IR-783 - Moligand™, 10 mM in DMSO , CAS No.115970-66-6

CAS: 115970-66-6 Cat. No.: I1496756 Peso molecular: 749.35 Número EC: 812-288-2
Disponible para pedir
GRADE & PURITY Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10 mM in DMSO
Storage
Desiccated,Store at -80°C
Shipped In
Dry ice packs + Cold packs
 ·  off list, applied to all prices below.
Size
Estado
Price
Qty
1ml
I1496756-1ml
8-12 wks(?) Production requires sourcing of materials. We appreciate your patience and understanding.
28,90US$
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Why this grade

Moligand™, 10 mM in DMSO Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Desiccated,Store at -80°C Ships Dry ice packs + Cold packs Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 10 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Descripción general

IR-783 (ADS 780WS) is a near-infrared (NIR) heptamethine cyanine fluorescent probe. IR-783 significantly inhibits tumour growth and induces apoptosis in MDA-MB-231 xenograft model. IR-783 can be used to study breast cancer.

Specifications

Especificaciones y pureza
Moligand™, 10 mM in DMSO
Condiciones de almacenamiento de almacenamiento
Desiccated, Store at -80°C
Enviado en
Dry ice packs + Cold packs
Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.
Grado
Moligand™
Nombres e identificadores
Isómeros SMILES CC1(C2=CC=CC=C2[N+](=C1C=CC3=C(C(=CC=C4C(C5=CC=CC=C5N4CCCCS(=O)(=O)[O-])(C)C)CCC3)Cl)CCCCS(=O)(=O)[O-])C.[Na+]
Peso molecular 749.35
Reaxy-Rn 14503446
Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=14503446&ln=

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Certificados (CoA, COO, BSE/TSE y tabla de análisis)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:
Propiedades químicas y físicas
Punto de fusión (°C)212 °C
Preguntas frecuentes y artículos
Citations of This Product
Referencias
1. Xiaoxia Wu, Dinghu Zhang, Ting Pan, Jianwei Li, Yujiao Xie, Chenguang Zhang, Chunshu Pan, Zhewei Zhang, Jie Lin, Aiguo Wu, Guoliang Shao.  (2023)  Stimuli-Responsive Codelivery System Self-Assembled from in Situ Dynamic Covalent Reaction of Macrocyclic Disulfides for Cancer Magnetic Resonance Imaging and Chemotherapy.  ACS Applied Materials & Interfaces,      [PMID:37721368] [10.1021/acsami.3c10245]
2. Mingzhi Zhu, Pei Wang, Biaoqi Chen, Linrong Shi, Ruimin Long, Shibin Wang, Yuangang Liu.  (2023)  Active-oxygenating hollow Prussian blue nanosystems loaded with biomacromolecules for photodynamic/photothermal therapy of cancer and alleviating hypoxic tumors.  MATERIALS & DESIGN,      [PMID:] [10.1016/j.matdes.2023.112618]
3. Wei Zhang, Yibao Fan, Jinze Zhang, Dan Shi, Jiahui Yuan, Milad Ashrafizadeh, Wei Li, Man Hu, A.M. Abd El-Aty, Ahmet Hacimuftuoglu, Michael Linnebacher, Yongxian Cheng, Weiguang Li, Shuo Fang, Peng Gong, Xianbin Zhang.  (2023)  Cell membrane-camouflaged bufalin targets NOD2 and overcomes multidrug resistance in pancreatic cancer.  DRUG RESISTANCE UPDATES,      [PMID:37647746] [10.1016/j.drup.2023.101005]
4. Jiaqi Zhou, Hao Li, Hui Li, Jiayi Ding, Zhong Du, Jiabao Xiong, Hongyang Yao, Xueliang Zhang, Nuernisha Alifu, Biao Dong.  (2025)  Constructing J-aggregates of Cyanine Dye for NIR-II in vivo Dynamic Vascular Imaging and Long-Term Targeting of Tumors.  Materials Today Bio,      [PMID:40242486] [10.1016/j.mtbio.2025.101693]
5. Man Zhang, Ke Li, Junhao Kou, Guozhi Lu, Ling Qiu, Chunzhao Yang, Yongchun Liu, Qi Xue, Peng Yang.  (2024)  Functionalized Amyloid-Like Protein Nanofilm-Mediated Synergistic Disulfidptosis and Photodynamic Therapy for Preventing Postoperative Recurrence of Colorectal Cancer.  Small Science,      [PMID:] [10.1002/smsc.202400323]
6. Wenrun Li, Li Shen, Shiyan Fu, Yong Li, Feng Huang, Qi Li, Qinyang Lin, Hongjia Liu, Qiuchi Wang, Liyi Chen, Huanhuan Tan, Juan Li, Yazhen Zhao, Yonghong Ran, Yuhui Hao.  (2024)  Mitochondrial-Targeting Mesoporous Polydopamine Nanoparticles for Reducing Kidney Injury Caused by Depleted Uranium.  Advanced Healthcare Materials,      [PMID:39543790] [10.1002/adhm.202403015]
7. Fan Yibao, Zhang Wei, Iqbal Zoya, Li Xinxin, Lin Zhiyin, Wu Zhuolin, Li Qianyou, Dong Hongxia, Zhang Xianbin, Gong Peng, Liu Peng.  (2024)  Rod-shaped mesoporous silica nanoparticles reduce bufalin cardiotoxicity and inhibit colon cancer by blocking lipophagy.  Lipids in Health and Disease,  23  (1): (1-12).  [PMID:39334257] [10.1186/s12944-024-02301-y]
8. Wu Xiao-Xia, Zhang Ding-Hu, Ding Yi-Nan, Cao Fei, Li Yang, Yao Jun-Lie, Miao Xin-Yu, He Lu-Lu, Luo Jun, Li Jian-Wei, Lin Jie, Wu Ai-Guo, Zheng Jia-Ping.  (2024)  Self-assembled co-delivery system of gold nanoparticles and paclitaxel based on in-situ dynamic covalent chemistry for synergistic chemo-photothermal therapy.  RARE METALS,  44  (1): (417-429).  [PMID:] [10.1007/s12598-024-03047-3]
9. Man Zhang, Junhao Kou, Zhenyi Song, Ling Qiu, Chunzhao Yang, Qi Xue.  (2025)  A Janus Amyloid-like Nanofilm Inhibits Colorectal Cancer Postoperative Recurrence and Abdominal Adhesion via Synergistic Enzyme Cascade.  Nanomaterials,  15  (9): (670).  [PMID:40358287] [10.3390/nano15090670]
10. Weijie Wang, Chenguang Sun, Linhao Jing, Yaning Xia, Shuijun Zhang, Yupeng Shi.  (2025)  Light-driven secondary structural remodeling in biomimetic nanosystem to enhance tumor chemo-phototherapy.  Materials Today Bio,      [PMID:40538753] [10.1016/j.mtbio.2025.101955]
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