GSK 1562590 hydrochloride - ≥98%(HPLC) , CAS No.1003878-07-6

CAS: 1003878-07-6 Cat. No.: G287869 Peso molecular: 617.95 PubChem CID: 46909864

GRADE & PURITY ≥98%(HPLC)

Synonyms

N-[(1R)-1-[3'-(Aminocarbonyl)[1,1'-biphenyl]-4-yl]-2-(1-pyrrolidinyl)ethyl]-6,7-dichloro-2,3-dihydro-N-methyl-3-oxo-4H-1,4-benzoxazine-4-acetamide hydrochloride

Storage

Store at 2-8°C

Shipped In

Wet ice

Specifications

Sinónimos

N-[(1R)-1-[3'-(Aminocarbonyl)[1, 1'-biphenyl]-4-yl]-2-(1-pyrrolidinyl)ethyl]-6, 7-dichloro-2, 3-dihydro-N-methyl-3-oxo-4H-1, 4-benzoxazine-4-acetamide hydrochloride

Especificaciones y pureza

≥98%(HPLC)

Mecanismos bioquímicos y fisiológicos

High affinity and selective urotensin II (UT) receptor antagonist (pKivalues are 9.14, 9.28, 9.34, 9.64 and 9.66 at monkey, human, mouse, cat and rat recombinant receptors respectively). Exhibits selectivity for UT receptors over a range of GPCRs, ion cha

Condiciones de almacenamiento de almacenamiento

Store at 2-8°C

Enviado en

Wet ice

Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.

Tipo de acción

ANTAGONIST

Pureza

≥98%(HPLC)

Nombres e identificadores

• Sonrisas canónicas: CN(C(CN1CCCC1)C2=CC=C(C=C2)C3=CC(=CC=C3)C(=O)N)C(=O)CN4C(=O)COC5=CC(=C(C=C54)Cl)Cl.Cl
• IUPAC Name: 3-[4-[(1R)-1-[[2-(6,7-dichloro-3-oxo-1,4-benzoxazin-4-yl)acetyl]-methylamino]-2-pyrrolidin-1-ylethyl]phenyl]benzamide;hydrochloride
• InChIKey: XTVXEMMIPYMBLL-SNYZSRNZSA-N
• INCHI: 1S/C30H30Cl2N4O4.ClH/c1-34(28(37)17-36-25-14-23(31)24(32)15-27(25)40-18-29(36)38)26(16-35-11-2-3-12-35)20-9-7-19(8-10-20)21-5-4-6-22(13-21)30(33)39;/h4-10,13-15,26H,2-3,11-12,16-18H2,1H3,(H2,33,39);1H/t26-;/m0./s1
• Isómeros SMILES: CN([C@@H](CN1CCCC1)C2=CC=C(C=C2)C3=CC(=CC=C3)C(=O)N)C(=O)CN4C(=O)COC5=CC(=C(C=C54)Cl)Cl.Cl
• PubChem CID: 46909864
• Peso molecular: 617.95

Propiedades químicas y físicas

• Solubilidad: Solvent:DMSO, Max Conc. mg/mL: 61.8, Max Conc. mM: 100