Haloperidol - Moligand™, 10mM in DMSO , Antagonist of 5-HT 1A receptor;Antagonist of 5-HT 1D receptor;Antagonist of 5-HT 2A receptor;Antagonist of 5-HT 2B receptor;Antagonist of 5-HT 7 receptor;Antagonist of D 1 receptor;Antagonist of D 2 receptor;Antagon, Antagonist of 5-HT 1A receptor;Antagonist of 5-HT 1D receptor;Antagonist of 5-HT 2A receptor;Antagonist of 5-HT 2B receptor;Antagonist of 5-HT 7 receptor;Antagonist of D 1 receptor;Antagonist of D 2 receptor;Antagonist of D 3 receptor;Antagonist of D 4 re

CAS: 52-86-8 Cat. No.: H408755 Peso molecular: 375.86 Beilstein Registry Number: 21(5)2,377 Número EC: 200-155-6
Disponible para pedir
GRADE & PURITY Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10mM in DMSO
Synonyms
4-​[4-​(4-​chlorophenyl)​-​4-​hydroxy-​1-​piperidinyl]​-​1-​(4-​fluorophenyl)​-1-​butanone
Storage
Store at -80°C
Shipped In
Dry ice packs + Cold packs
 ·  off list, applied to all prices below.
Size
Estado
Price
Qty
1ml
H408755-1ml
2

93,90US$

135,90US$
Guardar 42,00 US$ (30.91%)
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Why this grade

Moligand™, 10mM in DMSO Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

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Storage & shipping

Store at -80°C Ships Dry ice packs + Cold packs Check lot-specific COA for exact specifications.

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Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 11 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Descripción general

Information

Haloperidol Haloperidol (Haldol) is an antipsychotic and butyrophenone.
In vitro


In vivo


Cell Data

cell lines:

Concentrations:

Incubation Time:

Powder Purity:≥99%

Specifications

Sinónimos
4-​[4-​(4-​chlorophenyl)​-​4-​hydroxy-​1-​piperidinyl]​-​1-​(4-​fluorophenyl)​-1-​butanone
Especificaciones y pureza
Moligand™, 10mM in DMSO
Mecanismos bioquímicos y fisiológicos
Haloperidol (Haldol) is an antipsychotic and butyrophenone.
Condiciones de almacenamiento de almacenamiento
Store at -80°C
Enviado en
Dry ice packs + Cold packs
Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.
Grado
Moligand™
Tipo de acción
AGONIST, ANTAGONIST, CHANNEL BLOCKER, GATING INHIBITOR
Mecanismo de acción
Antagonist of 5-HT 1A receptor;Antagonist of 5-HT 1D receptor;Antagonist of 5-HT 2A receptor;Antagonist of 5-HT 2B receptor;Antagonist of 5-HT 7 receptor;Antagonist of D 1 receptor;Antagonist of D 2 receptor;Antagonist of D 3 receptor;Antagonist of D 4 re
Nombres e identificadores
Isómeros SMILES C1CN(CCC1(C2=CC=C(C=C2)Cl)O)CCCC(=O)C3=CC=C(C=C3)F
WGK Alemania 3
RTECS EU1575000
Número ONU 2811
Peso molecular 375.86
Beilstein 21(5)2,377
Reaxy-Rn 331267
Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=331267&ln=

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Objetivos asociados (humanos)
DRD1 Tclin D(1A) dopamine receptor (5 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
DRD2 Tclin D(2) dopamine receptor (106 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
DRD4 Tchem D(4) dopamine receptor (46 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
EBP Tchem 3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase (1 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
ABCB1 Tchem Multidrug resistance protein 1 (1 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
KCNJ6 Tchem G protein-activated inward rectifier potassium channel 2 (1 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
TMEM97 Tchem Sigma intracellular receptor 2 (5 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
SIGMAR1 Tclin Sigma non-opioid intracellular receptor 1 (63 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
DRD3 Tclin D(3) dopamine receptor (53 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
DRD5 Tchem D(1B) dopamine receptor (4 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
HTR2A Tclin 5-hydroxytryptamine receptor 2A (7 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
HTR7 Tclin 5-hydroxytryptamine receptor 7 (1 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
ADRA1D Tclin Alpha-1D adrenergic receptor (2 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
ADRA1A Tclin Alpha-1A adrenergic receptor (1 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
HTR1D Tclin 5-hydroxytryptamine receptor 1D (1 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
KCNK2 Tclin Potassium channel subfamily K member 2 (1 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
KCNH1 Tclin Potassium voltage-gated channel subfamily H member 1 (1 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
H1F0 Tchem Histone H1.0 (1 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
KCNH2 Tclin Potassium voltage-gated channel subfamily H member 2 (18 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
Certificados (CoA, COO, BSE/TSE y tabla de análisis)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:
Propiedades químicas y físicas
Punto de fusión (°C)148-149.4°C
Citations of This Product
Referencias
1. Huanhuan Yang, Cong Liu, Chuanhong Zhu, Yan Zheng, Juan Li, Qianyun Zhu, Hao Wang, Xiangming Fang, Quan Liu, Man Liang, Zilong Liu.  (2023)  Determination of ten antipsychotics in blood, hair and nails: Validation of a LC–MS/MS method and forensic application of keratinized matrix analysis.  JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS,      [PMID:37406464] [10.1016/j.jpba.2023.115557]
2. Linlin Chen, Xiaofei Hu, Yunrui Xing, Yaning Sun, Mei Hu, Gaiping Zhang.  (2022)  Highly sensitive immunochromatographic assay for simultaneous determination of azaperone and azaperol in pork.  Food Chemistry-X,      [PMID:36478711] [10.1016/j.fochx.2022.100525]
3. Mingqian Song, Changxin Li, Shijia Wu, Nuo Duan.  (2022)  Screening of specific aptamers against chlorpromazine and construction of novel ratiometric fluorescent aptasensor based on metal-organic framework.  TALANTA,      [PMID:36049339] [10.1016/j.talanta.2022.123850]
4. Tianyi Yang, Guang Yue, Yu Ge, Yue Zhang, Peng Xu, Youmei Wang, Bo Li, Bin Di.  (2022)  SCH 23390 inhibits the acquisition of nitrous oxide-induced conditioned place preference and the changes in ERK phosphorylation expression in nucleus accumbens of mice.  NEUROSCIENCE LETTERS,      [PMID:35525502] [10.1016/j.neulet.2022.136674]
5. Qianqian Shang, Huajing Liu, Hang Mei, Chuixiu Huang, Xiantao Shen.  (2022)  Multi-extraction system with identical supported semi-liquid membrane: Enhanced stability for coextraction of acidic and basic drugs.  TALANTA,      [PMID:35462249] [10.1016/j.talanta.2022.123485]
6. Linlin Chen, Xiaofei Hu, Yaning Sun, Yunrui Xing, Gaiping Zhang.  (2022)  An ultrasensitive monoclonal antibody-based lateral flow immunoassay for the rapid detection of xylazine in milk.  FOOD CHEMISTRY,      [PMID:35158128] [10.1016/j.foodchem.2022.132293]
7. Ruiqin Zhu, Hang Mei, Huajing Liu, Changbao Hong, Xiantao Shen, Chuixiu Huang.  (2021)  Successive liquid-phase microextraction of acidic and basic analytes.  ANALYTICA CHIMICA ACTA,      [PMID:35057942] [10.1016/j.aca.2021.339335]
8. Yujiao Yang, Junke Song, NanNan Liu, Guangyi Wei, Shan Liu, Sen Zhang, Nan Jiang, Haiguang Yang, Guanhua Du.  (2021)  Salvianolic acid A relieves cognitive disorder after chronic cerebral ischemia: Involvement of Drd2/Cryab/NF-κB pathway.  PHARMACOLOGICAL RESEARCH,      [PMID:34800628] [10.1016/j.phrs.2021.105989]
9. Libin Wan, Bin Lin, Ruiqin Zhu, Chuixiu Huang, Stig Pedersen-Bjergaard, Xiantao Shen.  (2019)  Liquid-Phase Microextraction or Electromembrane Extraction?.  ANALYTICAL CHEMISTRY,      [PMID:31141346] [10.1021/acs.analchem.9b00946]
10. Hang Mei, Huajing Liu, Qianqian Shang, Ying Dong, Stig Pedersen-Bjergaard, Chuixiu Huang, Xiantao Shen.  (2021)  Organic-solvent-free electromembrane extraction based on semi-interpenetrating polymer networks.  GREEN CHEMISTRY,  23  (4): (1782-1793).  [PMID:] [10.1039/D1GC00148E]
11. Xiao Yu, Xinlin Li, Sunzhao You, Yuhang Shi, Ruiqin Zhu, Ying Dong, Chuixiu Huang.  (2020)  Electromembrane extraction of chlorprothixene, haloperidol and risperidone from whole blood and urine.  JOURNAL OF CHROMATOGRAPHY A,      [PMID:32827905] [10.1016/j.chroma.2020.461480]
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