GRADE & PURITY 10mM in DMSO

Synonyms

4-(2-(dimethylamino)ethyl)phenol

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

Descripción general

Information

Hordenine (N,N-dimethyl-4-hydroxyphenylethylamine) is a phenylethylamine alkaloid with antibacterial and antibiotic properties.
In vitro

Hordenine (N,N-dimethyl-4-hydroxyphenylethylamine) is a phenylethylamine alkaloid with antibacterial and antibiotic properties. It inhibits the uptake of norepinephrine in mammals, working as a stimulant. It is produced in nature by several varieties of plants in the family Cactaceae and by some in Acacia. Recent study shows that hordenine may be an effective inhibitor of hyperpigmentation. it inhibits melanogenesis by suppressing cAMP production, which is involved in the expression of melanogenesis-related proteins.

In vivo

LD50: Mice 113.5mg/kg
Cell Data

cell lines：

Concentrations：

Incubation Time：

Powder Purity:≥97%

Specifications

Sinónimos

4-(2-(dimethylamino)ethyl)phenol

Especificaciones y pureza

10mM in DMSO

Mecanismos bioquímicos y fisiológicos

Hordenine (N, N-dimethyl-4-hydroxyphenylethylamine) is a phenylethylamine alkaloid with antibacterial and antibiotic properties.

Condiciones de almacenamiento de almacenamiento

Store at -80°C

Enviado en

Dry ice packs + Cold packs

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Nombres e identificadores

• Isómeros SMILES: CN(C)CCC1=CC=C(C=C1)O
• WGK Alemania: 3
• Peso molecular: 165.23
• Beilstein: 2207615
• Reaxy-Rn: 2207615
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=2207615&ln=

Referencias

1. Jili Zou, Siran Wu, Bi Sheng, Jing An, Junhua Meng, Wang Xiong, Jiahan Tao, Wang Han, Lin Zhao, Hanlin Xu, Yonggang Chen.  (2022)  UPLC-Q-TOF-MS/MS analysis on the chemical composition of malts under different germination cycles and prepared with different processing methods.  FITOTERAPIA,      [PMID:36179899] [10.1016/j.fitote.2022.105313]

2. Yin Lujun, Shen Wang, Liu Jun-Sheng, Jia Ai-Qun.  (2022)  2-Hydroxymethyl-1-methyl-5-nitroimidazole, one siderophore inhibitor, occludes quorum sensing in Pseudomonas aeruginosa.  Frontiers in Cellular and Infection Microbiology,      [PMID:36159634] [10.3389/fcimb.2022.955952]