Factor VIIa, CAS No.65312-43-8

CAS: 65312-43-8 Cat. No.: H1442061

GRADE & PURITY Bioactive, ActiBioPure™, Native, High Performance, EnzymoPure™, ≥95%(SDS-PAGE), from Human plasma; Pre-lyophilization Protein Concentration: See COA

Accession #

P08709

Bioactivity

See COA

Descripción general

  Prepared from purified Human Factor VII using Human Factor XIIa. The Factor Xlla is removed using affinity chromatography. Purity is determined by SDS-PAGE. Human Factor VIIa reduces to 29,500 and 23,500 with the addition of 2-mercaptoethanol. Activity is determined via clotting assay. Factor Vlla, in the presence of calcium ions and Tissue factor, activates Factors IX and X to their enzymatically active forms, Factor IXa and Xa.

  Extinction Coefficient (1%) = 13.9

  The above protein was purified from Human plasma units that test negative for antibodies to HBc, HCV, HIV 1/2, HTLV-I/II, and non reactive for HBsAg, HIV-1 RNA, HCV RNA, HBV DNA and Syphilis by FDA approved tests. Donors are screened for CJD.

Specifications

Product Name

Factor VIIa, CAS No.65312-43-8

Sinónimos

Human Factor VIIa Native Protein | Coagulation Factor VIIa, Human Plasma | coagulation factor VIIa | Coagulation factor VII | F7 | SPCA

Grado

ActiBioPure™, Bioactive, High Performance, Native, EnzymoPure™

Especificaciones y pureza

Bioactive, ActiBioPure™, Native, High Performance, EnzymoPure™, ≥95%(SDS-PAGE), from Human plasma; Pre-lyophilization Protein Concentration: See COA

Mecanismos bioquímicos y fisiológicos

Initiates the extrinsic pathway of blood coagulation. Serine protease that circulates in the blood in a zymogen form. Factor VII is converted to factor VIIa by factor Xa, factor XIIa, factor IXa, or thrombin by minor proteolysis. In the presence of tissue

Bioactividad

See COA

Número de adhesión

P08709

Peso molecular previsto

50 kDa

CAS

65312-43-8

Número de la Comisión de Enzimas

EC 3.4.21.21

Tipo de molécula

Enzyme

Almacenamiento y envío

Concentración

from Human plasma; Pre-lyophilization Protein Concentration: See COA

Reconstitución

We suggest hydrating the protein with a good quality water to the original volume (See COA). After hydration aliquot into a useful (one time use) size and freeze at -80℃.

Condiciones de almacenamiento de almacenamiento

Store at 2-8°C

Enviado en

Wet ice

Estabilidad y almacenamiento

Store at 2-8℃ long term. Upon reconstitution, it is recommended to aliquot and freeze at -80℃.