Hydroxytyrosol(DOPET) - Moligand™,≥98% , CAS No.10597-60-1

CAS: 10597-60-1 Cat. No.: H107675 Peso molecular: 154.16 Beilstein Registry Number: 2208118 Número EC: 600-704-3
Disponible para pedir
GRADE & PURITY Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
Synonyms
dopet | HY-N0570 | AM20020163 | HYDROXYTYROSOL [INCI] | (1)Benzothieno(2,3-d)pyrimidin-4(1H)-one, 5,6,7,8-tetrahydro-2-methyl- | 3,4-dihydroxy-1-benzeneethanol | 4-(2-Hydroxy-ethyl)-benzene-1,2-diol | 4-(2-hydroxyethyl)benzene-1,2-diol | NSC-758468 | QEU0
Storage
Store at 2-8°C,Argon charged
Shipped In
Wet ice
 ·  off list, applied to all prices below.
Size
Estado
Price
Qty
100mg
H107675-100mg
2
12,90US$
250mg
H107675-250mg
2

15,90US$

19,90US$
Guardar 4,00 US$ (20.10%)
500mg
H107675-500mg
2

17,90US$

26,90US$
Guardar 9,00 US$ (33.46%)
1g
H107675-1g
2

19,90US$

29,90US$
Guardar 10,00 US$ (33.44%)
5g
H107675-5g
1
37,90US$
25g
H107675-25g
8-12 wks(?) Production requires sourcing of materials. We appreciate your patience and understanding.
113,90US$
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Why this grade

Moligand™,≥98% Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Store at 2-8°C,Argon charged Ships Wet ice Check lot-specific COA for exact specifications.

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Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 26 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Descripción general

Hydroxytyrosol (DOPET) is a phenol found in the olive oil. Hydroxytyrosol can alleviate oxidative stress and improve mitochondrial function, thereby exerting neuroprotective effects. Hydroxytyrosol can induce cancer cells apoptosis via inducing ROS production. Hydroxytyrosol shows antibacterial and antiviral effect. Hydroxytyrosol can be used for the researches of cancer, infection, inflammation, immunology, metabolic, neurological and cardiovascular disease, such as colon cancer, diabetes, Alzheimer's Disease and atherosclerosis.

Specifications

Sinónimos
dopet | HY-N0570 | AM20020163 | HYDROXYTYROSOL [INCI] | (1)Benzothieno(2, 3-d)pyrimidin-4(1H)-one, 5, 6, 7, 8-tetrahydro-2-methyl- | 3, 4-dihydroxy-1-benzeneethanol | 4-(2-Hydroxy-ethyl)-benzene-1, 2-diol | 4-(2-hydroxyethyl)benzene-1, 2-diol | NSC-758468 | QEU0
Especificaciones y pureza
Moligand™, ≥98%
Mecanismos bioquímicos y fisiológicos
Antioxidant agent. 5- and 12-lipoxygenase inhibitor (IC 50 values are 13 and 4.2 μM, respectively). Shows anti-inflammatory and antioxidant effects in vivo.
Condiciones de almacenamiento de almacenamiento
Store at 2-8°C, Argon charged
Enviado en
Wet ice
Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.
Grado
Moligand™
Nota
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
Pureza
≥98%
Nombres e identificadores
Sonrisas canónicasC1=CC(=C(C=C1CCO)O)O
IUPAC Name4-(2-hydroxyethyl)benzene-1,2-diol
InChIKeyJUUBCHWRXWPFFH-UHFFFAOYSA-N
INCHI1S/C8H10O3/c9-4-3-6-1-2-7(10)8(11)5-6/h1-2,5,9-11H,3-4H2
Isómeros SMILES C1=CC(=C(C=C1CCO)O)O
WGK Alemania 3
Peso molecular 154.16
Beilstein 2208118
Reaxy-Rn 2208118
Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=2208118&ln=

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Taxonomic Classification

Taxonomy Tree

KingdomOrganic compounds
SuperclassBenzenoids
ClasePhenols
SubclassTyrosols and derivatives
Intermediate Tree Nodes Not available
Direct ParentTyrosols
Alternative Parents Catechols  1-hydroxy-4-unsubstituted benzenoids  1-hydroxy-2-unsubstituted benzenoids  Benzene and substituted derivatives  Primary alcohols  Hydrocarbon derivatives  
Molecular FrameworkAromatic homomonocyclic compounds
Substituents Tyrosol - Catechol - 1-hydroxy-4-unsubstituted benzenoid - 1-hydroxy-2-unsubstituted benzenoid - Monocyclic benzene moiety - Organic oxygen compound - Hydrocarbon derivative - Primary alcohol - Organooxygen compound - Alcohol - Aromatic homomonocyclic compound
DescripciónThis compound belongs to the class of organic compounds known as tyrosols. These are organic aromatic compounds containing a phenethyl alcohol moiety that carries a hydroxyl group at the 4-position of the benzene group.
External Descriptors catechols - primary alcohol
Estructura 3D
Modelo de Estructura Química Interactiva





Objetivos asociados (humanos)
ALOX5 Tclin Arachidonate 5-lipoxygenase (6568 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
BACE1 Tchem Beta-secretase 1 (15641 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HT-29 (80576 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
PANC-1 (6144 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
PC-3 (62116 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SH-SY5Y (11521 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SK-BR-3 (5175 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SW480 (6023 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HeLa (62764 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
DG-75 (165 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Objetivos asociados (no humanos)
NA Neuraminidase (1107 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Pseudomonas aeruginosa (123386 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Staphylococcus aureus (210822 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Escherichia coli (133304 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Aspergillus niger (16508 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Bacillus subtilis (32866 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Candida albicans (78123 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mus musculus (284745 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Rattus norvegicus (775804 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Salmonella enterica (1497 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
MDCK (10148 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mecanismos de acción
Certificados (CoA, COO, BSE/TSE y tabla de análisis)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

36 results found

Lot NumberCertificate TypeFechaArticulo
F2603535Certificate of AnalysisJun 13, 2026 H107675
F2603534Certificate of AnalysisJun 13, 2026 H107675
F2603533Certificate of AnalysisJun 13, 2026 H107675
F2603532Certificate of AnalysisJun 13, 2026 H107675
F2603525Certificate of AnalysisJun 13, 2026 H107675
A2629038Certificate of AnalysisDec 16, 2025 H107675
L2503340Certificate of AnalysisDec 16, 2025 H107675
L2503339Certificate of AnalysisDec 16, 2025 H107675
L2503338Certificate of AnalysisDec 16, 2025 H107675
L2503337Certificate of AnalysisDec 16, 2025 H107675
L2503336Certificate of AnalysisDec 16, 2025 H107675
K2510365Certificate of AnalysisNov 13, 2025 H107675
G2416372Certificate of AnalysisJul 09, 2024 H107675
G2416374Certificate of AnalysisJul 09, 2024 H107675
G2416379Certificate of AnalysisJul 09, 2024 H107675
G2416380Certificate of AnalysisJul 09, 2024 H107675
G2416383Certificate of AnalysisJul 09, 2024 H107675
G2416386Certificate of AnalysisJul 09, 2024 H107675
H2525094Certificate of AnalysisJul 09, 2024 H107675
F2429235Certificate of AnalysisApr 25, 2024 H107675
F2429234Certificate of AnalysisApr 25, 2024 H107675
F2429232Certificate of AnalysisApr 25, 2024 H107675
F2429237Certificate of AnalysisApr 25, 2024 H107675
F2429233Certificate of AnalysisApr 25, 2024 H107675
F2429239Certificate of AnalysisApr 25, 2024 H107675
C1926148Certificate of AnalysisJan 26, 2023 H107675
J2221346Certificate of AnalysisSep 29, 2022 H107675
J2221347Certificate of AnalysisSep 29, 2022 H107675
J2221348Certificate of AnalysisSep 29, 2022 H107675
J2221349Certificate of AnalysisSep 29, 2022 H107675
H2205091Certificate of AnalysisJul 19, 2022 H107675
H2205090Certificate of AnalysisJul 19, 2022 H107675
H2205089Certificate of AnalysisJul 19, 2022 H107675
L2123104Certificate of AnalysisDec 27, 2021 H107675
B2218025Certificate of AnalysisDec 27, 2021 H107675
A2218024Certificate of AnalysisDec 27, 2021 H107675

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Propiedades químicas y físicas
Sensibilidadair sensitive
Índice de refracción1.58
Peso molecular154.160 g/mol
XLogP3-0.700
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count3
Rotatable Bond Count2
Exact Mass154.063 Da
Monoisotopic Mass154.063 Da
Topological Polar Surface Area60.700 Ų
Heavy Atom Count11
Formal Charge0
Complexity116.000
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
The total count of all stereochemical bonds0
Covalently-Bonded Unit Count1
Preguntas frecuentes y artículos
Citations of This Product
Referencias
1. Shuyan Han, Hongmei Hou, Yiren Zhang, Zhongxiang Fang, Yun Li, Le Zhang, Yandan Wang, Shijia Zhang, Hui Zhang, Qingzhe Jin, Gangcheng Wu, Xingguo Wang.  (2023)  Oleuropein and its hydrolysate from extra virgin olive oil inhibit breast cancer cells proliferation interfering with the PI3K-AKT signal pathway.  Journal of Functional Foods,      [PMID:] [10.1016/j.jff.2023.105880]
2. Chenchen Zhao, Yu Sha, Wei Zhuang, Yuan Rao, Jihang Zhang, Jinglan Wu, Tao Shen, Zhuotao Tan, Chenjie Zhu, Hongman Zhang, Hanjie Ying.  (2023)  Production of hydroxytyrosol from tyrosol via controllable oxidation with immobilized tyrosinase: A comparative study.  PROCESS BIOCHEMISTRY,      [PMID:] [10.1016/j.procbio.2023.06.017]
3. Fengxia Tang, Chuan Li, Xiaoran Yang, Jiandu Lei, Hongxia Chen, Changwei Zhang, Chengzhang Wang.  (2022)  Effect of Variety and Maturity Index on the Physicochemical Parameters Related to Virgin Olive Oil from Wudu (China).  Foods,  12  (1): (7).  [PMID:36613224] [10.3390/foods12010007]
4. Fan Wu, Fulin Tian, Zhou Jin, Jing Liu, Weiping Jin, Xuan Chen, Zhan Wang, Xiwu Jia, Benguo Liu, Lingyi Liu, Wangyang Shen.  (2021)  Antioxidant capacities of heat-treated wheat germ and extruded compounded bran.  CEREAL CHEMISTRY,  99  (3): (582-592).  [PMID:] [10.1002/cche.10520]
5. Xiaorong Zhang, Yun Jiang, Jiajie Mao, Xuekun Ren, Yinghui Ji, Yixin Mao, Yang Chen, Xiaoyu Sun, Yihuai Pan, Jianfeng Ma, Shengbin Huang.  (2021)  Hydroxytyrosol prevents periodontitis-induced bone loss by regulating mitochondrial function and mitogen-activated protein kinase signaling of bone cells.  FREE RADICAL BIOLOGY AND MEDICINE,      [PMID:34610362] [10.1016/j.freeradbiomed.2021.09.027]
6. Mingtao Zhao, Xulin Hong, Abdullah, Ruilian Yao, Yi Xiao.  (2020)  Rapid biosynthesis of phenolic glycosides and their derivatives from biomass-derived hydroxycinnamates.  GREEN CHEMISTRY,  23  (2): (838-847).  [PMID:] [10.1039/D0GC03595E]
7. Yang Li, Ying Peng, Ping Ma, Mengyue Wang, Chongsheng Peng, Pengfei Tu, Xiaobo Li.  (2019)  In vitro and in vivo metabolism of Cistanche tubulosa extract in normal and chronic unpredictable stress-induced depressive rats.  JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES,      [PMID:31352203] [10.1016/j.jchromb.2019.121728]
8. Jiahong Han, Min Dai, Yan Zhao, Enbo Cai, Lianxue Zhang, Xiaohuan Jia, Nian Sun, Xuan Fei, Hui Shu.  (2019)  Compatibility effects of ginseng and Ligustrum lucidum Ait herb pair on hematopoietic recovery in mice with cyclophosphamide-induced myelosuppression and its material basis.  Journal of Ginseng Research,      [PMID:32148411] [10.1016/j.jgr.2019.01.001]
9. Hao QIAN, Fang-Jun YU, Dan-Yi LU, Bao-Jian WU, Xing-Wang ZHANG, Huan WANG, Zhi-Guo MA.  (2018)  Identification of poliumoside metabolites in rat plasma, urine, bile, and intestinal bacteria with UPLC/Q-TOF-MS.  Chinese Journal of Natural Medicines,      [PMID:30502769] [10.1016/S1875-5364(18)30129-8]
10. Li-xing Wu, Yu-yu Xu, Zhi-jian Yang, Qing Feng.  (2018)  Hydroxytyrosol and olive leaf extract exert cardioprotective effects by inhibiting GRP78 and CHOP expression.  Journal of Biomedical Research,      [PMID:29760296] [10.7555/JBR.32.20170111]
11. Lingyi Liu, Zhou Jin, Min Wang, Wangyang Shen, Zhenzhou Zhu, Zhan Wang, Lianliang Liu.  (2018)  W/O Nano-Emulsions with Olive Leaf Phenolics Improved Oxidative Stability of Sacha Inchi Oil.  EUROPEAN JOURNAL OF LIPID SCIENCE AND TECHNOLOGY,  120  (5): (1700471).  [PMID:] [10.1002/ejlt.201700471]
12. Zhihong Wang, Chengzhang Wang, Changwei Zhang, Wenjun Li.  (2017)  Ultrasound-assisted enzyme catalyzed hydrolysis of olive waste and recovery of antioxidant phenolic compounds.  Innovative Food Science & Emerging Technologies,      [PMID:] [10.1016/j.ifset.2017.02.013]
13. Yang Li, Guisheng Zhou, Ying Peng, Pengfei Tu, Xiaobo Li.  (2015)  Screening and identification of three typical phenylethanoid glycosides metabolites from Cistanches Herba by human intestinal bacteria using UPLC/Q-TOF-MS.  JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS,      [PMID:26551535] [10.1016/j.jpba.2015.10.038]
14. Shiming Tang, Zhilin Ouyang, Ying Huo, Daocheng Liao, Zhiteng Zhang, Ying Lin, Suiping Zheng.  (2024)  An engineered dual-functional L-DOPA decarboxylase enables a minimized hydroxytyrosol cascade.  INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,      [PMID:39615727] [10.1016/j.ijbiomac.2024.138176]
15. Meiyu Gu, Jiahui Shi, Boya Zhang, Xibo Wang, Xu Wang.  (2024)  Covalent modification of soy protein isolates by hydroxytyrosol: Effects on structural and functional properties of adducts.  LWT-FOOD SCIENCE AND TECHNOLOGY,      [PMID:] [10.1016/j.lwt.2024.116041]
16. Tian Xia, Xiao-jiang Mao, Jian Zhang, Samad Rahimnejad, Kang-le Lu.  (2024)  Effects of quercetin and hydroxytyrosol supplementation in a high-fat diet on growth, lipid metabolism, and mitochondrial function in spotted seabass (Lateolabrax maculatus).  AQUACULTURE,      [PMID:] [10.1016/j.aquaculture.2023.740538]
17. Wen-Kai Liu, Xiu-Xin Ren, Lian Xu, Juan Lin.  (2025)  Modular cascade with engineered HpaB for efficient synthesis of hydroxytyrosol.  BIOORGANIC CHEMISTRY,      [PMID:39764921] [10.1016/j.bioorg.2025.108125]
18. Wen-Kai Liu, Bing-Mei Su, Xin-Qi Xu, Lian Xu, Juan Lin.  (2024)  Multienzymatic Cascade for Synthesis of Hydroxytyrosol via Two-Stage Biocatalysis.  JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY,      [PMID:38940657] [10.1021/acs.jafc.4c04228]
19. Yi Wang, Ruge Lin, Laiming Zhang, Suqing Lan, Xingqian Ye, Haibo Pan, Shiguo Chen.  (2024)  Oxygen influences in vitro assessment for phenolic compounds: Digestive stability, α-glucosidase inhibitory activity and bioavailability.  FOOD CHEMISTRY,      [PMID:39608122] [10.1016/j.foodchem.2024.142165]
20. Yang Li, Guisheng Zhou, Shihua Xing, Pengfei Tu, Xiaobo Li.  (2015)  Identification of Echinacoside Metabolites Produced by Human Intestinal Bacteria Using Ultraperformance Liquid Chromatography–Quadrupole Time-of-Flight Mass Spectrometry.  JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY,      [PMID:26186273] [10.1021/acs.jafc.5b02881]
21. Yang Li, Ying Peng, Mengyue Wang, Guisheng Zhou, Yulong Zhang, Xiaobo Li.  (2016)  Rapid screening and identification of the differences between metabolites of Cistanche deserticola and C. tubulosa water extract in rats by UPLC-Q-TOF-MS combined pattern recognition analysis.  JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS,      [PMID:27639339] [10.1016/j.jpba.2016.09.018]
22. Yang Li, Ying Peng, Mengyue Wang, Pengfei Tu, Xiaobo Li.  (2017)  Human Gastrointestinal Metabolism of the Cistanches Herba Water Extract in Vitro: Elucidation of the Metabolic Profile Based on Comprehensive Metabolite Identification in Gastric Juice, Intestinal Juice, Human Intestinal Bacteria, and Intestinal Microsomes.  JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY,      [PMID:28771352] [10.1021/acs.jafc.7b02829]
23. Hongyu Zhang, Guoshun Lin, Yang Yang, Yifei Wang, Xiushuo Yang, Guige Hou, Zhenbo Wang, Qingguo Meng, Yun Hou.  (2025)  Hydroxytyrosol Inhibits BPS-Induced NF-κB Signaling Pathway Activation, Mitigates Oxidative Stress, and Reduces Neuronal Apoptosis.  JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY,  39  (6): (e70303).  [PMID:40384030] [10.1002/jbt.70303]
24. Defan Zeng, Wenfeng Peng, Yupan Li, Fuquan Zhang, Xiaoxue Liao, Lusheng Liao.  (2025)  Effect of High-Efficiency Antioxidant on Storage Stability of Constant-Viscosity Natural Rubber.  POLYMER ENGINEERING AND SCIENCE,      [PMID:] [10.1002/pen.70220]
25. Hongyu Zhang, Guoshun Lin, Yifei Wang, Aihui Zheng, Hanlin Luo, Zhang Cao, Guige Hou, Yun Hou.  (2025)  Therapeutic potential of hydroxytyrosol against bisphenol S-induced toxicity to microglia via targeting cytochrome P450 1A1 (CYP1A1).  PHYTOMEDICINE,      [PMID:41330185] [10.1016/j.phymed.2025.157629]
26. Sitong Wu, Shiyao Li, Binglan Jia, Songge Cai, Qiang Cui, Xibo Wang, Xu Wang.  (2026)  Modulating dynamic interactions between soy protein isolate and hydroxytyrosol via pH-driven technology: Binding mechanism, structure, and functional characteristics.  LWT-FOOD SCIENCE AND TECHNOLOGY,      [PMID:] [10.1016/j.lwt.2026.119286]
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