Determine the necessary mass, volume, or concentration for preparing a solution.
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Moligand™, ≥97% Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Store at 2-8°C Ships Wet ice Check lot-specific COA for exact specifications.
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Cited in 15 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
GW9662 is a selective PPAR antagonist for PPARγ with IC50 of 3.3 nM, with at least 100 to 1000-fold functional selectivity in cells with PPARγ versus PPARα and PPARδ.
A selective, irreversible, and effective PPARγ antagonist that also acts as a FXR and PXR agonist.
| Pubchem Sid | 504759763 |
|---|---|
| Pubchem Sid Url | https://pubchem.ncbi.nlm.nih.gov/substance/504759763 |
| Sonrisas canónicas | C1=CC=C(C=C1)NC(=O)C2=C(C=CC(=C2)[N+](=O)[O-])Cl |
| IUPAC Name | 2-chloro-5-nitro-N-phenylbenzamide |
| InChIKey | DNTSIBUQMRRYIU-UHFFFAOYSA-N |
| INCHI | 1S/C13H9ClN2O3/c14-12-7-6-10(16(18)19)8-11(12)13(17)15-9-4-2-1-3-5-9/h1-8H,(H,15,17) |
| Isómeros SMILES | C1=CC=C(C=C1)NC(=O)C2=C(C=CC(=C2)[N+](=O)[O-])Cl |
| WGK Alemania | 3 |
| Peso molecular | 276.68 |
| Reaxy-Rn | 2749539 |
| Reaxys-RN_link_address | https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=2749539&ln= |
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →Full quality attributes and acceptance criteria for this grade.
View spec sheet →Taxonomy Tree
| Kingdom | Organic compounds |
|---|---|
| Superclass | Benzenoids |
| Clase | Benzene and substituted derivatives |
| Subclass | Nitrobenzenes |
| Intermediate Tree Nodes | Not available |
| Direct Parent | Nitrobenzenes |
| Alternative Parents | Nitroaromatic compounds Chlorobenzenes Aryl chlorides Propargyl-type 1,3-dipolar organic compounds Organic oxoazanium compounds Carboximidic acids Organopnictogen compounds Organooxygen compounds Organonitrogen compounds Organochlorides Organic zwitterions Organic oxides Hydrocarbon derivatives |
| Molecular Framework | Aromatic homomonocyclic compounds |
| Substituents | Nitrobenzene - Nitroaromatic compound - Chlorobenzene - Halobenzene - Aryl chloride - Aryl halide - C-nitro compound - Organic nitro compound - Propargyl-type 1,3-dipolar organic compound - Allyl-type 1,3-dipolar organic compound - Organic 1,3-dipolar compound - Carboximidic acid - Carboximidic acid derivative - Organic oxoazanium - Organic nitrogen compound - Organochloride - Organohalogen compound - Hydrocarbon derivative - Organic oxide - Organopnictogen compound - Organonitrogen compound - Organooxygen compound - Organic oxygen compound - Organic zwitterion - Aromatic homomonocyclic compound |
| Descripción | This compound belongs to the class of organic compounds known as nitrobenzenes. These are compounds containing a nitrobenzene moiety, which consists of a benzene ring with a carbon bearing a nitro group. |
| External Descriptors | benzamides |
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Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Fecha | Articulo |
|---|---|---|---|
| Certificate of Analysis | Jan 20, 2026 | G283876 | |
| Certificate of Analysis | Jan 20, 2026 | G283876 | |
| Certificate of Analysis | Jan 20, 2026 | G283876 | |
| Certificate of Analysis | Dec 16, 2025 | G283876 | |
| Certificate of Analysis | Dec 16, 2025 | G283876 | |
| Certificate of Analysis | Mar 11, 2024 | G283876 |
| Solubilidad | Soluble in DMSO (26 mg/ml), methanol, 100% ethanol (10 mg/ml), DMF (~35 mg/ml), and 1:2 DMF : PBS (PH=7.2) (~0.5 mg/ml). Insoluble in water. |
|---|---|
| Peso molecular | 276.670 g/mol |
| XLogP3 | 3.300 |
| Hydrogen Bond Donor Count | 1 |
| Hydrogen Bond Acceptor Count | 3 |
| Rotatable Bond Count | 2 |
| Exact Mass | 276.03 Da |
| Monoisotopic Mass | 276.03 Da |
| Topological Polar Surface Area | 74.900 Ų |
| Heavy Atom Count | 19 |
| Formal Charge | 0 |
| Complexity | 339.000 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| The total count of all stereochemical bonds | 0 |
| Covalently-Bonded Unit Count | 1 |
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| 3. Yushuang Liu, Hanshu Zhao, Nan Chen, Yuelong Li, Zeyang Zheng, Zhiyu Sun, Zhongling Zhang. (2023) PHLDA1 knockdown alleviates mitochondrial dysfunction and endoplasmic reticulum stress-induced neuronal apoptosis via activating PPARγ in cerebral ischemia-reperfusion injury. BRAIN RESEARCH BULLETIN, [PMID:36681251] [10.1016/j.brainresbull.2023.01.007] |
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| 6. Zhishen Xie, Jianping Zhao, Hui Wang, Yali Jiang, Qiaoling Yang, Yu Fu, Huahui Zeng, Christian Hölscher, Jiangyan Xu, Zhenqiang Zhang. (2020) Magnolol alleviates Alzheimer's disease-like pathology in transgenic C. elegans by promoting microglia phagocytosis and the degradation of beta-amyloid through activation of PPAR-γ. BIOMEDICINE & PHARMACOTHERAPY, [PMID:32000045] [10.1016/j.biopha.2020.109886] |
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| 9. Wei Guo, Jian Han, Shengmin Wu, Xiongjie Shi, Qiangwei Wang, Bingsheng Zhou. (2019) Bis(2-ethylhexyl)-2,3,4,5-tetrabromophthalate Affects Lipid Metabolism in Zebrafish Larvae via DNA Methylation Modification. ENVIRONMENTAL SCIENCE & TECHNOLOGY, [PMID:31804803] [10.1021/acs.est.9b05796] |
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View Moligand™ grade guide →