alpha-oligopeptide - Aspartic acid or derivatives - Proline or derivatives - N-acyl-alpha-amino acid - N-acyl-l-alpha-amino acid - N-acyl-alpha amino acid or derivatives - Alpha-amino acid amide - Serine or derivatives - N-substituted-alpha-amino acid - Alpha-amino acid or derivatives - N-acylpyrrolidine - Pyrrolidine carboxylic acid - Pyrrolidine carboxylic acid or derivatives - Heterocyclic fatty acid - Hydroxy fatty acid - Dicarboxylic acid or derivatives - Fatty amide - N-acyl-amine - Fatty acyl - Fatty acid - Tertiary carboxylic acid amide - Pyrrolidine - Acetamide - Secondary carboxylic acid amide - Amino acid or derivatives - Carboxamide group - Amino acid - Azacycle - Organoheterocyclic compound - Carboxylic acid - Organooxygen compound - Primary amine - Organic oxide - Alcohol - Primary aliphatic amine - Organic nitrogen compound - Carbonyl group - Organic oxygen compound - Amine - Organopnictogen compound - Hydrocarbon derivative - Primary alcohol - Organonitrogen compound - Aliphatic heteromonocyclic compound
• Descripción: This compound belongs to the class of organic compounds known as oligopeptides. These are organic compounds containing a sequence of between three and ten alpha-amino acids joined by peptide bonds.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Objetivos asociados (humanos)

ACE Tclin Angiotensin-converting enzyme (1423 Activities)

Discover Target: ACE

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

HL-60 (67320 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

HEL (6614 Activities)

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Jurkat (10389 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mecanismos de acción

Propiedades químicas y físicas

• Solubilidad: Soluble in water
• Peso molecular: 487.500 g/mol
• XLogP3: -5.400
• Hydrogen Bond Donor Count: 7
• Hydrogen Bond Acceptor Count: 10
• Rotatable Bond Count: 14
• Exact Mass: 487.228 Da
• Monoisotopic Mass: 487.228 Da
• Topological Polar Surface Area: 228.000 Ų
• Heavy Atom Count: 34
• Formal Charge: 0
• Complexity: 776.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 4
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1