INDY - ≥98% , CAS No.1169755-45-6

CAS: 1169755-45-6 Cat. No.: I275280 Peso molecular: 235.3

GRADE & PURITY ≥98%

Synonyms

(1Z)-1-(3-Ethyl-5-hydroxy-2(3H)-benzothiazolylidene)-2-propanone | (Z)-1-(3-ethyl-5-hydroxybenzo[d]thiazol-2(3H)-ylidene)propan-2-one

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

Descripción general

Shipped at Room Temperature. Store at +4°C short term (1-2 weeks). Store at -20°C.

Specifications

Sinónimos

(1Z)-1-(3-Ethyl-5-hydroxy-2(3H)-benzothiazolylidene)-2-propanone | (Z)-1-(3-ethyl-5-hydroxybenzo[d]thiazol-2(3H)-ylidene)propan-2-one

Especificaciones y pureza

≥98%

Mecanismos bioquímicos y fisiológicos

Potent DYRK1A/B inhibitor (IC 50 values are 0.23 and 0.24\xa0µM for DYRK1B and DYRK1A respectively). Also inhibits DYRK2, DTRK4, CLK1, CLK4, casein kinase 1 and PIM1 (> 90% inhibition at 10 μM).

Condiciones de almacenamiento de almacenamiento

Store at -20°C

Enviado en

Ice chest + Ice pads

Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.

Tipo de acción

INHIBITOR

Nota

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

Pureza

≥98%

Nombres e identificadores

• Pubchem Sid: 488202143
• Pubchem Sid Url: https://pubchem.ncbi.nlm.nih.gov/substance/488202143
• Sonrisas canónicas: CCN1C2=C(C=CC(=C2)O)SC1=CC(=O)C
• IUPAC Name: 1-(3-ethyl-5-hydroxy-1,3-benzothiazol-2-ylidene)propan-2-one
• InChIKey: GCSZJMUFYOAHFY-UHFFFAOYSA-N
• INCHI: 1S/C12H13NO2S/c1-3-13-10-7-9(15)4-5-11(10)16-12(13)6-8(2)14/h4-7,15H,3H2,1-2H3
• Isómeros SMILES: CCN1C2=C(C=CC(=C2)O)SC1=CC(=O)C
• Peso molecular: 235.3
• Reaxy-Rn: 28418243
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=28418243&ln=

Propiedades químicas y físicas

• Solubilidad: Soluble in DMSO to 100 mM