≥95% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Store at 2-8°C,Protected from light,Desiccated Ships Wet ice Check lot-specific COA for exact specifications.
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Cited in 2 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Product Describtion:
Hematoporphyrin monomethyl ether, second generation of porphyrin-related photosensitizer, is characterized by its single form, high yield of singlet oxygen, high selectivity, and low toxicity, which has been widely used in the diagnosis and treatment of various tumors, including lung cancer, bladder cancer, and nevus flammeus and brain glioma
Product Application:
Hematoporphyrin monomethyl ether (HMME) is a novel and promising porphyrin-related photosensitizer for photodynamic therapy (PDT). HMME-PDT can induce cell deaththrough both necrosis and apoptosis in HeLa cells. ROS, such as singlet oxygen and hydroxyl radical, generated in HeLa cells play a decisive role in HMME-PDT-induced cell death.
| Pubchem Sid | 488197595 |
|---|---|
| Pubchem Sid Url | https://pubchem.ncbi.nlm.nih.gov/substance/488197595 |
| Sonrisas canónicas | CC1=C(C2=CC3=NC(=CC4=NC(=CC5=C(C(=C(N5)C=C1N2)C(C)O)C)C(=C4CCC(=O)O)C)C(=C3C)CCC(=O)O)C(C)OC |
| IUPAC Name | 3-[18-(2-carboxyethyl)-8-(1-hydroxyethyl)-13-(1-methoxyethyl)-3,7,12,17-tetramethyl-22,23-dihydroporphyrin-2-yl]propanoic acid |
| InChIKey | NDYWLKUTUDKOAS-UHFFFAOYSA-N |
| INCHI | 1S/C35H40N4O6/c1-16-22(8-10-32(41)42)28-15-29-23(9-11-33(43)44)17(2)25(37-29)13-31-35(21(6)45-7)19(4)27(39-31)14-30-34(20(5)40)18(3)26(38-30)12-24(16)36-28/h12-15,20-21,38-40H,8-11H2,1-7H3,(H,41,42)(H,43,44) |
| Isómeros SMILES | CC1=C(C2=CC3=NC(=CC4=NC(=CC5=C(C(=C(N5)C=C1N2)C(C)O)C)C(=C4CCC(=O)O)C)C(=C3C)CCC(=O)O)C(C)OC |
| PubChem CID | 11570804 |
| Peso molecular | 612.72 |
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →Full quality attributes and acceptance criteria for this grade.
View spec sheet →Taxonomy Tree
| Kingdom | Organic compounds |
|---|---|
| Superclass | Organoheterocyclic compounds |
| Clase | Tetrapyrroles and derivatives |
| Subclass | Porphyrins |
| Intermediate Tree Nodes | Not available |
| Direct Parent | Porphyrins |
| Alternative Parents | Substituted pyrroles Dicarboxylic acids and derivatives Heteroaromatic compounds Secondary alcohols Dialkyl ethers Carboxylic acids Azacyclic compounds Organonitrogen compounds Organic oxides Hydrocarbon derivatives Carbonyl compounds Aromatic alcohols |
| Molecular Framework | Aromatic heteropolycyclic compounds |
| Substituents | Porphyrin - Dicarboxylic acid or derivatives - Substituted pyrrole - Pyrrole - Heteroaromatic compound - Secondary alcohol - Carboxylic acid derivative - Carboxylic acid - Dialkyl ether - Ether - Azacycle - Organooxygen compound - Organonitrogen compound - Alcohol - Organic nitrogen compound - Carbonyl group - Organic oxygen compound - Organic oxide - Hydrocarbon derivative - Aromatic alcohol - Aromatic heteropolycyclic compound |
| Descripción | This compound belongs to the class of organic compounds known as porphyrins. These are compounds containing a fundamental skeleton of four pyrrole nuclei united through the alpha-positions by four methine groups to form a macrocyclic structure. |
| External Descriptors | Not available |
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Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Fecha | Articulo |
|---|---|---|---|
 E2315297 | Certificate of Analysis | Feb 05, 2026 | H302937 |
| E2315302 | Certificate of Analysis | Feb 05, 2026 | H302937 |
| E2315304 | Certificate of Analysis | Feb 05, 2026 | H302937 |
| E2315306 | Certificate of Analysis | Feb 05, 2026 | H302937 |
| E2315307 | Certificate of Analysis | Feb 05, 2026 | H302937 |
| E2315309 | Certificate of Analysis | Feb 05, 2026 | H302937 |
| E2315311 | Certificate of Analysis | Feb 05, 2026 | H302937 |
| E2315308 | Certificate of Analysis | Mar 31, 2023 | H302937 |
| E2315312 | Certificate of Analysis | Mar 31, 2023 | H302937 |
| E2315315 | Certificate of Analysis | Mar 31, 2023 | H302937 |
| I2525118 | Certificate of Analysis | Mar 31, 2023 | H302937 |
| K2405024 | Certificate of Analysis | Mar 31, 2023 | H302937 |
| Solubilidad | souble in DMSO |
|---|---|
| Sensibilidad | Sensitive to light |
| Punto de ebullición (°C) | 1123.6±65.0 °C |
| 1. Ling-Kun Zhang, Shiwei Du, Xiaozhen Wang, Yuxuan Jiao, Liang Yin, Yi Zhang, Yan-Qing Guan. (2019) Bacterial cellulose based composites enhanced transdermal drug targeting for breast cancer treatment. CHEMICAL ENGINEERING JOURNAL, [PMID:] [10.1016/j.cej.2019.03.216] |
| 2. Hongxin Zhao, Fangxue Du, Jianbo Huang, Ruiqian Guo, Ziyan Feng, Ziyao Wang, Li Qiu. (2025) Biomimetic liposomal nanovesicles remodel the tumor immune microenvironment to augment sono-immunotherapy. JOURNAL OF CONTROLLED RELEASE, [PMID:40355046] [10.1016/j.jconrel.2025.113830] |
