I-BET 151 dihydrochloride - ≥98%(HPLC) , CAS No.1883545-47-8

CAS: 1883545-47-8 Cat. No.: I287715 Peso molecular: 488.37 PubChem CID: 121513850
Disponible para pedir
GRADE & PURITY ≥98%(HPLC)
Synonyms
I-BET151 dihydrochloride | GSK1210151A dihydrochloride | 7-(3,5-Dimethyl-4-isoxazolyl)-1,3-dihydroxy-8-methoxy-1-[(1R)-1-(2-pyridinyl)ethyl]-2H-imidazo[4,5-c]quinolin-2-one dihydrochloride
Storage
Store at -20°C
Shipped In
Ice chest + Ice pads
 ·  off list, applied to all prices below.
Size
Estado
Price
Qty
5mg
I287715-5mg
2
157,90US$
10mg
I287715-10mg
2
242,90US$
25mg
I287715-25mg
2
545,90US$
50mg
I287715-50mg
2
992,90US$
Enter a quantity for the sizes you want to add.
🧪

Why this grade

≥98%(HPLC) for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Specifications

Sinónimos
I-BET151 dihydrochloride | GSK1210151A dihydrochloride | 7-(3, 5-Dimethyl-4-isoxazolyl)-1, 3-dihydroxy-8-methoxy-1-[(1R)-1-(2-pyridinyl)ethyl]-2H-imidazo[4, 5-c]quinolin-2-one dihydrochloride
Especificaciones y pureza
≥98%(HPLC)
Mecanismos bioquímicos y fisiológicos
BET bromodomain inhibitor; blocks recruitment of BET to chromatin. Induces apoptosis and G0/G1cell cycle arrest in MLL-fusion leukemic cell linesin vitro(IC50values are 15, 26, 120 and 192 nM for NOMO1, MV4;11, MOLM13 and RS4;11 cell lines respectively);
Condiciones de almacenamiento de almacenamiento
Store at -20°C
Enviado en
Ice chest + Ice pads
Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.
Tipo de acción
INHIBITOR
Pureza
≥98%(HPLC)
Nombres e identificadores
Pubchem Sid488202689
Pubchem Sid Urlhttps://pubchem.ncbi.nlm.nih.gov/substance/488202689
Sonrisas canónicasCC1=C(C(=NO1)C)C2=C(C=C3C(=C2)N=CC4=C3N(C(=O)N4)C(C)C5=CC=CC=N5)OC.Cl.Cl
IUPAC Name7-(3,5-dimethyl-1,2-oxazol-4-yl)-8-methoxy-1-[(1R)-1-pyridin-2-ylethyl]-3H-imidazo[4,5-c]quinolin-2-one;dihydrochloride
InChIKeyUFLKDZBLUNJNJS-FFXKMJQXSA-N
INCHI1S/C23H21N5O3.2ClH/c1-12-21(14(3)31-27-12)16-9-18-15(10-20(16)30-4)22-19(11-25-18)26-23(29)28(22)13(2)17-7-5-6-8-24-17;;/h5-11,13H,1-4H3,(H,26,29);2*1H/t13-;;/m1../s1
PubChem CID 121513850
Peso molecular 488.37

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Estructura 3D
Modelo de Estructura Química Interactiva





Certificados (CoA, COO, BSE/TSE y tabla de análisis)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

8 results found

Lot NumberCertificate TypeFechaArticulo
B2328689Certificate of AnalysisDec 12, 2025 I287715
B2328692Certificate of AnalysisDec 12, 2025 I287715
B2328693Certificate of AnalysisDec 12, 2025 I287715
B2328706Certificate of AnalysisDec 12, 2025 I287715
B2328707Certificate of AnalysisDec 12, 2025 I287715
B2328708Certificate of AnalysisDec 12, 2025 I287715
B2328712Certificate of AnalysisDec 12, 2025 I287715
B2328795Certificate of AnalysisDec 12, 2025 I287715
Propiedades químicas y físicas
SolubilidadSolvent:DMSO, Max Conc. mg/mL: 41.54, Max Conc. mM: 100; Solvent:ethanol, Max Conc. mg/mL: 41.54, Max Conc. mM: 100; Solvent:water, Max Conc. mg/mL: 48.84, Max Conc. mM: 100
Calculadoras de soluciones
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