≥98% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Protected from light,Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Information
Indophagolin is a potent, indoline-containing autophagy inhibitor with IC50 of 140 nM. Indophagolin antagonizes the purinergic receptor P2X4, P2X1 and P2X3 with IC50 of 2.71 μM, 2.40 μM and 3.49 μM, respectively. Indophagolin also antagonizes the Gq-protein-coupled P2Y4, P2Y6, and P2Y11 receptors with IC50 of 3.4~15.4 μM. Indophagolin has a strong antagonistic effect on serotonin receptor 5-HT6 with IC50 of 1.0 μM.
| Pubchem Sid | 488201297 |
|---|---|
| Pubchem Sid Url | https://pubchem.ncbi.nlm.nih.gov/substance/488201297 |
| Sonrisas canónicas | C1CC1C(=O)N2CCC3=CC(=C(C=C32)S(=O)(=O)NC4=CC(=C(C=C4)Cl)C(F)(F)F)Br |
| IUPAC Name | 5-bromo-N-[4-chloro-3-(trifluoromethyl)phenyl]-1-(cyclopropanecarbonyl)-2,3-dihydroindole-6-sulfonamide |
| InChIKey | OGXJZCDFFBDSJJ-UHFFFAOYSA-N |
| INCHI | 1S/C19H15BrClF3N2O3S/c20-14-7-11-5-6-26(18(27)10-1-2-10)16(11)9-17(14)30(28,29)25-12-3-4-15(21)13(8-12)19(22,23)24/h3-4,7-10,25H,1-2,5-6H2 |
| Isómeros SMILES | C1CC1C(=O)N2CCC3=CC(=C(C=C32)S(=O)(=O)NC4=CC(=C(C=C4)Cl)C(F)(F)F)Br |
| Peso molecular | 523.75 |
| Reaxy-Rn | 46063456 |
| Reaxys-RN_link_address | https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=46063456&ln= |
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →Full quality attributes and acceptance criteria for this grade.
View spec sheet →Taxonomy Tree
| Kingdom | Organic compounds |
|---|---|
| Superclass | Benzenoids |
| Clase | Benzene and substituted derivatives |
| Subclass | Trifluoromethylbenzenes |
| Intermediate Tree Nodes | Not available |
| Direct Parent | Trifluoromethylbenzenes |
| Alternative Parents | Indoles and derivatives N-acylpyrrolidines Chlorobenzenes N-acyl amines Cyclopropanecarboxylic acids and derivatives Tertiary carboxylic acid amides Sulfonyls Organosulfonic acids and derivatives Vinyl chlorides Vinyl bromides Chloroalkenes Bromoalkenes Azacyclic compounds Organopnictogen compounds Organooxygen compounds Organonitrogen compounds Organofluorides Organochlorides Organobromides Organic oxides Hydrocarbon derivatives Alkyl fluorides |
| Molecular Framework | Aromatic heteropolycyclic compounds |
| Substituents | Trifluoromethylbenzene - Indole or derivatives - N-acylpyrrolidine - Halobenzene - Chlorobenzene - N-acyl-amine - Cyclopropanecarboxylic acid or derivatives - Tertiary carboxylic acid amide - Sulfonyl - Organosulfonic acid or derivatives - Organic sulfonic acid or derivatives - Pyrrolidine - Carboxamide group - Azacycle - Chloroalkene - Bromoalkene - Haloalkene - Organoheterocyclic compound - Vinyl halide - Vinyl chloride - Vinyl bromide - Carboxylic acid derivative - Organic nitrogen compound - Organic oxygen compound - Organopnictogen compound - Organic oxide - Hydrocarbon derivative - Organosulfur compound - Organooxygen compound - Organonitrogen compound - Organofluoride - Organochloride - Organobromide - Organohalogen compound - Alkyl halide - Alkyl fluoride - Aromatic heteropolycyclic compound |
| Descripción | This compound belongs to the class of organic compounds known as trifluoromethylbenzenes. These are organofluorine compounds that contain a benzene ring substituted with one or more trifluoromethyl groups. |
| External Descriptors | Not available |
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Fecha | Articulo |
|---|---|---|---|
 C2328979 | Certificate of Analysis | Jan 26, 2026 | I413408 |
| C2328930 | Certificate of Analysis | Jan 26, 2026 | I413408 |
| C2328928 | Certificate of Analysis | Jan 26, 2026 | I413408 |
| C2328920 | Certificate of Analysis | Jan 26, 2026 | I413408 |
| C2328916 | Certificate of Analysis | Jan 26, 2026 | I413408 |
| C2328913 | Certificate of Analysis | Jan 26, 2026 | I413408 |
| C2328900 | Certificate of Analysis | Jan 26, 2026 | I413408 |
| C2328887 | Certificate of Analysis | Jan 26, 2026 | I413408 |
| C2328859 | Certificate of Analysis | Jan 26, 2026 | I413408 |
| C2328856 | Certificate of Analysis | Jan 26, 2026 | I413408 |
| C2328845 | Certificate of Analysis | Jan 26, 2026 | I413408 |
| C2328837 | Certificate of Analysis | Jan 26, 2026 | I413408 |
| C2328836 | Certificate of Analysis | Jan 26, 2026 | I413408 |
| C2328775 | Certificate of Analysis | Jan 26, 2026 | I413408 |
| C2320979 | Certificate of Analysis | Jan 05, 2023 | I413408 |
| C2519775 | Certificate of Analysis | Jan 05, 2023 | I413408 |
| Sensibilidad | Light sensitive |
|---|---|
| Peso molecular | 523.799 g/mol |
| XLogP3 | 4.500 |
| Hydrogen Bond Donor Count | 1 |
| Hydrogen Bond Acceptor Count | 7 |
| Rotatable Bond Count | 4 |
| Exact Mass | 521.963 Da |
| Monoisotopic Mass | 521.963 Da |
| Topological Polar Surface Area | 74.900 Ų |
| Heavy Atom Count | 30 |
| Formal Charge | 0 |
| Complexity | 774.000 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| The total count of all stereochemical bonds | 0 |
| Covalently-Bonded Unit Count | 1 |
