This compound belongs to the class of organic compounds known as guaianes. These are sesquiterpenoids with a structure based on the guaiane skeleton. Guaiane is a bicyclic compound consisting of a decahydroazulene moiety, substituted with two methyl groups and a 1-methylethyl group at the 1-, 4-, and 7-position, respectively.
External Descriptors
Guaiane sesquiterpenoids
1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.
1.Chen Pohua, Liu Yang, Zhang Chaochao, Huang Fei, Liu Leifeng, Sun Junliang. (2022) Crystalline Sponge Method by Three-Dimensional Electron Diffraction. Frontiers in Molecular Biosciences, [PMID:35198600][10.3389/fmolb.2021.821927]
2.Ye Qin, Zhou Li, Jin Ping, Li Lei, Zheng Shuwen, Huang Zhao, Liu Jiayang, Qin Siyuan, Liu Hao, Zou Bingwen, Xie Ke. (2021) Guaiazulene Triggers ROS-Induced Apoptosis and Protective Autophagy in Non-small Cell Lung Cancer. Frontiers in Pharmacology, [PMID:33935713][10.3389/fphar.2021.621181]
3.Yan Yang, Siying Liu, Yan Wang, Qin Yang, Baoan Wang, Yuting Zhang, Zaikang Tong, Junhong Zhang. (2025) Antifungal mechanisms of Phoebe bournei wood essential oil against Botryosphaeria dothidea and its application in apples. POSTHARVEST BIOLOGY AND TECHNOLOGY, [PMID:][10.1016/j.postharvbio.2025.113703]
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