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· · COA & SDS Disponible para cada producto · Same-day shipping on in-stock items IU1 - Moligand™, 10mM in DMSO , Inhibitor of ubiquitin specific peptidase 14, CAS No.314245-33-5, Inhibitor of ubiquitin specific peptidase 14
GRADE & PURITY Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10mM in DMSO Synonyms
BDBM50437694 | HMS2742M13 | Usp14 inhibitor | AMY24153 | NCGC00249377-08 | HMS3743A07 | EN300-72884 | MFCD01917473 | SR-01000010584 | 1-(1-(4-fluorophenyl)-2,5-dimethyl-1H-pyrrol-3-yl)-2-(pyrrolidin-1-yl)ethanone | SCHEMBL6923146 | EX-A2079 | MLS001032847
Shipped In
Dry ice packs + Cold packs
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Why this grade Moligand™, 10mM in DMSO Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
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Storage & shipping Store at -80°C Ships Dry ice packs + Cold packs Check lot-specific COA for exact specifications.
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Quality documents SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
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Literature proof Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Descripción general IU1 is a special Usp14 inhibitor with an IC50 of 4-5 μM.
Specifications Sinónimos
BDBM50437694 | HMS2742M13 | Usp14 inhibitor | AMY24153 | NCGC00249377-08 | HMS3743A07 | EN300-72884 | MFCD01917473 | SR-01000010584 | 1-(1-(4-fluorophenyl)-2, 5-dimethyl-1H-pyrrol-3-yl)-2-(pyrrolidin-1-yl)ethanone | SCHEMBL6923146 | EX-A2079 | MLS001032847
Especificaciones y pureza
Moligand™, 10mM in DMSO
Mecanismos bioquímicos y fisiológicos
Selective, reversible Usp14 inhibitor (IC 50 = 4 μM). Enhances degradation of proteasome substrates. Reduces rate of ubiquitin chain trimming bound to cyclin B or other ubiquitin chains. Active in vitro . Cell-permeable.
Condiciones de almacenamiento de almacenamiento
Store at -80°C
Enviado en
Dry ice packs + Cold packs
Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.
Mecanismo de acción
Inhibitor of ubiquitin specific peptidase 14
Nombres e identificadores Sonrisas canónicas CC1=CC(=C(N1C2=CC=C(C=C2)F)C)C(=O)CN3CCCC3 IUPAC Name 1-[1-(4-fluorophenyl)-2,5-dimethylpyrrol-3-yl]-2-pyrrolidin-1-ylethanone InChIKey JUWDSDKJBMFLHE-UHFFFAOYSA-N INCHI 1S/C18H21FN2O/c1-13-11-17(18(22)12-20-9-3-4-10-20)14(2)21(13)16-7-5-15(19)6-8-16/h5-8,11H,3-4,9-10,12H2,1-2H3 Isómeros SMILES CC1=CC(=C(N1C2=CC=C(C=C2)F)C)C(=O)CN3CCCC3 WGK Alemania 3 Peso molecular 300.37 Reaxy-Rn 21391902 Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=21391902&ln=
Documentation 📋 Safety Data Sheet (SDS) Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS → ✅ Certificate of Analysis (COA) Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA → 📊 Datasheet Quick-reference summary of product specifications and applications.
View datasheet → 🔬 Specification Sheet Full quality attributes and acceptance criteria for this grade.
View spec sheet →
Advanced Data Taxonomic Classification Kingdom Organic compounds Superclass Organoheterocyclic compounds Clase Pyrroles Subclass Substituted pyrroles Intermediate Tree Nodes Not available Direct Parent Phenylpyrroles Alternative Parents Aryl alkyl ketones Fluorobenzenes N-alkylpyrrolidines Aryl fluorides Vinylogous amides Heteroaromatic compounds Alpha-amino ketones Trialkylamines Azacyclic compounds Organopnictogen compounds Organofluorides Organic oxides Hydrocarbon derivatives Molecular Framework Aromatic heteromonocyclic compounds Substituents 1-phenylpyrrole - Aryl alkyl ketone - Aryl ketone - Fluorobenzene - Halobenzene - Aryl fluoride - Aryl halide - Monocyclic benzene moiety - N-alkylpyrrolidine - Benzenoid - Alpha-aminoketone - Heteroaromatic compound - Pyrrolidine - Vinylogous amide - Ketone - Tertiary amine - Tertiary aliphatic amine - Azacycle - Amine - Organooxygen compound - Organonitrogen compound - Organofluoride - Organohalogen compound - Hydrocarbon derivative - Organic oxide - Organopnictogen compound - Organic oxygen compound - Organic nitrogen compound - Aromatic heteromonocyclic compound Descripción This compound belongs to the class of organic compounds known as phenylpyrroles. These are polycyclic aromatic compounds containing a benzene ring linked to a pyrrole ring through a CC or CN bond. External Descriptors Not available Data sources 1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.
Estructura 3D Objetivos asociados (humanos) Objetivos asociados (no humanos) Mecanismos de acción Certificados (CoA, COO, BSE/TSE y tabla de análisis) Propiedades químicas y físicas Peso molecular 300.400 g/mol XLogP3 3.500 Hydrogen Bond Donor Count 0 Hydrogen Bond Acceptor Count 3 Rotatable Bond Count 4 Exact Mass 300.164 Da Monoisotopic Mass 300.164 Da Topological Polar Surface Area 25.200 Ų Heavy Atom Count 22 Formal Charge 0 Complexity 389.000 Isotope Atom Count 0 Defined Atom Stereocenter Count 0 Undefined Atom Stereocenter Count 0 Defined Bond Stereocenter Count 0 Undefined Bond Stereocenter Count 0 The total count of all stereochemical bonds 0 Covalently-Bonded Unit Count 1
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