J-113863 - Moligand™, 10 mM in DMSO , CAS No.353791-85-2

CAS: 353791-85-2 Cat. No.: J1493658 Peso molecular: 655.44 PubChem CID: 6918496

GRADE & PURITY Moligand™, 10 mM in DMSO

Storage

Desiccated,Store at -80°C

Shipped In

Dry ice packs + Cold packs

Descripción general

J-113863 is a potent and selective CCR1 antagonist with IC 50 values of 0.9 nM and 5.8 nM for human and mouse CCR1 receptors, respectively. J-113863 is also a potent antagonist of the human CCR3 ( IC 50 of 0.58 nM) , but a weak antagonist of the mouse CCR3 ( IC 50 of 460 nM). J-113863 is inactive against CCR2 , CCR4 and CCR5 , as well as the LTB4 or TNF-α receptors. Anti-inflammatory effect.

Specifications

Especificaciones y pureza

Moligand™, 10 mM in DMSO

Condiciones de almacenamiento de almacenamiento

Desiccated, Store at -80°C

Enviado en

Dry ice packs + Cold packs

Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.

Grado

Moligand™

Tipo de acción

ANTAGONIST

Nombres e identificadores

• Isómeros SMILES: CC[N+]1(CCC(CC1)NC(=O)C2C3=C(C=CC(=C3)Cl)OC4=C2C=C(C=C4)Cl)C/C/5=C/CCCCCC5.[I-]
• RTECS: TN4770000
• PubChem CID: 6918496
• Peso molecular: 655.44