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JHDM-IN-1 , CAS No.1310809-17-6
Disponible para pedir
Storage
Store at -20°C
Shipped In
Ice chest + Ice pads
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Why this grade
for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Storage & shipping
Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.
Quality documents
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Literature proof
Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Descripción general
JHDM-IN-1 (Compound 1) is a Jumonji C domain-containing HDMs ( JHDM ) inhibitor with IC 50 s of 3.4, 4.3, 5.9, 10 and 43 μM against JMJD2C, JMJD2A, JMJD2E, PHF8 and JMJD3, respectively
In Vitro
JHDM-IN-1 (Compound 1) also inhibits FIH, PHD3, PHD1, PHD2 and LSD1 with IC 50 s of 22, 31, 54, 83 and 620 μM, respectively. JHDM-IN-1 (0-100 μM) does not inhibit KYSE150 cell growth after treatment for 48 h. MCE has not independently confirmed the accuracy of these methods. They are for reference only.
Form:Solid
IC50& Target:IC50: 3.4 μM (JMJD2C), 4.3 μM (JMJD2A), 5.9 μM (JMJD2E), 10 μM (PHF8), 22 μM (FIH), 31 μM (PHD3), 43 μM (JMJD3), 54 μM (PHD1), 83 μM (PHD2), 620 μM (LSD1)
Specifications
Mecanismos bioquímicos y fisiológicos
JHDM-IN-1 (Compound 1) is a Jumonji C domain-containing HDMs ( JHDM ) inhibitor with IC 50 s of 3.4, 4.3, 5.9, 10 and 43 μM against JMJD2C, JMJD2A, JMJD2E, PHF8 and JMJD3, respectively.
Condiciones de almacenamiento de almacenamiento
Store at -20°C
Enviado en
Ice chest + Ice pads
Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.
Tipo de acción
INHIBITOR
Nombres e identificadores
| Peso molecular | 491.54 |
|---|
Documentation
📋 Safety Data Sheet (SDS)
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →✅ Certificate of Analysis (COA)
Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →🔬 Specification Sheet
Full quality attributes and acceptance criteria for this grade.
View spec sheet →Advanced Data
Certificados (CoA, COO, BSE/TSE y tabla de análisis)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:
Calculadoras de soluciones
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