GRADE & PURITYMoligand™?Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools.10 mM in DMSO
Moligand™, 10 mM in DMSO Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
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Storage & shipping
Store at -80°C Ships Dry ice packs + Cold packs Check lot-specific COA for exact specifications.
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Quality documents
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
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Literature proof
Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Descripción general
ICA-121431 is a nanomolar potent and broad-spectrum voltage-gated sodium channel (Na v ) blocker, shows equipotent selectivity for human Na v 1.1 and Na v 1.3 subtypes with IC 50 values of 13 nM and 23 nM, respectively. ICA-121431 shows less potent inhibition of Na v 1.2 ( IC 50 =240 nM) and 1,000 fold selectivity against Na v 1.4, Na v 1.6, and the TTX-resistant human Na v 1.5 and Na v 1.8 channels ( IC 50 s >10 μM).
Specifications
Especificaciones y pureza
Moligand™, 10 mM in DMSO
Condiciones de almacenamiento de almacenamiento
Store at -80°C
Enviado en
Dry ice packs + Cold packs
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