HOIPIN-1 - ≥98% , CAS No.H413434

Cat. No.: H413434

GRADE & PURITY ≥98%

Synonyms

JTP-0819958 | HOIP inhibitor-1 | EX-A5121 | JTP 0819958 - HOIPIN-1 | Sodium (E)-2-(3-(2-methoxyphenyl)-3-oxoprop-1-enyl)benzoate | (2-[(1e)-3-(2-methoxyphenyl)-3-oxoprop-1-en-1yl] benzoic acid sodium salt

Storage

Store at 2-8°C,Protected from light,Argon charged

Shipped In

Wet ice

Descripción general

Product description：

HOIPIN-1 (JTP-0819958) is a selective inhibitor of linear ubiquitin chain assembly complex (LUBAC) (IC 50=2.8) μ M) It can inhibit NF-kB activation mediated by LUBAC in vitro

Information：

HOIPIN-1 (JTP-0819958, HOIP inhibitor-1) is a linear ubiquitin chain assembly complex (LUBAC) inhibitor with IC50 of 2.8 μM. HOIPIN-1 specifically generates Met1-linked linear ubiquitin chains through the ubiquitin ligase activity in HOIP, and activates the NF-kB pathway.

Specifications

Sinónimos

JTP-0819958 | HOIP inhibitor-1 | EX-A5121 | JTP 0819958 - HOIPIN-1 | Sodium (E)-2-(3-(2-methoxyphenyl)-3-oxoprop-1-enyl)benzoate | (2-[(1e)-3-(2-methoxyphenyl)-3-oxoprop-1-en-1yl] benzoic acid sodium salt

Especificaciones y pureza

≥98%

Mecanismos bioquímicos y fisiológicos

HOIPIN-1 (JTP-0819958, HOIP inhibitor-1) is a linear ubiquitin chain assembly complex (LUBAC) inhibitor with IC50 of 2.8 μM. HOIPIN-1 specifically generates Met1-linked linear ubiquitin chains through the ubiquitin ligase activity in HOIP, and activates t

Condiciones de almacenamiento de almacenamiento

Store at 2-8°C, Protected from light, Argon charged

Enviado en

Wet ice

Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.

Tipo de acción

INHIBITOR

Pureza

≥98%

Propiedades químicas y físicas

• Solubilidad: DMSO : 5 mg/mL (16.43 mM; Need ultrasonic)
• Sensibilidad: light ＆ moisture sensitive