Hyodeoxycholic acid - ≥98% , CAS No.83-49-8

CAS: 83-49-8 Cat. No.: H106315 Peso molecular: 392.57 Número EC: 201-483-2
Disponible para pedir
GRADE & PURITY ≥98%
Synonyms
SMP1_000164 | 3-alpha,6-alpha-Dihydroxy-5-beta-cholan-24-oic acid | 3alpha,6alpha-Dihydroxy-5beta-cholan-24-oic acid | Q5957042 | 3-.alpha.,6-.alpha.-Dihydroxy-5-.beta.-cholan-24-oic acid | 3alpha,6alpha-Dihydroxycholanic acid | 5-beta-Cholanic acid-3-alp
Storage
Store at 2-8°C,Argon charged
Shipped In
Wet ice
 ·  off list, applied to all prices below.
Size
Estado
Price
Qty
5g
H106315-5g
2
9,90US$
25g
H106315-25g
2
16,90US$
100g
H106315-100g
3
37,90US$
500g
H106315-500g
2
121,90US$
Enter a quantity for the sizes you want to add.
🧪

Why this grade

≥98% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Store at 2-8°C,Argon charged Ships Wet ice Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 11 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Specifications

Sinónimos
SMP1_000164 | 3-alpha, 6-alpha-Dihydroxy-5-beta-cholan-24-oic acid | 3alpha, 6alpha-Dihydroxy-5beta-cholan-24-oic acid | Q5957042 | 3-.alpha., 6-.alpha.-Dihydroxy-5-.beta.-cholan-24-oic acid | 3alpha, 6alpha-Dihydroxycholanic acid | 5-beta-Cholanic acid-3-alp
Especificaciones y pureza
≥98%
Mecanismos bioquímicos y fisiológicos
Secondary bile acid. Lowers LDL-cholesterol concentration. Inhibits atherosclerotic lesion formation in vivo .
Condiciones de almacenamiento de almacenamiento
Store at 2-8°C, Argon charged
Enviado en
Wet ice
Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.
Nota
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
Pureza
≥98%
Propiedades del producto
ALogP4.9
Nombres e identificadores
Pubchem Sid504763477
Pubchem Sid Urlhttps://pubchem.ncbi.nlm.nih.gov/substance/504763477
Sonrisas canónicasCC(CCC(=O)O)C1CCC2C1(CCC3C2CC(C4C3(CCC(C4)O)C)O)C
IUPAC Name(4R)-4-[(3R,5R,6S,8S,9S,10R,13R,14S,17R)-3,6-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoic acid
InChIKeyDGABKXLVXPYZII-SIBKNCMHSA-N
INCHI1S/C24H40O4/c1-14(4-7-22(27)28)17-5-6-18-16-13-21(26)20-12-15(25)8-10-24(20,3)19(16)9-11-23(17,18)2/h14-21,25-26H,4-13H2,1-3H3,(H,27,28)/t14-,15-,16+,17-,18+,19+,20+,21+,23-,24-/m1/s1
Isómeros SMILES C[C@H](CCC(=O)O)[C@H]1CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2C[C@@H]([C@H]4[C@@]3(CC[C@H](C4)O)C)O)C
WGK Alemania 3
Peso molecular 392.57
Reaxy-Rn 2950246
Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=2950246&ln=

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Taxonomic Classification

Taxonomy Tree

KingdomOrganic compounds
SuperclassLipids and lipid-like molecules
ClaseSteroids and steroid derivatives
SubclassBile acids, alcohols and derivatives
Intermediate Tree Nodes Hydroxy bile acids, alcohols and derivatives
Direct ParentDihydroxy bile acids, alcohols and derivatives
Alternative Parents 6-hydroxysteroids  3-alpha-hydroxysteroids  Secondary alcohols  Cyclic alcohols and derivatives  Monocarboxylic acids and derivatives  Carboxylic acids  Organic oxides  Hydrocarbon derivatives  Carbonyl compounds  
Molecular FrameworkAliphatic homopolycyclic compounds
Substituents Dihydroxy bile acid, alcohol, or derivatives - 3-hydroxysteroid - 3-alpha-hydroxysteroid - 6-hydroxysteroid - Hydroxysteroid - Cyclic alcohol - Secondary alcohol - Carboxylic acid - Carboxylic acid derivative - Monocarboxylic acid or derivatives - Organooxygen compound - Organic oxygen compound - Hydrocarbon derivative - Organic oxide - Carbonyl group - Alcohol - Aliphatic homopolycyclic compound
DescripciónThis compound belongs to the class of organic compounds known as dihydroxy bile acids, alcohols and derivatives. These are compounds containing or derived from a bile acid or alcohol, and which bears exactly two carboxylic acid groups.
External Descriptors C24 bile acids, alcohols, and derivatives
Estructura 3D
Modelo de Estructura Química Interactiva





Objetivos asociados (humanos)
VDR Tclin Vitamin D receptor (26531 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
UGT2B7 Tchem UDP-glucuronosyltransferase 2B7 (787 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
UGT2B17 Tbio UDP-glucuronosyltransferase 2B17 (197 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
GPBAR1 Tchem G-protein coupled bile acid receptor 1 (1723 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
UGT2B4 Tbio UDP-glucuronosyltransferase 2B4 (139 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
UGT2B10 Tbio UDP-glucuronosyltransferase 2B10 (42 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
UGT2B15 Tbio UDP-glucuronosyltransferase 2B15 (172 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
UGT1A1 Tchem UDP-glucuronosyltransferase 1-1 (448 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
UGT1A7 Tbio UDP-glucuronosyltransferase 1-7 (106 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
UGT1A8 Tbio UDP-glucuronosyltransferase 1-8 (233 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
UGT1A10 Tbio UDP-glucuronosyltransferase 1-10 (257 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Objetivos asociados (no humanos)
Hdac6 Histone deacetylase 6 (222 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Clostridioides difficile (2968 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Trypanosoma brucei brucei (13300 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Plasmodium falciparum (966862 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Slc10a1 Bile acid transporter (65 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
rep Replicase polyprotein 1ab (378 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Slco1a1 Solute carrier organic anion transporter family member 1A1 (265 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mecanismos de acción
Certificados (CoA, COO, BSE/TSE y tabla de análisis)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

20 results found

Lot NumberCertificate TypeFechaArticulo
E2615104Certificate of AnalysisMay 25, 2026 H106315
J2231122Certificate of AnalysisMay 09, 2026 H106315
F2428011Certificate of AnalysisApr 02, 2026 H106315
D2411474Certificate of AnalysisJan 21, 2026 H106315
E2512037Certificate of AnalysisMay 15, 2025 H106315
A2306697Certificate of AnalysisOct 24, 2024 H106315
A2306601Certificate of AnalysisOct 24, 2024 H106315
A2306574Certificate of AnalysisOct 24, 2024 H106315
A2306526Certificate of AnalysisOct 24, 2024 H106315
A2306607Certificate of AnalysisOct 17, 2024 H106315
A2306563Certificate of AnalysisOct 17, 2024 H106315
A2306551Certificate of AnalysisOct 17, 2024 H106315
D2411475Certificate of AnalysisMar 15, 2024 H106315
G2504069Certificate of AnalysisMar 15, 2024 H106315
A2206660Certificate of AnalysisOct 11, 2023 H106315
A2207162Certificate of AnalysisOct 11, 2023 H106315
A2207161Certificate of AnalysisOct 11, 2023 H106315
G2115217Certificate of AnalysisApr 17, 2023 H106315
G2115218Certificate of AnalysisApr 17, 2023 H106315
A2306552Certificate of AnalysisNov 09, 2022 H106315

Show more ⌵

Propiedades químicas y físicas
Punto de fusión (°C)200-201°C
Peso molecular392.600 g/mol
XLogP34.900
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count4
Rotatable Bond Count4
Exact Mass392.293 Da
Monoisotopic Mass392.293 Da
Topological Polar Surface Area77.800 Ų
Heavy Atom Count28
Formal Charge0
Complexity605.000
Isotope Atom Count0
Defined Atom Stereocenter Count10
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
The total count of all stereochemical bonds0
Covalently-Bonded Unit Count1
Citations of This Product
Referencias
1. Jiaxin Li, Yuqi Chen, Rui Li, Xianglong Zhang, Tao Chen, Fengyi Mei, Ruofan Liu, Meiling Chen, Yue Ge, Hongbin Hu, Rongjuan Wei, Zhenfeng Chen, Hongying Fan, Zhenhua Zeng, Yongqiang Deng, Haihua Luo, Shuiwang Hu, Shumin Cai, Feng Wu, Nengxian Shi, Zhang Wang, Yunong Zeng, Ming Xie, Yong Jiang, Zhongqing Chen, Wei Jia, Peng Chen.  (2023)  Gut microbial metabolite hyodeoxycholic acid targets the TLR4/MD2 complex to attenuate inflammation and protect against sepsis.  MOLECULAR THERAPY,      [PMID:36698311] [10.1016/j.ymthe.2023.01.018]
2. Jiating Zheng, Xiaoru Peng, Taifeng Zhu, Shuyao Huang, Chao Chen, Guosheng Chen, Shuqin Liu, Gangfeng Ouyang.  (2022)  Detection of bile acids in small volume human bile samples via an amino metal-organic framework composite based solid-phase microextraction probe.  JOURNAL OF CHROMATOGRAPHY A,      [PMID:36345074] [10.1016/j.chroma.2022.463634]
3. Ding Shen, Wei Hu, Suqing Zhao, Chuanbin Mao.  (2021)  Rapid Naked-Eye Detection of a Liver Disease Biomarker by Discovering Its Monoclonal Antibody to Functionalize Engineered Red-Colored Bacteria Probes.  ACS Omega,      [PMID:34870023] [10.1021/acsomega.1c04779]
4. Qiyi He, Yanxiong Fang, Huiyi Yang, Ding Shen, Yingshan Chen, Yingying Zhong, Xiangguang Li, Sergei A. Eremin, Xiping Cui, Suqing Zhao.  (2021)  Enhanced performance of a surface plasmon resonance-based immunosensor for the detection of glycocholic acid.  Analytical Methods,  13  (16): (1919-1924).  [PMID:33913980] [10.1039/D1AY00357G]
5. Ma Chongyang, Wang Xueqian, Xu Tian, Zhang Shuang, Liu Shuling, Zhai Changming, Wang Zisong, Mu Jie, Li Changxiang, Cheng Fafeng, Wang Qingguo.  (2020)  An Integrative Pharmacology-Based Analysis of Refined Qingkailing Injection Against Cerebral Ischemic Stroke: A Novel Combination of Baicalin, Geniposide, Cholic Acid, and Hyodeoxycholic Acid.  Frontiers in Pharmacology,      [PMID:32457601] [10.3389/fphar.2020.00519]
6. Yang Yang, Yang Cao, Yonghong Hu, Qi Zhang, Wenge Yang, Fei Shen.  (2015)  Thermodynamic analysis and correlation of solid–liquid equilibrium of hyodeoxycholic acid in ethanol + (acetone, ethyl acetate) binary solvent mixtures.  JOURNAL OF MOLECULAR LIQUIDS,      [PMID:] [10.1016/j.molliq.2015.07.005]
7. Juan Zhou, Yi-Qiao Xu, Sheng-Ya Guo, Chun-Qi Li.  (2014)  Rapid analysis of hypolipidemic drugs in a live zebrafish assay.  JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS,      [PMID:25497901] [10.1016/j.vascn.2014.12.002]
8. Yang Yang, Yonghong Hu, Qi Zhang, Limin Cheng, Cuicui Cao, Wenge Yang, Fei Shen.  (2014)  Experimental measurement and thermodynamic models for solid–liquid equilibrium of hyodeoxycholic acid in different organic solvents.  JOURNAL OF MOLECULAR LIQUIDS,      [PMID:] [10.1016/j.molliq.2014.12.007]
9. Hao Zhi, Zhongyan Wang, Xinyue Zhu, Wenhan Wu, Lu Yang, Yidong Dai, Zehua Wang, Ling Jiang, Yongmei Tan, Xiaodong Liu, Li Liu.  (2025)  Chronic liver injury decreases levels of cerebral carnitine and acetylcarnitine in rats partly due to the downregulation of OCTs and OCTN2 at the blood-brain barrier.  DRUG METABOLISM AND DISPOSITION,      [PMID:40300306] [10.1016/j.dmd.2025.100072]
10. Cui Xiping, He Qiyi, Yang Huiyi, Chen Yingshan, Shen Ding, Eremin Sergei A., Mu Yunping, Zhao Suqing.  (2021)  Development of enzyme-free single-step immunoassays for glycocholic acid based on palladium nanoparticle-mediated signal generation.  ANALYTICAL AND BIOANALYTICAL CHEMISTRY,  413  (23): (5733-5742).  [PMID:34476526] [10.1007/s00216-021-03548-5]
11. Zhiye Yan, Weiwei Tang, Bin Li.  (2025)  Expanding Metabolome Coverage in LC–MS/MS Analysis through Hydralazine-Based Multifunctional Derivatization.  ANALYTICAL CHEMISTRY,      [PMID:41277254] [10.1021/acs.analchem.5c02101]
Calculadoras de soluciones
Reseñas

Reseñas de cliente

Shall we send you a message when we have discounts available?

Remind me later

Thank you! Please check your email inbox to confirm.

Oops! Notifications are disabled.