Hexamethonium Chloride hydrate - ≥99% , CAS No.60-25-3(anhy)

CAS: 60-25-3(anhy) Cat. No.: H157034 Peso molecular: 273.29(anhy)

GRADE & PURITY ≥99%

Synonyms

Hexamethylenebis(trimethylammonium Chloride) hydrate | N,N,N,N',N',N'-Hexamethyl-1,6-hexanediammonium Dichloride hydrate | Hexane-1,6-bis(trimethylammonium Chloride) hydrate

Storage

Argon charged,Room temperature

Shipped In

Normal

Descripción general

Nicotinic acetylcholine receptor (nAChR) forms a ligand-gated ion channel made up of four different subunits. Each subunit contains an extracellular amino-terminal domain (hydrophilic) and carboxylic terminal domain and four transmembrane domains. nAChR is an allosteric and transmembrane protein localized to the neuromuscular junction. 

Application：

Hexamethonium chloride has been used to block the responses of nicotinic receptors towards it agonists. It has also been used to study the mechanosensitivity of viscerofugal neurons.

Specifications

Sinónimos

Hexamethylenebis(trimethylammonium Chloride) hydrate | N, N, N, N', N', N'-Hexamethyl-1, 6-hexanediammonium Dichloride hydrate | Hexane-1, 6-bis(trimethylammonium Chloride) hydrate

Especificaciones y pureza

≥99%

Mecanismos bioquímicos y fisiológicos

Hexamethonium chloride preferentially blocks nicotinic receptors at autonomic ganglia, crosses blood-brain barrier only at high doses. Nicotinic acetylcholine receptor (nAChR) is responsible for cognitive functions. Blocking this receptor results in cognit

Condiciones de almacenamiento de almacenamiento

Argon charged, Room temperature

Enviado en

Normal

Pureza

≥99%

Nombres e identificadores

• CAS alternativo: 16986-49-5
• Peso molecular: 273.29(anhy)

Propiedades químicas y físicas

• Solubilidad: Soluble in water; Soluble in Ethanol; Insoluble in Ether,Chloroform
• Sensibilidad: Hygroscopic