≥98% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Information
HG-14-10-04 HG-14-10-04 is an inhibitor of ALK .
Targets
ALK
| ALogP | 5.241 |
|---|---|
| hba_count | 3 |
| Recuento HBD | 2 |
| Enlace rotable | 6 |
| Pubchem Sid | 504771434 |
|---|---|
| Pubchem Sid Url | https://pubchem.ncbi.nlm.nih.gov/substance/504771434 |
| Sonrisas canónicas | CN1CCN(CC1)C2CCN(CC2)C3=CC(=C(C=C3)NC4=NC=C(C(=N4)C5=CNC6=CC=CC=C65)Cl)OC |
| IUPAC Name | 5-chloro-4-(1H-indol-3-yl)-N-[2-methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]phenyl]pyrimidin-2-amine |
| InChIKey | HRYNCLKDKCPYBF-UHFFFAOYSA-N |
| INCHI | 1S/C29H34ClN7O/c1-35-13-15-37(16-14-35)20-9-11-36(12-10-20)21-7-8-26(27(17-21)38-2)33-29-32-19-24(30)28(34-29)23-18-31-25-6-4-3-5-22(23)25/h3-8,17-20,31H,9-16H2,1-2H3,(H,32,33,34) |
| Isómeros SMILES | CN1CCN(CC1)C2CCN(CC2)C3=CC(=C(C=C3)NC4=NC=C(C(=N4)C5=CNC6=CC=CC=C65)Cl)OC |
| Peso molecular | 532.08 |
| Reaxy-Rn | 22168451 |
| Reaxys-RN_link_address | https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=22168451&ln= |
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →Full quality attributes and acceptance criteria for this grade.
View spec sheet →Taxonomy Tree
| Kingdom | Organic compounds |
|---|---|
| Superclass | Organoheterocyclic compounds |
| Clase | Piperidines |
| Subclass | Phenylpiperidines |
| Intermediate Tree Nodes | Not available |
| Direct Parent | Phenylpiperidines |
| Alternative Parents | Indoles Methoxyanilines Aminophenyl ethers Anisoles Dialkylarylamines Methoxybenzenes Phenoxy compounds Aminopiperidines Halopyrimidines Aminopyrimidines and derivatives N-methylpiperazines Alkyl aryl ethers Aryl chlorides Substituted pyrroles Heteroaromatic compounds Trialkylamines Secondary amines Azacyclic compounds Hydrocarbon derivatives Organochlorides Organopnictogen compounds |
| Molecular Framework | Aromatic heteropolycyclic compounds |
| Substituents | Phenylpiperidine - Aminophenyl ether - Indole or derivatives - Indole - Methoxyaniline - Tertiary aliphatic/aromatic amine - Phenoxy compound - Phenol ether - Anisole - Methoxybenzene - Aniline or substituted anilines - Dialkylarylamine - Halopyrimidine - N-alkylpiperazine - N-methylpiperazine - Aminopyrimidine - 4-aminopiperidine - Alkyl aryl ether - Aryl chloride - Aryl halide - Monocyclic benzene moiety - 1,4-diazinane - Benzenoid - Piperazine - Pyrimidine - Substituted pyrrole - Pyrrole - Heteroaromatic compound - Tertiary amine - Tertiary aliphatic amine - Secondary amine - Azacycle - Ether - Amine - Organopnictogen compound - Organic oxygen compound - Organooxygen compound - Hydrocarbon derivative - Organohalogen compound - Organic nitrogen compound - Organochloride - Organonitrogen compound - Aromatic heteropolycyclic compound |
| Descripción | This compound belongs to the class of organic compounds known as phenylpiperidines. These are compounds containing a phenylpiperidine skeleton, which consists of a piperidine bound to a phenyl group. |
| External Descriptors | Not available |
Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Fecha | Articulo |
|---|---|---|---|
 I2205153 | Certificate of Analysis | Jun 09, 2025 | H413495 |
| I2205154 | Certificate of Analysis | Jun 09, 2025 | H413495 |
| I2205155 | Certificate of Analysis | Jun 09, 2025 | H413495 |
| I2205197 | Certificate of Analysis | Jun 09, 2025 | H413495 |
| I2205198 | Certificate of Analysis | Jun 09, 2025 | H413495 |
| Solubilidad | Solubility (25°C) In vitro DMSO: 10 mg/mL (18.79 mM); Water: Insoluble; Ethanol: Insoluble; |
|---|---|
| DMSO (mg/ml) Solubilidad máxima | 10 |
| DMSO (mM) Solubilidad máxima | 18.7941662907833 |
| Agua (mg/ml) Solubilidad máxima | ＜1 |
| Peso molecular | 532.100 g/mol |
| XLogP3 | 5.000 |
| Hydrogen Bond Donor Count | 2 |
| Hydrogen Bond Acceptor Count | 7 |
| Rotatable Bond Count | 6 |
| Exact Mass | 531.251 Da |
| Monoisotopic Mass | 531.251 Da |
| Topological Polar Surface Area | 72.600 Ų |
| Heavy Atom Count | 38 |
| Formal Charge | 0 |
| Complexity | 746.000 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| The total count of all stereochemical bonds | 0 |
| Covalently-Bonded Unit Count | 1 |
