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GSK2983559 - ≥99% , CAS No.G658853
Disponible para pedir
GRADE & PURITY ≥99%
Storage
Store at -20°C,Desiccated
Shipped In
Ice chest + Ice pads
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Why this grade
≥99% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Storage & shipping
Store at -20°C,Desiccated Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.
Quality documents
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Literature proof
Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Descripción general
GSK2983559 is an orally active and potent receptor interacting protein 2 ( RIP2 ) kinase inhibitor. GSK2983559 blocks many proinflammatory cytokine responses in vivo and in human inflammatory bowel disease explant samples.
Appearance:Solid
IC50& Target:RIPK2
In Vitro:GSK2983559 (1-1024 nM; 2 h) blocks MDP-induced IL-8 in THP-1 cells. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Cell Viability AssayCell Line: THP-1 cells Concentration: 1-1024 nM Incubation Ti
In Vivo:GSK2983559 (oral gavage; 3 and 10mg/kg; once) inhibits effectively MDP-induced IL-6 in mouse. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Animal Model: C57BL/6 mice (female) injected with MDP (100
Biological Activity:GSK2983559 is an orally active and potent receptor interacting protein 2 ( RIP2 ) kinase inhibitor. GSK2983559 blocks many proinflammatory cytokine responses in vivo and in human inflammatory bowel disease explant samples.
Specifications
Especificaciones y pureza
≥99%
Condiciones de almacenamiento de almacenamiento
Store at -20°C, Desiccated
Enviado en
Ice chest + Ice pads
Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.
Tipo de acción
INHIBITOR
Pureza
≥99%
Nombres e identificadores
| Peso molecular | 611.61 |
|---|
Documentation
📋 Safety Data Sheet (SDS)
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →✅ Certificate of Analysis (COA)
Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →🔬 Specification Sheet
Full quality attributes and acceptance criteria for this grade.
View spec sheet →Advanced Data
Certificados (CoA, COO, BSE/TSE y tabla de análisis)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:
Propiedades químicas y físicas
| Solubilidad | H2O : 2 mg/mL (3.27 mM; Need ultrasonic) DMSO : ＜ 1 mg/mL (ultrasonic;warming;heat to 80°C) (insoluble or slightly soluble) DMF : ＜ 1 mg/mL (ultrasonic;warming;heat to 80°C) (insoluble) Ethanol : ＜ 1 mg/mL (ultrasonic) (insoluble) G |
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