[³H]LTD₄ - Moligand™ , Agonist of CysLT 1 receptor;Agonist of CysLT 2 receptor, CAS No.H614158, Agonist of CysLT 1 receptor;Agonist of CysLT 2 receptor

CAS: H614158 Cat. No.: H614158 PubChem CID: 6435286

GRADE & PURITY Moligand™

Synonyms

[3H]LTD4 | [3H]-LTD4 | BML1-E08 | (5S,6R,7E,9E,11Z,14Z)-6-({2-amino-2-[(carboxymethyl)carbamoyl]ethyl}sulfanyl)-5-hydroxyicosa-7,9,11,14-tetraenoic acid | SCHEMBL4295683 | GTPL3353 | GTPL3412 | DTXSID6040533 | LTD4 | NCGC00161277-01 | YEESKJGWJFYOOK-LDDGI

Storage

Room temperature

Specifications

Sinónimos

[3H]LTD4 | [3H]-LTD4 | BML1-E08 | (5S, 6R, 7E, 9E, 11Z, 14Z)-6-({2-amino-2-[(carboxymethyl)carbamoyl]ethyl}sulfanyl)-5-hydroxyicosa-7, 9, 11, 14-tetraenoic acid | SCHEMBL4295683 | GTPL3353 | GTPL3412 | DTXSID6040533 | LTD4 | NCGC00161277-01 | YEESKJGWJFYOOK-LDDGI

Especificaciones y pureza

Moligand™

Condiciones de almacenamiento de almacenamiento

Room temperature

Grado

Moligand™

Tipo de acción

AGONIST

Mecanismo de acción

Agonist of CysLT 1 receptor;Agonist of CysLT 2 receptor

Nombres e identificadores

• Sonrisas canónicas: CCCCC/C=C\C/C=C\C=C\C=C\[C@H]([C@H](CCCC(=O)O)O)SCC(C(=O)NCC(=O)O)N
• IUPAC Name: (5S,6R,7E,9E,11Z,14Z)-6-({2-amino-2-[(carboxymethyl)carbamoyl]ethyl}sulfanyl)-5-hydroxyicosa-7,9,11,14-tetraenoic acid
• InChIKey: YEESKJGWJFYOOK-LDDGIIIKSA-N
• INCHI: 1S/C25H40N2O6S/c1-2-3-4-5-6-7-8-9-10-11-12-13-16-22(21(28)15-14-17-23(29)30)34-19-20(26)25(33)27-18-24(31)32/h6-7,9-13,16,20-22,28H,2-5,8,14-15,17-19,26H2,1H3,(H,27,33)(H,29,30)(H,31,32)/b7-6-,10-9-,12-11+,16-13+/t20?,21-,22+/m0/s1
• Isómeros SMILES: CCCCC/C=C\C/C=C\C=C\C=C\[C@H]([C@H](CCCC(=O)O)O)SCC(C(=O)NCC(=O)O)N
• PubChem CID: 6435286

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Lipids and lipid-like molecules
    • Clase Fatty Acyls
      • Subclass Eicosanoids

• Kingdom: Organic compounds
• Superclass: Lipids and lipid-like molecules
• Clase: Fatty Acyls
• Subclass: Eicosanoids
• Intermediate Tree Nodes: Not available
• Direct Parent: Leukotrienes
• Alternative Parents: Hydroxyeicosatetraenoic acids Dipeptides Long-chain fatty acids N-acyl-alpha amino acids Alpha amino acid amides Cysteine and derivatives Thia fatty acids Hydroxy fatty acids Unsaturated fatty acids Dicarboxylic acids and derivatives Secondary carboxylic acid amides Secondary alcohols Amino acids Sulfenyl compounds Carboxylic acids Dialkylthioethers Organic oxides Organopnictogen compounds Carbonyl compounds Monoalkylamines Hydrocarbon derivatives
• Molecular Framework: Aliphatic acyclic compounds
• Substituents: Leukotriene - Hydroxyeicosatetraenoic acid - Alpha-dipeptide - Alpha peptide - Long-chain fatty acid - N-acyl-alpha amino acid or derivatives - N-acyl-alpha-amino acid - Alpha-amino acid amide - Cysteine or derivatives - Alpha-amino acid or derivatives - Hydroxy fatty acid - Thia fatty acid - Dicarboxylic acid or derivatives - Fatty acid - Unsaturated fatty acid - Secondary alcohol - Secondary carboxylic acid amide - Amino acid - Carboxamide group - Amino acid or derivatives - Carboxylic acid derivative - Carboxylic acid - Dialkylthioether - Sulfenyl compound - Thioether - Amine - Organic oxygen compound - Organic nitrogen compound - Hydrocarbon derivative - Alcohol - Organic oxide - Carbonyl group - Organopnictogen compound - Primary amine - Primary aliphatic amine - Organosulfur compound - Organooxygen compound - Organonitrogen compound - Aliphatic acyclic compound
• Descripción: This compound belongs to the class of organic compounds known as leukotrienes. These are eicosanoids containing a hydroxyl group attached to the aliphatic chain of an arachidonic acid. Leukotrienes have four double bonds, three (and only three) of which are conjugated.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Objetivos asociados (humanos)

GPR17 Tchem Uracil nucleotide/cysteinyl leukotriene receptor (0 Activities)

Discover Target: GPR17

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

CYSLTR2 Tchem Cysteinyl leukotriene receptor 2 (0 Activities)

Discover Target: CYSLTR2

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

CYSLTR1 Tclin Cysteinyl leukotriene receptor 1 (1 Activities)

Discover Target: CYSLTR1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

APEX1 Tchem DNA-(apurinic or apyrimidinic site) lyase (38016 Activities)

Discover Target: APEX1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mecanismos de acción