Isosakuranetin - Moligand™, ≥98% , Channel blocker of TRPM3, CAS No.480-43-3, Channel blocker of TRPM3

CAS: 480-43-3 Cat. No.: I414404 Peso molecular: 286.28 Número EC: 207-551-8
Disponible para pedir
GRADE & PURITY Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
Synonyms
BRD-K19341706-001-01-7 | CCG-208396 | 5'-METHYL-2'-HYDROXYACETOPHENONE | SR-05000002273-2 | EINECS 207-551-8 | 5,7-dihydroxy-4''-methoxyflavanone | 5,7-Dihydroxy-4'-methoxyflavanone | (S)-2,3-dihydro-5,7-dihydroxy-2-(4-methoxyphenyl)-4H-1-benzopyran-4-one
Storage
Protected from light,Store at -20°C
Shipped In
Ice chest + Ice pads
 ·  off list, applied to all prices below.
Size
Estado
Price
Qty
5mg
I414404-5mg
2
226,90US$
10mg
I414404-10mg
2
387,90US$
25mg
I414404-25mg
2
676,90US$
50mg
I414404-50mg
2
1.128,90US$
100mg
I414404-100mg
2
1.524,90US$
Enter a quantity for the sizes you want to add.
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Why this grade

Moligand™, ≥98% Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Protected from light,Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Descripción general

Information

Isosakuranetin (4'-Methylnaringenin), an O-methylated flavonoid, is the 4'-methoxy derivative of naringenin, a flavanone found inCitrusspecies.

Specifications

Sinónimos
BRD-K19341706-001-01-7 | CCG-208396 | 5'-METHYL-2'-HYDROXYACETOPHENONE | SR-05000002273-2 | EINECS 207-551-8 | 5, 7-dihydroxy-4''-methoxyflavanone | 5, 7-Dihydroxy-4'-methoxyflavanone | (S)-2, 3-dihydro-5, 7-dihydroxy-2-(4-methoxyphenyl)-4H-1-benzopyran-4-one
Especificaciones y pureza
Moligand™, ≥98%
Mecanismos bioquímicos y fisiológicos
Isosakuranetin (4'-Methylnaringenin), an O-methylated flavonoid, is the 4'-methoxy derivative of naringenin, a flavanone found in Citrus species.
Condiciones de almacenamiento de almacenamiento
Protected from light, Store at -20°C
Enviado en
Ice chest + Ice pads
Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.
Grado
Moligand™
Tipo de acción
CHANNEL BLOCKER
Mecanismo de acción
Channel blocker of TRPM3
Pureza
≥98%
Propiedades del producto
ALogP2.599
hba_count3
Recuento HBD2
Enlace rotable2
Nombres e identificadores
Pubchem Sid488188316
Pubchem Sid Urlhttps://pubchem.ncbi.nlm.nih.gov/substance/488188316
Sonrisas canónicasCOC1=CC=C(C=C1)C2CC(=O)C3=C(C=C(C=C3O2)O)O
IUPAC Name(2S)-5,7-dihydroxy-2-(4-methoxyphenyl)-2,3-dihydrochromen-4-one
InChIKeyHMUJXQRRKBLVOO-AWEZNQCLSA-N
INCHI1S/C16H14O5/c1-20-11-4-2-9(3-5-11)14-8-13(19)16-12(18)6-10(17)7-15(16)21-14/h2-7,14,17-18H,8H2,1H3/t14-/m0/s1
Isómeros SMILES COC1=CC=C(C=C1)[C@@H]2CC(=O)C3=C(C=C(C=C3O2)O)O
CAS alternativo 480-43-3
Términos de entrada MeSH isosakuranetin
Peso molecular 286.28
Reaxy-Rn 91628
Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=91628&ln=

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Taxonomic Classification

Taxonomy Tree

KingdomOrganic compounds
SuperclassPhenylpropanoids and polyketides
ClaseFlavonoids
SubclassO-methylated flavonoids
Intermediate Tree Nodes Not available
Direct Parent4'-O-methylated flavonoids
Alternative Parents Flavanones  7-hydroxyflavonoids  5-hydroxyflavonoids  Chromones  Phenoxy compounds  Methoxybenzenes  Aryl alkyl ketones  Anisoles  Alkyl aryl ethers  1-hydroxy-4-unsubstituted benzenoids  1-hydroxy-2-unsubstituted benzenoids  Vinylogous acids  Oxacyclic compounds  Organic oxides  Hydrocarbon derivatives  
Molecular FrameworkAromatic heteropolycyclic compounds
Substituents 4p-methoxyflavonoid-skeleton - 5-hydroxyflavonoid - 7-hydroxyflavonoid - Flavanone - Hydroxyflavonoid - Flavan - Chromone - Benzopyran - Chromane - 1-benzopyran - Phenoxy compound - Methoxybenzene - Anisole - Phenol ether - Aryl ketone - Aryl alkyl ketone - Alkyl aryl ether - 1-hydroxy-4-unsubstituted benzenoid - 1-hydroxy-2-unsubstituted benzenoid - Monocyclic benzene moiety - Benzenoid - Vinylogous acid - Ketone - Oxacycle - Organoheterocyclic compound - Ether - Organic oxide - Organic oxygen compound - Organooxygen compound - Hydrocarbon derivative - Aromatic heteropolycyclic compound
DescripciónThis compound belongs to the class of organic compounds known as 4'-o-methylated flavonoids. These are flavonoids with methoxy groups attached to the C4' atom of the flavonoid backbone.
External Descriptors Flavanones
Estructura 3D
Modelo de Estructura Química Interactiva





Objetivos asociados (humanos)
TRPM3 Tchem Transient receptor potential cation channel subfamily M member 3 (1 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
ACHE Tclin Acetylcholinesterase (18204 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
XDH Tclin Xanthine dehydrogenase (1038 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CYP1B1 Tchem Cytochrome P450 1B1 (1148 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CYP1A1 Tchem Cytochrome P450 1A1 (1169 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CYP1A2 Tchem Cytochrome P450 1A2 (26471 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HCT-116 (91556 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Monocyte (474 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Objetivos asociados (no humanos)
L929 (3802 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
rep Replicase polyprotein 1ab (378 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
BCHE Cholinesterase (8742 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Cladosporium cladosporioides (101 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Cladosporium sphaerospermum (47 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Rorc Nuclear receptor ROR-gamma (89407 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
FTL Ferritin light chain (43324 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mecanismos de acción
Certificados (CoA, COO, BSE/TSE y tabla de análisis)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

11 results found

Lot NumberCertificate TypeFechaArticulo
B2327728Certificate of AnalysisDec 22, 2025 I414404
B2327708Certificate of AnalysisDec 22, 2025 I414404
B2327705Certificate of AnalysisDec 22, 2025 I414404
B2327700Certificate of AnalysisDec 22, 2025 I414404
B2327699Certificate of AnalysisDec 22, 2025 I414404
B2327698Certificate of AnalysisDec 22, 2025 I414404
B2327696Certificate of AnalysisDec 22, 2025 I414404
B2327695Certificate of AnalysisDec 22, 2025 I414404
B2327701Certificate of AnalysisAug 08, 2022 I414404
B2327704Certificate of AnalysisAug 08, 2022 I414404
C2506055Certificate of AnalysisAug 08, 2022 I414404

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Propiedades químicas y físicas
SolubilidadSolubility (25°C) In vitro DMSO: 57 mg/mL (199.1 mM);    
Sensibilidadlight & moisture & heat sensitive
DMSO (mg/ml) Solubilidad máxima57
DMSO (mM) Solubilidad máxima199.106215690855
Peso molecular286.280 g/mol
XLogP32.700
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count5
Rotatable Bond Count2
Exact Mass286.084 Da
Monoisotopic Mass286.084 Da
Topological Polar Surface Area76.000 Ų
Heavy Atom Count21
Formal Charge0
Complexity377.000
Isotope Atom Count0
Defined Atom Stereocenter Count1
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
The total count of all stereochemical bonds0
Covalently-Bonded Unit Count1
Calculadoras de soluciones
Reseñas

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