BET bromodomain inhibitor; blocks recruitment of BET to chromatin. Induces apoptosis and G0/G1cell cycle arrest in MLL-fusion leukemic cell linesin vitro(IC50values are 15, 26, 120 and 192 nM for NOMO1, MV4;11, MOLM13 and RS4;11 cell lines respectively);
Condiciones de almacenamiento de almacenamiento
Store at -20°C
Enviado en
Ice chest + Ice pads
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Solvent:DMSO, Max Conc. mg/mL: 41.54, Max Conc. mM: 100; Solvent:ethanol, Max Conc. mg/mL: 41.54, Max Conc. mM: 100; Solvent:water, Max Conc. mg/mL: 48.84, Max Conc. mM: 100
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