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· · COA & SDS Disponible para cada producto · Same-day shipping on in-stock items HMR 1556 - Moligand™, ≥98%(HPLC) , Channel blocker of K v7.1, CAS No.223749-46-0, Channel blocker of K v7.1
GRADE & PURITY Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%(HPLC) Synonyms
(+)-HMR-1556 | (3R,4S)-(+)-N-(3-hydroxy-2,2-dimethyl-6-(4,4,4-trifluorobutoxy)chroman-4-yl)-N-methylmethanesulfonamide | NCGC00387222-01 | 4IF4R31066 | SCHEMBL4623436 | D85486 | Methanesulfonamide, N-((3R,4S)-3,4-dihydro-3-hydroxy-2,2-dimethyl-6-(4,4,4-tr
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Why this grade Moligand™, ≥98%(HPLC) Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
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Storage & shipping Room temperature Ships Normal Check lot-specific COA for exact specifications.
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Quality documents SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
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Literature proof Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Specifications Sinónimos
(+)-HMR-1556 | (3R, 4S)-(+)-N-(3-hydroxy-2, 2-dimethyl-6-(4, 4, 4-trifluorobutoxy)chroman-4-yl)-N-methylmethanesulfonamide | NCGC00387222-01 | 4IF4R31066 | SCHEMBL4623436 | D85486 | Methanesulfonamide, N-((3R, 4S)-3, 4-dihydro-3-hydroxy-2, 2-dimethyl-6-(4, 4, 4-tr
Especificaciones y pureza
Moligand™, ≥98%(HPLC)
Mecanismos bioquímicos y fisiológicos
Potent and selective Ikschannel blocker (IC50values are 10.5 and 34 nM in canine and guinea pig ventricular myocytes respectively). Selectively inhibits IKscurrents over IKr, IKI, Itoand L-type Ca2+channel currents. Also has little or no effect on Kv11.1
Condiciones de almacenamiento de almacenamiento
Room temperature
Tipo de acción
CHANNEL BLOCKER
Mecanismo de acción
Channel blocker of K v7.1
Nombres e identificadores Sonrisas canónicas CC1(C(C(C2=C(O1)C=CC(=C2)OCCCC(F)(F)F)N(C)S(=O)(=O)C)O)C IUPAC Name N-[(3R,4S)-3-hydroxy-2,2-dimethyl-6-(4,4,4-trifluorobutoxy)-3,4-dihydrochromen-4-yl]-N-methylmethanesulfonamide InChIKey SRZRLJWUQFIZRH-LSDHHAIUSA-N INCHI 1S/C17H24F3NO5S/c1-16(2)15(22)14(21(3)27(4,23)24)12-10-11(6-7-13(12)26-16)25-9-5-8-17(18,19)20/h6-7,10,14-15,22H,5,8-9H2,1-4H3/t14-,15+/m0/s1 Isómeros SMILES CC1([C@@H]([C@H](C2=C(O1)C=CC(=C2)OCCCC(F)(F)F)N(C)S(=O)(=O)C)O)C Peso molecular 411.44 Reaxy-Rn 9006043 Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=9006043&ln=
Documentation 📋 Safety Data Sheet (SDS) Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS → ✅ Certificate of Analysis (COA) Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA → 📊 Datasheet Quick-reference summary of product specifications and applications.
View datasheet → 🔬 Specification Sheet Full quality attributes and acceptance criteria for this grade.
View spec sheet →
Advanced Data Taxonomic Classification Kingdom Organic compounds Superclass Organoheterocyclic compounds Clase Benzopyrans Subclass 1-benzopyrans Intermediate Tree Nodes Not available Direct Parent 2,2-dimethyl-1-benzopyrans Alternative Parents Phenol ethers Alkyl aryl ethers Organosulfonamides Organic sulfonamides Aminosulfonyl compounds Secondary alcohols Oxacyclic compounds Organonitrogen compounds Organofluorides Organic oxides Hydrocarbon derivatives Alkyl fluorides Molecular Framework Aromatic heteropolycyclic compounds Substituents 2,2-dimethyl-1-benzopyran - Phenol ether - Alkyl aryl ether - Organic sulfonic acid amide - Organosulfonic acid amide - Benzenoid - Organic sulfonic acid or derivatives - Organosulfonic acid or derivatives - Sulfonyl - Aminosulfonyl compound - Secondary alcohol - Ether - Oxacycle - Organic nitrogen compound - Organic oxide - Alcohol - Organic oxygen compound - Organosulfur compound - Organooxygen compound - Organonitrogen compound - Organofluoride - Organohalogen compound - Hydrocarbon derivative - Alkyl fluoride - Alkyl halide - Aromatic heteropolycyclic compound Descripción This compound belongs to the class of organic compounds known as 2,2-dimethyl-1-benzopyrans. These are organic compounds containing a 1-benzopyran moiety that carries two methyl groups at the 2-position. External Descriptors Not available Data sources 1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.
Estructura 3D Objetivos asociados (humanos) Objetivos asociados (no humanos) Mecanismos de acción Certificados (CoA, COO, BSE/TSE y tabla de análisis) Propiedades químicas y físicas Solubilidad Solvent:DMSO, Max Conc. mg/mL: 41.14, Max Conc. mM: 100 Peso molecular 411.400 g/mol XLogP3 2.600 Hydrogen Bond Donor Count 1 Hydrogen Bond Acceptor Count 9 Rotatable Bond Count 6 Exact Mass 411.133 Da Monoisotopic Mass 411.133 Da Topological Polar Surface Area 84.500 Ų Heavy Atom Count 27 Formal Charge 0 Complexity 605.000 Isotope Atom Count 0 Defined Atom Stereocenter Count 2 Undefined Atom Stereocenter Count 0 Defined Bond Stereocenter Count 0 Undefined Bond Stereocenter Count 0 The total count of all stereochemical bonds 0 Covalently-Bonded Unit Count 1
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