(±)-J 113397 - ≥98% , CAS No.217461-40-0

CAS: 217461-40-0 Cat. No.: J287289 Fórmula: C₂₄H₃₇N₃O₂ Peso molecular: 399.57 PubChem CID: 90488772

GRADE & PURITY ≥98%

Synonyms

(±)-1-[(3R*,4R*)-1-(Cyclooctylmethyl)-3-(hydroxymethyl)-4-piperidinyl]-3-ethyl-1,3-dihydro-2H-benzimidazol-2-one

Storage

Protected from light,Store at -20°C,Desiccated

Shipped In

Ice chest + Ice pads

Specifications

Sinónimos

(±)-1-[(3R*,4R*)-1-(Cyclooctylmethyl)-3-(hydroxymethyl)-4-piperidinyl]-3-ethyl-1,3-dihydro-2H-benzimidazol-2-one

Especificaciones y pureza

≥98%

Mecanismos bioquímicos y fisiológicos

(±) - J-113397 is an effective and selective non peptide ORL1 receptor antagonist with a Ki of 1.8 nM against human cloned ORL1. J-113397 inhibits the binding of GTP γ S stimulated by nociceptin/orphan FQ to CHO cells expressing ORL1, with an IC50 value o

Condiciones de almacenamiento de almacenamiento

Protected from light,Store at -20°C,Desiccated

Enviado en

Ice chest + Ice pads

Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.

Tipo de acción

ANTAGONIST

Pureza

≥98%

Nombres e identificadores

Sonrisas canónicas

CCN1C4=C(C=CC=C4)N([C@@H]2CCN(CC3CCCCCCC3)C[C@H]2CO)C1=O.CCN5C8=C(C=CC=C8)N([C@H]6CCN(CC7CCCCCCC7)C[C@@H]6CO)C5=O

InChIKey

NLSVMRCGZVSAFK-SDNSQTLOSA-N

Isómeros SMILES

CCN1C2=CC=CC=C2N(C1=O)[C@@H]3CCN(C[C@H]3CO)CC4CCCCCCC4.CCN1C2=CC=CC=C2N(C1=O)[C@H]3CCN(C[C@@H]3CO)CC4CCCCCCC4

PubChem CID

90488772

Peso molecular

399.57

Propiedades químicas y físicas

• Solubilidad: Solvent:DMSO, Max Conc. mg/mL: 19.98, Max Conc. mM: 50; Solvent:ethanol, Max Conc. mg/mL: 19.98, Max Conc. mM: 50
• Sensibilidad: Light and Moisture sensitive

Preguntas frecuentes

What is the purity of this product?

This product is supplied at ≥98% purity (chemical assay). Lot-specific values are stated on the Certificate of Analysis.

How should this product be stored?

Store at ?20 °C, protected from light, desiccated. Keep the container tightly closed with desiccant — the material is moisture-sensitive.

How is this product shipped?

This product ships in an insulated container with ice pads. Unpack on arrival and transfer it to the storage condition stated above.

What are the CAS number, molecular formula and molecular weight?

The CAS Number is 217461-40-0, the molecular formula is C24H37N3O2, and the molecular weight is 399.57 g/mol. InChIKey NLSVMRCGZVSAFK-SDNSQTLOSA-N.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.