Icariin - 10mM in DMSO , CAS No.489-32-7

CAS: 489-32-7 Cat. No.: I407996 Fórmula: C₃₃H₄₀O₁₅ Peso molecular: 676.66 Número EC: 610-440-0 PubChem CID: 5318997

CALIDAD & PUREZA 10mM in DMSO

Synonyms

4H-1-Benzopyran-4-one, 3-[(6-deoxy-α-L-mannopyranosyl)oxy]-7-(β-D-glucopyranosyloxy)-5-hydroxy-2-(4-methoxyphenyl)-8-(3-methyl-2-buten-1-yl)-

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

Descripción general

Information

Icariin is a cGMP-specificPDE5inhibitor withIC50of 0.432 μM, 167-fold more selective for PDE5 than PDE4.
In vitro

In vivo

Cell Data

cell lines：PC-3 cells

Concentrations：

Incubation Time：

Powder Purity:≥97%

Especificaciones

Sinónimos

4H-1-Benzopyran-4-one, 3-[(6-deoxy-α-L-mannopyranosyl)oxy]-7-(β-D-glucopyranosyloxy)-5-hydroxy-2-(4-methoxyphenyl)-8-(3-methyl-2-buten-1-yl)-

Especificaciones y pureza

10mM in DMSO

Mecanismos bioquímicos y fisiológicos

Icariin is a cGMP-specific PDE5 inhibitor with IC50 of 0.432 μM, 167-fold more selective for PDE5 than PDE4.

Condiciones de almacenamiento de almacenamiento

Store at -80°C

Enviado en

Dry ice packs + Cold packs

Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.

Nombres e identificadores

Isómeros SMILES

C[C@H]1[C@@H]([C@H]([C@H]([C@@H](O1)OC2=C(OC3=C(C2=O)C(=CC(=C3CC=C(C)C)O[C@H]4[C@@H]([C@H]([C@@H]([C@H](O4)CO)O)O)O)O)C5=CC=C(C=C5)OC)O)O)O

WGK Alemania

3

PubChem CID

5318997

Peso molecular

676.66

Propiedades químicas y físicas

• Solubilidad: Solubility (25°C) In vitro DMSO: 74 mg/mL (200.29 mM)
• Rotación específica [α]: -84° (C=1,Pyridine)
• Punto de fusión (°C): 235 - 239°C

Preguntas frecuentes

How should this product be stored?

Store at ?80 °C. Ultra-low temperature storage is required to maintain the specified shelf life.

How is this product shipped?

This product ships frozen with dry ice and cold packs. Unpack on arrival and transfer it to the storage condition stated above; handle dry ice with insulated gloves in a ventilated area.

What are the CAS number, molecular formula and molecular weight?

The CAS Number is 489-32-7, the molecular formula is C33H40O15, and the molecular weight is 676.66 g/mol.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.